Doctors try 1st CRISPR editing in the body for blindness

Good news!

"The gene-editing tool CRISPR has been used for the first time inside the body of an adult patient, in an attempt to cure a form of blindness.  

The treatment: According to the Associated Press, doctors dripped just a few drops of a gene-editing mixture beneath the retina of a patient in Oregon who suffers from Leber congenital amaurosis, a rare inherited disease that leads to progressive vision loss. Cells that take up the mixture can have their DNA permanently corrected, potentially restoring a degree of vision." (Source)

Doctors try 1st CRISPR editing in the body for blindness: Scientists say they have used the gene editing tool CRISPR inside someone's body for the first time, a new frontier for efforts to operate on DNA, the chemical code of life, to treat...

First Patient Receives In Vivo CRISPR Editing | The Scientist Magazine®: Doctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy.

Super-precise CRISPR tool enhanced by enzyme engineering

Good news! CRISPR is becoming crisper!

"A super-precise version of the CRISPR genome-editing tool just got even better. Researchers have boosted the accuracy of a technique based on the popular but error-prone CRISPR–Cas9 system by engineering enzymes that can precisely target DNA without introducing as many unwanted mutations."





Super-precise CRISPR tool enhanced by enzyme engineering: Improvements to a method known as base editing could pave the way for safer gene therapies.