Good news!
"Nuclear magnetic resonance (NMR) could be on the brink of a renaissance among drug developers.
For decades, other techniques that assess the structure of drugs — such as X-ray crystallography and, more recently, cryo-electron microscopy — have overshadowed NMR because of its complexity and slowness.
But over the past five years, a suite of contract research organizations (which manage research for drug companies) have been founded with the aim of bringing NMR back into the limelight as the technology improves, to help drug discovery.
Meanwhile, NMR has been used to uncover a completely new conformational state in a group of proteins strongly linked with cancer progression. The newly discovered ‘invisible fold’ in kinases could help make kinase inhibitors more selective. “Conformational dynamics in drug discovery are critical and underappreciated,” ..."
Nature Briefing: Translational Research
NMR-as-you-go for drug hunters (no public access) "Craving speed and convenience, biopharma companies turn to providers with NMR know-how."
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