Monday, March 30, 2020

Conservatives Are the Real Environmentalists

Recommendable!

When Rodents Rafted Across the Ocean

Amazing stuff! Rodents migrated from Africa to South America about 40 million years ago across the ocean.



Krisenbewältigung: Sie wissen nicht, was sie tun

Sehr empfehlenswert! Sehr scharfsinnig, spitz, und sarkastisch trifft es aber genau!

COVID-19: Breath Test for Corona

Great news! A breath test would probably beat the usual fever infrared thermometer testing anytime!

"Prof. Hossam Haick and his team have shifted their focus to applying nanosensor technology to facilitate rapid and remote screening for COVID-19. These intelligent sensory systems can be used to diagnose Corona, and future epidemics. The group’s research focuses on breath testing using nano-sensors and AI and on a skin patch. The method is non-invasive, fast and inexpensive, and is already undergoing clinical trials in a hospital where COVID-19 is being treated.

Among many honors, Prof. Haick’s research received a prestigious Bill & Melinda Gates grant in 2015."

COVID-19: Diagnostic Avant Garde: Breath Test for Corona

The Destructive And Lethal Virus Of Mass Hysteria

Posted: 3/30/2020

The virus of mass hysteria is so much worse than the SARS-CoV-2 virus. The vicious spiral is relentless. Politicians race to do more harm instead of appealing to common sense!  Mass media and other means of communication are eagerly spreading the most ludicrous news possible and so on …

How mad were our politicians when they thought they could just shut down large parts of the economy to counter a relatively harmless, but contagious virus? When the cure is obviously worse than the disease!

The much needed voices of reason are hiding and/or are drowned out! Omnipresent medieval superstition is still manifest destiny in the 20th year of the 21st century! Human evolution is very slow despite all the education efforts! Common sense is in very scarce supply and hard to come by in these times!

Coronakrise: Der Exodus der indischen inländischen Arbeitsmigranten

Wenn Politiker meinen, man koennte doch einfach die Wirtschaft abschalten wegen eines relativ harmlosen Virus anstelle von gezielten, bottom up Massnahmen!

Coronakrise: Der Exodus der indischen Arbeitsmigranten

Liberales Institut - Vorsicht vor einem Missbrauch des Notstands

Empfehlenswert!

"Krisenzeiten sind Blütezeiten des Staatsinterventionismus."

Liberales Institut - Vorsicht vor einem Missbrauch des Notstands: Es bedarf grosser Wachsamkeit der Gesellschaft, damit die Notlage nicht von Sonderinteressen ausgenützt wird.

The New Meaning Of Made In China

Posted: 3/30/2020

How times have changed rapidly! Yesterday, the integration of the economy of China into the world economy was paramount. For decades, Westerners were hoping to reform the communist totalitarian regime in China by opening up the Chinese market and economy.

Unfortunately, the political reform efforts under Deng Xiaoping were latest undone when Xi Jinping chose to be anointed to be the next dictator for life a la Mao in 2018. 

Made in China and the Road and Belt initiative have been very smart moves by the Communist Party of China to gain global influence if not domination at very high speed and very large scale.

Now, the coronavirus has driven home the message that the Communist Party of China has not changed at all. It resorted to the usual active and massive spread of disinformation, pervasive censorship and oppression of dissidents, almost total secrecy, refusal of international aid etc.   

Global supply chains depending on China need and most likely will be scrutinized and adjusted.

Let’s hope the coronavirus is the final nail in the coffin of the Communist Party of China!

Cases in U.S. By CDC: No Downloadable Data

CDC does not provide downloadable spreadsheets or CSV files of e.g. coronavirus infections by state! It is moronic of the CDC in the 20th year of the 21st century not to do so!!!!

It is not even possible to easily copy and paste the data from the tables of the webpage!

Cases in U.S. | CDC: See the number of people under investigation (PUIs) in the United States and states with confirmed cases of Coronavirus Disease 2019 (COVID-19).

The Painting Life of Vincent van Gogh

Very recommendable! Beautifully done! I did not know that his very close brother Theo would only die a few months after Vincent! Documentary displays a lot of early works in about the first half of the documentary!

Sunday, March 29, 2020

J. Haydn: Concerto para Trompete e orquestra em Mi bemol maior

Enjoy! The lady is a trumpet!

The complex geometry of Islamic design - Eric Broug

Recommendable!

Das Dürer-Selbstbildnis: Neue Erkenntnisse

Empfehlenswert!

BELARUS: Time to rebel AGAINST PUTIN?

Very recommendable! When two strong willed and minded dictators try to dance with each other!

The Indo-Israel Project: A Growing Agro Partnership

Israel helps to feed the largest population of vegetarians in the world!

This Ingenious System Brings Water to the Chinese Desert

Recommendable!



Ancient Wheat Genome Reveals Clues to the Agricultural Past

Amazing stuff!

" ... wheat, which carbon dating showed was from between 1130 and 1000 BC, was genetically much more similar to modern domesticated varieties than to modern wild ones, suggesting that the plant lineage the samples came from had already been domesticated ... "

Ancient Wheat Genome Reveals Clues to the Agricultural Past | The Scientist Magazine®: A museum sample of a 3,000-year-old Egyptian crop plant yields genomic information that helps researchers track the plant’s domestication and migration.


Eighty years (and more) of Sutton Hoo

Recommendable! From the curator at the British Museum!

" ... The Sutton Hoo ship burial is one of the greatest archaeological discoveries of all time. ... Previously it was thought that post-Roman Britain descended into the ‘Dark Ages’, when these islands supposedly experienced a decline in civilisation, sophistication and cosmopolitanism in all areas of life Sutton Hoo helped to explode that myth forever. ... We now know that the mound cemetery containing the ship burial was part of a wider landscape of human activity that reached back for millennia, beyond the Anglo-Saxon era. Research on the Staffordshire Hoard, another gobsmacking Anglo-Saxon discovery made in 2009, revealed that the goldsmiths responsible for Sutton Hoo’s treasures could manipulate the material to enhance its qualities, using methods that can barely be fathomed. ... "

Eighty years (and more) of Sutton Hoo – The British Museum Blog: When I was a first-year history undergraduate, I came to the British Museum on a field trip. The Anglo-Saxon period was brand new to me at the time – the only reason I knew of ‘Sutton Hoo’ and its fame was because a helmet that had been found there was on the front of my [...]






Saturday, March 28, 2020

The Glow Of Love (2015 Remastered 12” Long Version): Luther Vandross

No matter who you are ... there is no better way to be ... Hold me, caress me, we are the sweet bouquet ... Can you feel around you ... We are enraptured in the glow of love ... We will always be like this ... In the glow of love  ... We will always reminiscence ... We are one having fun walking in the glow of love ...

Change - Searching: Luther Vandross

For so long ... What is in front of my eyes ... 

Nice saxophone interlude, nice percussion, nice beat, nice arrangement ... 

The Journey of Luther Vandross

What an amazing singer! Very recommendable!
Luther on Sesame Street, influenced by Dionne Warwick, Apollo Theater ...

The Much Abused Matthew effect

Posted: 3/28/2020

Recently, I watched episode 2 of Niall Ferguson's Networld documentary. He tried to explain certain network effects with the Matthew effect!

Apparently, sociologists like Robert K. Merton transferred this biblical narrative to describe certain effects in society. Merton is famous for such concepts as self fulfilling prophecy, unintended consequences, and role model. However, with the Matthew effect, he misappropriated and erred!

"The Matthew effect of accumulated advantage, Matthew principle, or Matthew effect for short, is sometimes summarized by the adage "the rich get richer and the poor get poorer""

Some observations regarding the so called Matthew effect:
  1. The references in the Bible refer to spiritual gains not material gains. It is also quite obvious that the usual Bible references are taken out of context (see e.g. S1)
  2. The sociological view of this effect is extremely static and relies on primitive/naive extrapolation, while in reality society (in particular an open and free society) is much more dynamic etc.

Potent coronavirus drug candidate designed using 3D structure of key viral enzyme

Great news! This appears to be very promising research into the virus major protease! This research covers SARS-CoV-2, MERS, and HIV! 


"The main Sars-CoV-2 protease is an enzyme that is crucial for the virus. It processes a large polyprotein – around 790kDa – that the virus makes by hijacking our own cell’s machinery, and then cleaves it into 12 smaller proteins that include the machinery the virus needs to replicate itself. The team at the University of Luebeck previously developed broad-spectrum inhibitors against this protease, known as α-ketoamides, for the major two types of coronaviruses that infect humans ... One compound, α-ketoamide 13b, inhibited the main protease of the virus, as well as the related Mers virus. The 13b inhibitor developed in Hilgenfeld’s lab was given to mice using a nebuliser without any adverse effects. This suggests direct delivery to the lungs may be feasible in Covid-19 patients. ... The virus’s major protease has been shown to be essential in other related viruses and as there are no identical proteases in the human body, it is a viable target,’ ... Perhaps the best example of protease inhibitors are those against HIV."


Potent coronavirus drug candidate designed using 3D structure of key viral enzyme | Research | Chemistry World: Inhibitor of Sars-CoV-2 protease shows promise in early animal tests


An image showing the chemical structures of α-ketoamide inhibitors

Learn about The Black Death with Dan Snow

Recommendable! Among many other things, we learn that some drastic changes in climate during the 1346-53 period caused e.g. poor harvests and hunger. A number of positive societal changes are also mentioned, e.g. massive change in land ownership distribution, better jobs and pay for peasants and workers, more participation of women in the economy etc. However, also the expansion of government power may have also increased in the aftermath by government assuming increased responsibility for public health

Ayn Rand - Monopoly and Anti-Trust

Highly recommendable! Ayn Rand nailed it! Intellectual property rights ought to be tremendously reduced or even eliminated!

Friday, March 27, 2020

Schockierende Zustände in deutschen Krankenhäusern: Bericht eines 40-jährigen Patienten

I am afraid this is not a singular or outlier case in a largely socialized health care system like Germany!



ALISON BALSOM - Sound the Trumpet (Royal Music of Purcell & Handel)

Recommendable, but a little too much talk! However, the sound quality is superb!

The Great Fall of China?

Recommendable! Betting on the downfall of the Communist Party of China! The Chinese people deserve better!

Despite Coronavirus, Sweden Refuses To Shutter Businesses and Limit Gatherings

Bravo Swedes! Way to go! One of the few voices of reason in our panic and hysteria ridden times!

Despite Coronavirus, Sweden Refuses To Shutter Businesses and Limit Gatherings – Reason.com: The Scandinavian country is betting against draconian restrictions and in favor of the free movement of people and goods.

COVID-19 needs a Manhattan Project

Not only COVID-19/SARS-CoV-2 needs a Manhattan Project or Human Genome Project or HIV/AIDS program, but also the common cold and influenza viruses!



COVID-19 needs a Manhattan Project | Science: There is an unprecedented race to develop a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With at least 44 vaccines in early-stage development, what outcome can we expect? Will the first vaccine to cross the finish line be the safest and most effective? Or will it be the most well-funded vaccines that first become available, or perhaps those using vaccine technologies with the fewest regulatory hurdles? The answer could be a vaccine that ticks all these boxes. If we want to maximize the chances for success, however, and have enough doses to end the coronavirus disease 2019 (COVID-19) pandemic, current piecemeal efforts won't be enough. If ever there was a case for a coordinated global vaccine development effort using a “big science” approach, it is now.

There is a strong track record for publicly funded, large-scale scientific endeavors that bring together global expertise and resources toward a common goal. The Manhattan Project brought about nuclear weapons quickly (although with terrible implications for humanity) through an approach that led to countless changes in how scientists from many countries work together. The Human Genome Project and CE

Thursday, March 26, 2020

Pachelbel Canon Performed At St Ann's Church, Manchester

What an earworm! Watch the feet in dress shoes tapping ... 

Aerial America: Arizona

Recommendable!

Aerial America: Arizona (Full Episode)

Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport

Good news! Amazing stuff! Antibiotic resistance is history! Did you know that some bacteria defend themselves against invasive bacteria by using poisons/bacteriocin

"Finally, we identify the minimal requirements for sensitizing Escherichia coli toward PyoS5, as well as other pyocins, and suggest that a generic pathway likely underpins the import of all TonB-dependent bacteriocins across the outer membrane of Gram-negative bacteria."

Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport | mBio: Pyocin S5 (PyoS5) is a potent protein bacteriocin that eradicates the human pathogen Pseudomonas aeruginosa in animal infection models, but its import mechanism is poorly understood. Here, using crystallography, biophysical and biochemical analyses, and live-cell imaging, we define the entry process of PyoS5 and reveal links to the transport mechanisms of other bacteriocins. In addition to its C-terminal pore-forming domain, elongated PyoS5 comprises two novel tandemly repeated kinked 3-helix bundle domains that structure-based alignments identify as key import domains in other pyocins. The central domain binds the lipid-bound common polysaccharide antigen, allowing the pyocin to accumulate on the cell surface. The N-terminal domain binds the ferric pyochelin transporter FptA while its associated disordered region binds the inner membrane protein TonB1, which together drive import of the bacteriocin across the outer membrane. Finally, we identify the minimal requirements for sensitizing Escherichia coli toward PyoS5, as well as other pyocins, and suggest that a generic pathway likely underpins the import of all TonB-dependent bacteriocins across the outer membrane of Gram-negative

Cracking down on corrosion with Hexigone Inhibitors

Good news! However, this invention dates seems to date back to 2015

Apparently, this new corrosion protection is already being marketed: 
Hexigone Inhibitors Ltd "In 2015, CEO and founder of Hexigone Inhibitors discovered a mechanism of protection that outperformed hexavalent chromate in laboratory tests, and the road to an innovate spin-out company began…  "

" ... The most common solution is to use corrosion inhibitors – additives and coatings that decrease the rate of corrosion. Until recently, hexavalent chromate was the most widely used. While effective, it’s extremely toxic, being both a carcinogen and a haemolytic capable of causing kidney and liver failure. ... "

Cracking down on corrosion with Hexigone Inhibitors | News | Chemistry World: Intelli-ion technology provides non-toxic, chromium-free protection from corrosion

Squid say hello with a light show

Amazing stuff!

"In the ocean’s dark reaches, these squid 'flashed' or 'flickered' when in the presence of others of their kind. To do so, the animals turned on internal bioluminescent organs that made their entire bodies glow — except where the glow was covered by overlying patterns of pigmentation.
But when squids pursued prey, they dimmed themselves. "

Squid say hello with a light show : Research Highlights: Marine creatures send signals to each other by combining bioluminescence and skin pigments.


Embedded droplet printing in yield-stress fluids

Good news! Amazing stuff!

"The discovery can transform a range of scientific applications including the study of biological and chemical processes, and can pave the way for more exquisite and targeted pharmaceutical and consumer products."

"Conventional microfluidic methods primarily rely on fluids that behave in simple ways, like water. Yield-stress fluids are materials that behave in a complex way, dramatically transitioning between solid-like and liquid-like behavior, depending on an applied stress. We introduce embedded droplet printing—a system for the generation and manipulation of fluid droplets within yield-stress fluids."


SMART announces new method for processing fluid droplets | MIT News: Researchers at the Singapore-MIT Alliance for Research and Technology and the National University of Singapore have developed a unique method for generating and processing fluid droplets under previously unattainable conditions. Microfluidics enables researchers to create unique environment for developing medicine, paving the way for more potent, high-quality drugs.


Embedded droplet printing in yield-stress fluids

Keynes: The Young Imperialist, 1906–13

Recommendable! More background on one of the most preeminent,  influential, and misleading economists of the 20th century!

Keynes: The Young Imperialist, 1906–13 | Mises Wire: John Maynard Keynes was the most influential economist of the twentieth century. Those interested in modern economics must ask: how did he become so influential? It is well known that his 1919 polemic The Economic Consequences of the Peace launched his career.

Millimetre-scale transceiver boosts ingestible sensors

Amazing stuff!

"While ingestible devices are in their infancy, their potential benefits are considerable. As well as helping to monitor digestive processes [over extended period of time] and diagnose gastrointestinal diseases, ingestibles could also replace procedures like endoscopic inspections and stool sample analyses ... several potential use cases, including ingestibles designed to monitor health, nutrition or biomarkers that indicate the presence of disease."

Millimetre-scale transceiver boosts ingestible sensors – Physics World: Wireless receiver and transmitter is small enough to fit in a swallowable capsule for monitoring gut health

Photo of the transceiver circuit next to a rolled-up version of the circuit inside a capsule

CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity

Good news! Well this expresses the true meaning of chimeric as in Chimeric Antigen Receptor (CAR) T cell. Cancer is history!

CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity | The Scientist Magazine®: A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.

By targeting flu-enabling protein, newly discovered antibody may protect against wide-ranging strains

Good news, but dated news (Oct. 2019)! Will we finally develop better flu vaccines! It is an enormous scandal that in the 20th year of the 21st century we are still not able to defeat viruses like influenza, common cold or coronavirus although we have the technology and knowledge to do so!

"A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or protect people against all strains of the virus. ... the antibody at the center of the study binds to a protein called neuraminidase, which is essential for the flu virus to replicate in the body"

By targeting flu-enabling protein, newly discovered antibody may protect against wide-ranging strains | Scripps Research The findings could lead to a universal flu vaccine and more effective emergency treatments.

Niall Ferguson’s Networld Documentary

Recommendable! However, Niall Ferguson has degenerated to a social justice warrior with paranoia!

What Ferguson completely overlooks is e.g. free email service, free Google office suite, free Google Translate service, free Google Map service, free Google Drive (up to 15GB) and much more. All these free apps and services make our daily lives so much better ...



Wednesday, March 25, 2020

Pandemie-Hysterie und das Ende der Freiheit

Sehr empfehlenswert! Eine Stimme der Vernunft!

How the Egg Came First

Very recommendable! So the human placenta is akin to a soft shell egg?

Jimi Hendrix: Life and Death of an Electric Alchemist

Recommendable!






MSF surprised that Iran put a stop to our coronavirus COVID-19 response

Are there similarities between totalitarian dictatorships irrespective of ideology?
Yes there are! Like China, Iran tries to eliminate or prevent outside help in times of crisis!

MSF surprised that Iran put a stop to our coronavirus COVID-19 response: In Iran, Ministry of Health officials have rescinded their approval of MSF’s COVID-19 intervention. We remain ready to help with the coronovirus response.


Iran Kicks Out Doctors Without Borders, Claims No Need for Aid: The Islamic regime of Iran notified Doctors Without Borders (MSF) it would withdraw approval of a shipment of medical aid to the country.

1968 Hong Kong Flu Pandemic Versus COVID-19

The 1968 Hong Kong flu pandemic killed an "killed an estimated one million people all over the world". As of 3/25/2020 the COVID-19 killed only a total of about 18,400 in over three months (Source).

Where are the voices of reason when you need them! Instead, governments all over the world are mired in panic and hysteria! 

1968 flu pandemic - Wikipedia

Green AI

Unfortunately, scientists are only all too human and succumb to the ideologies of the day! They too follow fads and fashions of the time! Or does a research paper with the catchy title "Green AI" garner more citations?

And if you think, I am picking here on some third rate scientists, you are mistaken. Take Noah A. Smith (one of the authors), his lifetime Google Scholar citation count is a very respectable 19938 (as of 3/25/2020) and he is with the Allen Institute for AI.

[1907.10597] Green AI: The computations required for deep learning research have been doubling every
few months, resulting in an estimated 300,000x increase from 2012 to 2018 [2].
These computations have a surprisingly large carbon footprint [38]. Ironically,
deep learning was inspired by the human brain, which is remarkably energy
efficient. Moreover, the financial cost of the computations can make it
difficult for academics, students, and researchers, in particular those from
emerging economies, to engage in deep learning research.
This position paper advocates a practical solution by making efficiency an
evaluation criterion for research alongside accuracy and related measures. In
addition, we propose reporting the financial cost or "price tag" of developing,
training, and running models to provide baselines for the investigation of
increasingly efficient methods. Our goal is to make AI both greener and more
inclusive
---enabling any inspired undergraduate with a laptop to write
high-quality research papers. Green AI is an emerging focus at the Allen
Institute for AI.

Nevada's Democrat Governor Outlaws Antimalarial Drugs for Coronavirus Sufferers

What a dimocratic fool and governor! Viva Las Vegas takes a hit!

Nolte: Nevada's Democrat Governor Outlaws Antimalarial Drugs for Coronavirus Sufferers: Nevada's Gov. Steve Sisolak signed an order Tuesday outlawing the use of a antimalarial drugs for sufferers of the coronavirus.

Modular Homes, Houses made from containers

Want an affordable, modern home? Residential housing is being developed by the company!

Container Houses - Adaptive Shelters: Modular Houses Modular Homes, Houses made from containers Adaptive Shelters provides modular and container homes for your large-scale residential and commercial building projects. Whether you’re building an RV park, government housing, hotel and suite accommodations or educational dormitories, our prefabricated container homes offer excellent quality, design and durability. Steel container homes are weatherproof, fireproof and …

Musical Robot Learns to Sing, Has Album Dropping on Spotify

Are we on the cusp of a new revolution in music? Hope so, because contemporary Western music like pop music has become so boring. Current pop music is like rap, hip hop, rap, hip hop ...

Credit to Deeplearning.ai The Batch by Andrew Ng

Musical Robot Learns to Sing, Has Album Dropping on Spotify - IEEE Spectrum Georgia Tech’s marimba-playing robot can now compose and sing its own music

Der Wettlauf gegen Covid-19

Empfehlenswert, aber widerlich viel Reklame!

Der Wettlauf gegen Covid-19 Weltweit forschen Unternehmen und Institute an Mitteln gegen SARS-CoV-2. Dabei gibt es erste Fortschritte. Viele Pharma-Hersteller versuchen, eine Abkürzung zu nehmen.

Jetzt erst recht: Den Staat einschränken - nicht die Bürger

Empfehlenswert, aber widerlich viel Reklame! Weniger Staat, mehr freie Zivilgesellschaft und mehr freie Marktwirtschaft!

Jetzt erst recht: Den Staat einschränken - nicht die Bürger
„Das deutsche Volk krankt seit vielen Jahrzehnten in allen seinen Schichten an einer falschen Auffassung vom Staat, von der Macht, von der Stellung der Einzelperson. Es hat den Staat zum Götzen gemacht und auf den Altar erhoben. Die Einzelperson, ihre Würde und ihren Wert hat es diesem Götzen geopfert.“ (Konrad Adenauer: Grundsatzrede über das Programm der CDU – NWDR, 06. März 1946)
Man besinne sich wieder an Konrad Adenauer's obige Aussage! Leider ist diese Aussage im 20 Jahr des 21sten Jahrhunderts immer noch wahr!

Israeli firm Nanox aims to disrupt mammograms and other X-rays

Good news! Will this machine become part of our annual health checkup?

"the Nanox.Arc could provide a full-body digital X-ray scan down to the cellular level“Because it’s digital, it’s multispectral. You don’t need different machines to do different kinds of imaging,” ... That includes mammography, CT, fluoroscopy and angiography, for instance. ... 
Nanox.Arc’s companion software, Nanox.Cloud, will be a cloud-based repository for all the imaging data.
Nanox.Cloud will also handle radiologist matching, online and offline diagnostics review and annotation, connectivity to diagnostic assistive artificial intelligence systems, and even billing and reporting."

Israeli firm aims to disrupt mammograms and other X-rays - ISRAEL21c: Nanox, based in Israel and Japan, is poised to digitize, democratize and totally revolutionize 125-year-old X-ray technology.

Paper Sheds Light on Infant Universe and Origin of Matter

The Institute for Advanced Study and the researchers refers to it as axiogenesis! We will find out whether this latest subatomic particle QCD axion will live up to its extensive expectations! This miracle particle is supposed to explain a lot of stuff!

"... the QCD axion was originally proposed to explain the so-called strong CP problem—why the strong force, which binds protons and neutrons together, unexpectedly preserves a symmetry called the Charge Parity (CP) symmetry. ... Kinetic energy, resulting from the motion of the QCD axion, produced additional baryons or ordinary matter. This slight tipping of the scale in favor of matter [rather than antimatter] would have had a pronounced cascade effect, paving the way for the universe as it is known today. ..."

Paper Sheds Light on Infant Universe and Origin of Matter | Institute for Advanced Study: A new study, conducted to better understand the origin of the universe, has provided insight into some of the most enduring questions in fundamental physics: How can the Standard Model of particle physics be extended to explain the cosmological excess of matter over antimatter? What is dark matter? And what is the theoretical origin of an unexpected but observed symmetry in

Coronavirus: Schweden scheut das direkte Verbot

Finally, voices of reason coming out of Sweden! Bravo! Trust citizens to be responsible! No massive lock downs, quarantines, business shutdowns ... ! Lessons for the so disappointing British prime minister Boris Johnson!

Coronavirus: Schweden scheut das direkte Verbot Offene Schulen, offene Restaurants, offene Skilifte: Schweden geht mit der Corona-Krise deutlich laxer um als die meisten anderen Länder Europas. Man setzt auf die Selbstverantwortung der Bürger statt auf direkte Verbote. Ob das gut geht, muss sich erst noch zeigen.

Breaking out: Brazil’s First Capital Command and the emerging prison-based threat

What is going on in Brazil? A dominant national and transnational organized crime syndicate operating out of the prison system in Brazil?

Breaking out: Brazil’s First Capital Command and the emerging prison-based threat | American Enterprise Institute - AEI: Key Points Much of Brazil’s deadly urban violence is the direct result of territorial battles involving the country’s powerful transnational organized crime groups, many of which trace their origins to the country’s dangerous and overcrowded prisons. The Primeiro Comando da Capital (PCC), or First Capital Command, took shape in São Paulo during the early 1990s, …

A Litany of Useless Laws Have Been Exposed By the Coronavirus

Some positive effects of the latest panic & hysteria! One can only hope that these useless laws & government regulations will not be reinstated again after the coronavirus pandemic!

A Litany of Useless Laws Have Been Exposed By the Coronavirus - Foundation for Economic Education: From coast to coast, governments are waving regulations, many of which appear to serve as no more than impediments to free exchange. If these measures exist simply to generate additional government revenue, the public should ask themselves, once the crisis has abated: should they exist at all?

Tuesday, March 24, 2020

What the history of pandemics can tell us about COVID-19

Recommendable! E.g. has Xi Jinping (General Secretary of the Communist Party of China) lost his mandate of heaven? Hope so!



James Lindsay: Deep Dive Into “Critical Social Justice” & How It Took Over the Humanities

Very recommendable! Lindsay exposes so much intellectual junk! Human follies know no bounds!

Start-up Hyzon kündigt 140-Tonnen Brennstoffzellen-Lkw an

Good news! Yes, fuel cells might be a better solution than electric cars! Stop government subsidies for electric vehicles!

"Hyzon setzt auf Wasserstoff als Energielieferant. Die Brennstoffzellen kommen von Horizon Fuel Cell aus Singapur [nicht Deutschland]. Das Unternehmen ist seit 2003 in diesem Sektor tätig. ... Für 2020 plant das Unternehmen mit einem Bus für die Stadt – basierend auf einer bestehenden Bus-Plattform. Weiterhin ist ein Schwerlast-Lkw geplant. Die Stadtbusse sowie Lkw sollen Ende des Jahres mit einem Gesamtgewicht von 15 bis 40 Tonnen am Markt angeboten werden."

Start-up Hyzon kündigt 140-Tonnen Brennstoffzellen-Lkw an - ingenieur.de: Hyzon Motors Inc. setzt als Newcomer auf den Brennstoffzellenantrieb und plant Wasserstoff als Energielieferant zu etablieren. Was das Start-up noch vorhat.

Vladimir Putin’s Encirclement Of Europe

Recommendable! It is a particular dim outlook on the defensive capabilities and the strategic disunity of the European Union/NATO.

The article does not touch upon e.g. Russia's latest efforts in weapons development like hypersonic missiles.

"Russian propaganda, going back to czarist and Soviet times, often claims that Western powers are encircling Russia, forcing Moscow to be belligerent against its wishes. ... The claim of encirclement serves well to justify Putin’s neo-imperial policies. Russia’s wars in Georgia (in 2008) and in Ukraine (ongoing since 2014), its support for Bashar al-Assad in Syria, and the various forms of political warfare it carries out in Europe and the United States are considered responses to a consistent Western offensive. ... Along Europe’s eastern frontier, from the Baltic to the Black Sea, Russia has a sizeable military presence and has demonstrated its willingness to invade and control territories (e.g., South Ossetia in Georgia; Crimea and eastern Ukraine). It has entrenched itself in Syria in order to buttress Assad, returning to a position of influence in the Middle East that it has not held since the late 1970s. It has developed a partnership of sorts with Erdogan’s Turkey, convincing it to buy S-400 air-defense systems and thereby making that country an ever less reliable U.S. ally. It has built or upgraded seven military bases in the Arctic region, gaining control of one of the key shipping arteries between Europe and Asia, estimated to be 40 percent faster than shipping through the Suez Canal. In a surprising show of force in late 2019, Russia surged ten submarines into the North Atlantic, demonstrating a capability that had been dormant since the late Cold War. And in recent months it has increased its engagement in the messy war in Libya, becoming a key player in direct competition with Turkey in the political dynamics of this Mediterranean area. ... European security is increasingly at the mercy of Russia, and not just along the tense but geographically limited Central European frontier that historically separated the core of Europe from Moscow’s westward imperial aspirations. ... To deal with such a geopolitical encirclement, European states are adopting increasingly separate policies. ... “normalize relations.” ... keeping energy deals with Moscow alive while not wanting to follow the openly pro-Russian approach ... two European powers ... together with Moscow supports the opposing side in the Libyan war while [other European powers] are behind the U.N.-approved government. ... The Central European EU and NATO members are at best perplexed and at worst deeply worried by their Western allies’ friendly overtures toward Russia. And this is just one aspect, centered on Russia, of the various intra-European rifts. ... There are no European solutions to these growing divisions. The European Union is a complex but fragile and inefficient political construction that, in a geopolitical competition with a risk-taking imperial Russia seeking to expand its influence over the European continent, is incapable of achieving strategic coherence among its members. ... aimed at increasing intra-EU military cooperation and development. But these efforts often give the impression that the EU is seeking “strategic autonomy” from the United States rather than addressing the security threats around its frontiers. ... Moreover, no matter how many new coordinating efforts are launched by the EU or even NATO, the hard truth is that only a few European states are willing to take security seriously, devoting the necessary resources and mustering the national will to compete with Russia. The military capabilities of most European states remain atrophied.  ... A strong, coherent Europe, even if suffused with anti-American sentiment, would be preferable to the current situation of a weak Europe appeasing Russia and allowing Chinese economic penetration. The former could conceivably maintain repose on the Continent and prevent further Russian encirclement. A Europe that protects itself and radiates stability would be a welcome geopolitical development. But there are no signs that this will happen. Europe cannot find strategic unity from within. The EU-driven push toward “strategic autonomy” derives less from a shared threat assessment than from an aversion to the United States as the protector of the West, combined with a particular disdain toward the Trump administration."

Vladimir Putin’s Encirclement Of Europe | National Review

On The Past, Present And Future Of Wahhabism

Very recommendable!

" ... [In the mid-18th century] Wahhabis were not just declaring takfir (excommunication) on people but were also fighting them as part of a jihad. ... In all phases of his preaching, however, he was insistent that true believers must show hatred and enmity to non-Wahhabi Muslims. ... When Wahhabism began, its adherents dismissed the vast majority of nominal Muslims as polytheists. This is because they were seen to be worshiping at the grave sites of saints and prophets. It was a duty for Wahhabis to pronounce takfir on these so-called polytheists and to show them enmity and hatred. ... For more than 150 years, Wahhabism was perceived by most of the world’s Muslims as a radical heresy. Only in the early 20th century did the Wahhabis come to an accommodation with mainstream Sunni Islam. ... The first Saudi state, which reigned in the first 60 years of the 18th century, adhered to militant Wahhabi doctrine. The second Saudi state maintained this identity in the 19th century. The third Saudi state, which was established in 1902 by King Abdulaziz Al Saud [Ibn Saud], began as a militant Wahhabi state but gradually shed this character. Ibn Saud deployed Wahhabi warriors to conquer the Arabian Peninsula in the first decades of his rule, but he later fought a war against the most radical of these militants. The kind of Wahhabism that prevailed thereafter was more restrained and subdued.

The Saudi leadership’s support for this kind of Wahhabism continued until just a few years ago, when Mohammad bin Salman (MbS), the crown prince of Saudi Arabia, started more forcefully to put Wahhabi clerics in their place. MbS’s vision is to create a Saudi Arabia less wedded to the religious establishment. ... For anyone who subscribes to Wahhabism, Shiism is a horrible polytheist heresy that ought to be eradicated. Anti-Shiism is endemic in Wahhabism. For today’s jihadis, as for traditional Wahhabis, Shiism is a much greater threat to true Islam than Christianity, Judaism, or the values of the West in general."


Hoover Fellow Profile: Cole Bunzel On The Past, Present And Future Of Wahhabism | Hoover Institution: Cole Bunzel is a Hoover fellow at the Hoover Institution. A historian and Arabist, he studies the history and contemporary affairs of the Islamic Middle East, with a particular focus on violent Islamism and the Arabian Peninsula. He is currently writing a book about the origins and history of Wahhabism, a fundamentalist sect of Sunni Islam. In this interview, Bunzel discussed

Seismic imaging technology sees deep inside the brain

Amazing stuff! Could this be a breakthrough in brain imaging? Three-dimensional ultrasound tomography is highly mobile, easily repeatable, and can be used for continuous monitoring of the brain!

"In a new study, [researchers] turned to a computational technique known as full-waveform inversion (FWI), which is used by geophysicists to extract three-dimensional images of the Earth’s subsurface from data collected by seismometers on the passage of waves underground. A nonlinear data-fitting procedure, FWI works by using real-world seismic data to create a rough model of subsurface conditions from which wave equations can be solved to produce mock data. The model is then iteratively improved until this output provides the best fit for the real-world data.
Instead ... the researchers ... envisage using a helmet-like mesh of 1024 ultrasound transceivers. ... This is the first time FWI has been applied to the task of imaging inside a human skull"

Contrast this with the two leading current imaging technologies:
"Both of the leading conventional techniques for performing imaging on the brain come with inherent limitations. MR imaging is unsuitable for use on patients who have – or are suspected could have – metallic implants or harbour foreign bodies. It is also impractical for use on severely obese, claustrophobic or uncooperative patients. X-ray CT, meanwhile, involves exposure to harmful ionizing radiation, ruling out its use with young patients or for continuous monitoring. Both modalities also require large, expensive, high-powered machines that cannot practically be set up outside of hospital or laboratory settings."

Seismic imaging technology sees deep inside the brain – Physics World: A computational technique originally developed for seismic imaging can generate high-resolution ultrasound images of the brain

Hybrid infrared–optical microscope could improve cancer diagnostics

Amazing stuff! This could be another major breakthrough in microscopy! 
All-digital histopathology without staining!

" ... adding an IR laser and an interference objective to an optical camera, which harnesses the strengths of both modalities. The hybrid microscope has the same high resolution, large field-of-view and accessibility of an optical system, while its software can use the IR data to compute an image that looks similar to a conventional stained sample. ... The researchers are now working to optimize machine-learning programs that can measure multiple IR wavelengths, creating images that readily distinguish between multiple cell types, and integrate that data with the detailed optical images to precisely map cancer within a sample. ... "

Hybrid infrared–optical microscope could improve cancer diagnostics – Physics World: A simple addition to a conventional microscope allows for all-digital histopathology

LOCKERUNG DER EU HAUSHALTSREGELN: Einzig vernünftiger Weg

Was faselt der inkompetente Jürgen Matthes, Leiter des Kompetenzfelds Internationale Wirtschaftsordnung und Konjunktur des Institut der deutschen Wirtschaft, da? Plappert wie sein Boss IW-Direktor Michael Hüther auch geannt Ladenhüter!

Der sog. Stabilitäts- und Wachstumspakt der EU, die Grundvoraussetzung der Waehrungsunion, wird seit Jahrzehnten von Mitgliedslaendern verletzt und mit Fuessen getreten unter der Aufsicht und mit dem Wohlwollen von SED Kanzlerin Merkel!

Einzig vernünftiger Weg | Institut der deutschen Wirtschaft: Die Europäische Union lockert für die Corona-Krise ihre Haushaltsregeln und nutzt die so genannten Ausweichklauseln des Stabilitäts- und Wachstumspaktes. An dem gesamten Pakt hält sie dagegen fest – und geht so den einzig vernünftigen Weg.

Der Mossad in geheimer Gesundheitsmission

This news article claims that Israel's Mossad clandestinely acquired coronavirus test kits from foreign sources. I am not sure that this is a smart move. Hope, this will not compromise the operations of the otherwise excellent Mossad!

Der Mossad in geheimer Gesundheitsmission | NZZ: Diesmal brachen Israels Topagenten nicht in iranische Warenlager ein, sie töteten auch keine echten oder vermeintlichen Terroristen. Ihr Einsatz verlief ganz friedlich – und galt dem Coronavirus.

J.M. Keynes’s Dreams of a Eugenic Future

Recommendable! The article mentions a publication by Keynes, which I do not remember at all, i.e. "Economic Possibilities for our Grandchildren" and claims that it "ranks among the best-known contributions in the economic writings of John Maynard Keynes". The latter, I seriously doubt!

That JMK was a proponent of government birth and population control is not a new claim! Apparently, birth and population control was very popular among Western intellectuals until the Third Reich!

The article does not mention that J. M. Keynes was a known homosexual, which may have also contributed to his sometimes extreme views!

J.M. Keynes’s Dreams of a Eugenic Future – AIER: Keynes’s futuristic vision also entailed a scientifically planned world of human heredity, ordered around a state policy of eugenics.

Monday, March 23, 2020

Isambard Kingdom Brunel: The Genius of the Industrial Revolution

Recommendable!

Boris Johnson announced that the UK will go into lockdown from this evening onwards

Very unfortunate that the British Prime Minister Boris Johnson is loosing his cool over this panic and hysteria! Very disappointing Boris Johnson!
Where are the voices of reason hiding?


The historic British common sense expressed by such famous phrases as  "Keep calm and carry on" is becoming a distant shadow of its former self! Very regrettable! Signs of our times!

This panic and hysteria is inexcusable e.g. when during this influenza season alone many more thousands have been hospitalized and have died already!

Spectator Evening Blend

CMIP6: the next generation of climate models explained

Recommendable overview article! However, like weather forecast models cannot predict weather more than 48 hours in advance with any accuracy, climate models cannot predict climate over decades or let alone for 100 years! Weather models and climate models are very similar in their size, complexity, and science involved!

Our understanding of climate is still very incomplete! Thus, these modeling attempts are at best guesses and should be treated as such! We still know very little about the sun, cloud formation, ocean currents and biology and much more ...

Since too many climate scientist involved in the climate modeling are too biased, the output of these models reflect that!

Climate scientists try to dazzle us with pompous terms like equilibrium climate sensitivity! In reality, ECS is more baloney than anything else!
"... Researchers are currently looking into what is driving these high ECS values. In a number of models the increase in ECS appears to be due to their improved representation of clouds and aerosols; for example, how models treat supercooled clouds (below freezing but still liquid) in the Southern oceans can make a big difference in resulting sensitivity. ... However, despite making the models more realistic, it is not yet clear whether these improvements are translating into more accurate estimates of ECS."

CMIP6: the next generation of climate models explained | Carbon Brief: Climate models are one of the primary means for scientists to understand how the climate has changed in the past and may change in the future. These models simulate the physics, chemistry and biology of the atmosphere, land and oceans in great detail, and require some of the largest supercomputers in the world to generate their climate projections.

Princeton scientists discover surprising quantum effect in an exotic superconductor

Amazing stuff (dated Nov. 2019)! Are we coming any closer to a room temperature superconductor?

"The researchers probed the behavior of iron-based superconductors when impurities – namely atoms of cobalt – are added to explore how superconductivity forms and dissipates. Their findings led to new insights into a 60-year old theory of how superconductivity behaves. ... Cobalt appears to be one of these exceptions. Contrary to the theory, the addition of cobalt forces the iron-based superconductor to lose its superconducting ability and become like an ordinary metal ... discovered that each cobalt atom has a limited local impact that vanishes an atom or two in distance away from the impurity. However, there is a strong, systematic evolution through a phase transition into a normal, non-superconducting state as the cobalt concentration increases. ... "

Princeton scientists discover surprising quantum effect in an exotic superconductor – Discovery: Research at Princeton: Superconductors are already in use in various capacities, but newer iron-based superconductors are an active area of investigation. Researchers led by a Princeton team have studied what happens to …

New AI System Predicts Seizures With Near-Perfect Accuracy

Good news (but dated from Nov. 2019)!

"... the researchers incorporated another classification approach whereby a deep learning algorithm extracts and analyzes the spatial-temporal features of the patient’s brain activity from different electrode locations, boosting the accuracy of their model. And finally, EEG readings can involve multiple “channels” of electrical activity, ... applied an additional algorithm to identify the most appropriate predictive channels of electrical activity; this also speeds up the prediction process. ... With the software component complete, ... the next step is to develop a customized computer chip to process the algorithm"

New AI System Predicts Seizures With Near-Perfect Accuracy - IEEE Spectrum A novel AI design can accurately predict seizures up to one hour before they occur, with 99.6 accuracy

APOE Mutation Linked to Protection From Alzheimer's: Case Study

Good news (but dated from Nov. 2019)! Apparently, a woman in Colombia, who died in her 70s, had basically two opposing mutations. One of her mutations should have caused early onset of Alzheimers at around age 40, but she did not develop Alzheimer until her death due to a kind of offsetting, simultaneous mutation that protected her.

"The woman at the center of the study possesses a mutant version of PSEN1, a gene coding for a protein involved in processing amyloid precursor protein (APP) and other peptides. The variant is strongly associated with early-onset Alzheimer’s, with people showing signs of cognitive impairment by their mid-40s, and dementia by the time they’re 50. ... Using brain imaging, researchers found that the woman had extremely high levels of amyloid in her brain by the time she reached 70. However, she had little in the way of other signs of Alzheimer’s pathology, such as neurodegeneration or an accumulation of tau protein.  

“It actually illustrates ... for the first time, a very clear dissociation of amyloid accumulation from tau pathology, ... she possessed two copies of a rare mutation in APOE, another gene associated with Alzheimer’s risk. ... using in vitro experiments that the sequence, known in the scientific literature as the Christchurch variant, stops the protein product of the gene from binding strongly to its usual targets—sugar molecules involved in the accumulation of tau and neuron damage—and could thus have had a protective effect.  "



APOE Mutation Linked to Protection From Alzheimer's: Case Study | The Scientist Magazine®: A woman whose DNA suggested she'd develop early-onset dementia staved off cognitive decline for decades.

Coronavirus: Großbritannien verstaatlicht seine Bahnen

Was ist das denn fuer eine dumme Massnahme Boris Johnson? Sehr entaeuschend! Hoffe, das ist nur eine einmalige Entgleisung und nicht ein Omen!

Coronavirus: Großbritannien verstaatlicht seine Bahnen

Sunday, March 22, 2020

Die Ideen des Friedrich August von Hayek (Teil 1 & 2)

Sehr empfehlenswert! Gute darstellung der Ideen von Friedrich August von Hayek!

Z.B. Wettbewerb als Entdeckungsverfahren ist nicht exklusiv begrenzt auf das Wirtschaftsgeschehen sondern schliesst z.B. auch all gesellschaftliche Institutionen mit ein

Die Entstaatlichung des Geldes! Oder die Privatisierung des Geldes! 


"Why I left the left" Melanie Phillips on why she left the Guardian

Recommendable! Melanie Philips is a smart lady and she is e.g. the author of Londonistan!

Batterieforschung: Lithium für den Superakku

Good news!

"In diesem Zusammenhang ist ein Batterietyp wieder in den Fokus des Interesses gerückt, mit dem schon einer der Väter des Lithium-Ionen-Akkus, der Chemie-Nobelpreisträger von 2019 Stanley Whittingham, vor vierzig Jahren experimentierte, aber auch seine Probleme hatte: der Lithium-Metall-Akku. Weil die negative Elektrode (Anode) aus reinem Lithium besteht, ist er nicht nur leichter als ein klassischer Lithium-Ionen-Akku mit einer Graphit-Anode, er besitzt auch eine bis zu 65 Prozent höhere Energiedichte. ... Einen ungewöhnlichen Ansatz ... sind mikrometergroße würfelförmige Kapseln auf der positiven Elektrode, die während des Ladevorgangs geringe Mengen an Lithium-Fluorid an den Elektrolyten abgeben. Dadurch bildet sich von selbst ein für Lithium-Ionen durchlässiger Schutzfilm zwischen Elektrode und flüssigen Elektrolyten. Die winzigen Würfel trügen ... zudem dazu bei, dass sich das Lithium gleichmäßig auf der Anode ablagert und keine Kristalle entstünden. "

Batterieforschung: Lithium für den Superakku: Der Lithium-Metall-Akku erlebt eine Wiedergeburt. Denn er ist leichter, günstiger und deutlich leistungsfähiger als die klassische...

Saturday, March 21, 2020

Climate change: evidence and causes By The Royal Society

The world famous Royal Society is a purveyor of the Global Warming hoax!

Many of the famous fellows of this society are probably spinning in their graves. E.g. Isaac Newton, Charles Darwin, Michael Faraday, Ernest Rutherford, Srinivasa Ramanujan, Albert Einstein  and many others!

Just take the first two sentences:
"The Sun serves as the primary energy source for Earth’s climate. Some of the incoming sunlight is reflected directly back into space, especially by bright surfaces such as ice and clouds, and the rest is absorbed by the surface and the atmosphere."
The Royal Society wants us to believe that we know everything about the sun and that the sun and its radiation never changes! Both is total nonsense!

Climate change: evidence and causes | Royal Society: Supplementary information for the project 'Climate Change: Evidence and causes'.