Wednesday, February 12, 2020

Super-precise CRISPR tool enhanced by enzyme engineering

Good news! CRISPR is becoming crisper!

"A super-precise version of the CRISPR genome-editing tool just got even better. Researchers have boosted the accuracy of a technique based on the popular but error-prone CRISPR–Cas9 system by engineering enzymes that can precisely target DNA without introducing as many unwanted mutations."


CRISPR-Cas9 gene editing complex, molecular structure.


Super-precise CRISPR tool enhanced by enzyme engineering: Improvements to a method known as base editing could pave the way for safer gene therapies.

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