Even Switzerland of all places is now affected by these violent mass protests! This is unusual!
Showing posts with label Switzerland. Show all posts
Showing posts with label Switzerland. Show all posts
Sunday, November 01, 2026
Swiss Protests: Hundreds Protest Against Austerity in Zurich & Basel
Tuesday, October 20, 2026
Schweizer Pharma-Riese: Roche stoppt sämtliche neue Investitionen in Deutschland wegen Merz-Regierung
Könnte mal wieder typisch Bananenrepublik D sein!
Oder ist Roche nur ein bedauerlicher Einzelfall?
"Der Schweizer Pharmakonzern Roche stoppt sämtliche neuen Investitionen in Deutschland. Deutschlandchef Daniel Steiners wirft der Merz-Regierung vor, „sehr viel Vertrauen zerstört“ zu haben.
Auslöser ist die geplante Anhebung des Herstellerabschlags von 7 auf 15,5 Prozent ab 2027. Laufende Projekte laufen weiter – während Roche in den USA 50 Milliarden Dollar investiert. ..."
"Auslöser ist vor allem das geplante GKV-Beitragssatzstabilisierungsgesetz. Ab Januar 2027 soll der gesetzliche Herstellerabschlag für viele patentgeschützte Medikamente von sieben auf 15,5 Prozent steigen. Roche sieht darin einen Widerspruch zur politischen Zusage, Deutschland als Pharma- und Biotechnologiestandort zu stärken. ..."
Roche stoppt sämtliche neue Investitionen in Deutschland – Merz-Regierung „hat Vertrauen verspielt“ "Der Schweizer Pharmakonzern Roche hat genug! Sämtliche neuen Investitionen in Deutschland werden gestoppt. Deutschlandchef Daniel Steiners macht dafür die Gesundheitspolitik der Bundesregierung verantwortlich und wirft der Merz-Regierung vor, „sehr viel Vertrauen zerstört“ zu haben."
Monday, October 19, 2026
Swiss giant UBS considers shock call to leave Switzerland, sources say
Is the Swiss government going to make a huge mistake here?
For a very long time, Switzerland has been known for being savvy, reliable and using common sense when it comes to economic and business policies.
Saturday, October 17, 2026
Walking Robotic Hand Uses AI to Learn New Tricks
Amazing stuff!
"... Researchers from ETH Zurich have turned an off-the-shelf robotic hand into a completely self-contained robot that walks on its fingertips while using those same fingers to manipulate its environment. ..."
From the abstract:
"A walking robotic hand must use the same fingers to move its body, support its weight, and interact with the environment. We show how an anthropomorphic hand can learn these skills while retaining its finger design and position controller. Onboard power and computation make the platform self-contained.
Our reinforcement learning approach accounts for the hand's unequal fingers, with training in a simulator calibrated from hardware measurements.
In simulation, the hand moves faster with our reward formulation than with tuned rewards originally designed for quadrupeds.
On hardware, task-specific policies enable untethered crawling, steering, and fall recovery.
While supporting its own weight, the hand also executes successive keyboard commands without vision and pushes an object to targets using overhead visual feedback.
These results demonstrate a compact mobile manipulator that reuses its fingers for locomotion and interaction, without a separate locomotion mechanism."
Fingers as Legs (project on Github)
Fingers as Legs: Learning Self-Supported Locomotion and Manipulation with an Anthropomorphic Hand (preprint, open access)
Monday, September 14, 2026
Swiss government takes a Swiss Army knife to Microsoft 365 shiting to open source software
Good or bad news!
"... key takeaways
- Two Swiss government groups are moving from Microsoft 365 to openDesk.
- The Swiss Federal Chancellery and Swiss Armed Forces are moving at different paces.
- It’s mostly about protecting Swiss data from American snoopers.
...
They’re joining numerous other European government agencies, such as those in Austria, France, Germany, and Ireland, that are also cutting out Microsoft 365 and Windows in favor of open-source office suites and Linux.
..."
Sunday, September 06, 2026
Staatsquote in der Schweiz ist laut IWP deutlich grösser als gedacht
Haben sich die Schweizer schön gerechnet?
"Der Schweizer Staat dürfte in den nächsten Jahren grösser werden. Bundesrat und Parlament wollen für die Armee und die AHV mehr Geld ausgeben – und dafür die Mehrwertsteuer erhöhen. So wird wohl bald ein grösserer Teil dessen, was jährlich in der Schweiz erwirtschaftet wird, durch die Kassen des Bundes fliessen. Und dadurch wird auch die sogenannte Staatsquote zunehmen. Sie ist definiert als der Anteil der Staatsausgaben gemessen am Bruttoinlandprodukt (BIP)."
"Die Schweiz ist stolz auf ihren schlanken Staat. Das bekannteste Mass scheint ihr recht zu geben: 2023 entsprachen die Staatsausgaben 33,4 Prozent der Wirtschaftsleistung.
Nach Irland war das der zweittiefste Wert Europas. Auch über die Zeit blieb diese Staatsquote bemerkenswert stabil.
Ein neues Policy Paper ... zeigt, dass hinter der tiefen Staatsquote mehr staatliche Dynamik steckt, als sie vermuten lässt. ...
Das BIP umfasst allerdings auch Abschreibungen, also den Wertverlust von Maschinen, Gebäuden und Software. Dieser Teil der Wirtschaftsleistung wird benötigt, um den bestehenden Kapitalstock zu erhalten, und steht daher weder dem Staat noch Privaten für zusätzliche Ausgaben zur Verfügung. Zieht man die Abschreibungen vom BIP ab, erhält man das Nettoinlandsprodukt (NIP). Der deutsche Finanzwissenschafter Prof. Dr. Alfons Weichenrieder hat jüngst gezeigt, wie stark die Wahl zwischen BIP und NIP das Bild verändern kann ...
Für die Schweiz macht dieser Wechsel des Massstabs einen besonders grossen Unterschied: Die Abschreibungen entsprechen hier 23,4 Prozent des BIP, dem zweithöchsten Wert im EU/EFTA-Vergleich. ...
Was hinter den ausgeglichenen [öffentlichen] Haushalten steckt
Neben der tiefen Staatsquote gelten auch die seit der Jahrtausendwende meist ausgeglichenen öffentlichen Haushalte als Beleg für die Schweizer Ausgabendisziplin. Doch die Entwicklung von Ausgaben und Einnahmen zeigt, wie dieser Ausgleich zustande kam.
Die Ausgabenquote blieb zwischen 1995 und 2024 mit 33,4 beziehungsweise 33,6 Prozent nahezu unverändert.
Die Einnahmenquote stieg im selben Zeitraum hingegen von 31,5 auf 34,2 Prozent. Der Haushaltsausgleich kam damit vor allem über höhere Einnahmen zustande. ..."
Tuesday, September 01, 2026
Friday, August 21, 2026
Optimised, updated Free trade agreement Switzerland - China (SECO) in August 2026
Good or bad news! Something to watch!
It appears, this update is quite a success for Switzerland. However, it may deepen dependence!
Caveat: I am not familiar with this FTA nor with the current update
"President Guy Parmelin and Chinese Minister of Commerce Wang Wentao announced on 20 August, during a meeting in Bern, that negotiations on the optimisation of the free trade agreement (FTA) between Switzerland and the People’s Republic of China had been concluded.
Switzerland has achieved its negotiating objectives.
Under the existing FTA almost all Chinese imports into Switzerland are duty-free, while this is only the case for around half of Swiss exports to China.
The optimised FTA rectifies this imbalance: 99.8 per cent of Switzerland’s current exports will be able to enter the Chinese market duty-free. ...
Lastly, the provisions on environmental issues and labour rights will also be expanded and strengthened in the revised FTA. ..."
"... Trade between the two countries has expanded from 31.7 billion francs in 2015 to 51.2 billion francs last year, according to figures from the Swiss customs office, with China a big market for Swiss chemicals, pharmaceuticals, precision instruments and watches. ..."
Monday, August 17, 2026
Planet Venus may be geologically active
Amazing stuff! This was discovered on NASA images from the 1990s? What took so long?
Do we need a new Venus mission?
"... New research shows our planetary neighbor may be less dormant than thought. Scientists reanalyzed rift valleys on Venus’s surface, which are low-lying regions formed as the crust pulls apart or due to volcanic activity. On Venus, rift valleys can span as long as 10,000 kilometers ...
High-resolution computer models of the underlying geological processes revealed that broad ridges called rift flanks form at the valleys’ edges when they are either young or still forming. Soon after, the rift flanks widen and flatten as Venus’s crust relaxes. When the researchers looked at images of the venusian surface taken by NASA’s Magellan spacecraft in the 1990s, wide, high flanks were visible. The features indicate that the surface was active somewhat recently—and the world is far from dead. ..."
"In brief
- ETH researchers have developed innovative computer models to study the rift valley systems on Venus.
- The simulations indicate that recently formed rift valleys feature high, broad flanks, whereas older valleys tend to subside and are less elevated.
- The new findings can help us identify geologically active regions that require particularly close examination for future Venus missions.
..."
From the abstract:
"Rifts are prominent tectonic features on Venus, yet their formation, evolution and tectonic activity remain debatable.
Here we conducted 3D numerical thermomechanical experiments with visco-elasto-plastic compressible rock rheology to systematically investigate the rifting dynamics and topography under Venusian conditions. To compare active and inactive rift morphologies, the relaxation of rift topography after extension ceases was also investigated.
Our modelling results suggest a relatively thick thermal lithosphere and a strong crust with dry diabase or mafic granulite rheology in rifted regions and demonstrate that wide rift flank uplifts strongly indicate either presently ongoing Venusian rifting or activity within the past few tens of millions of years.
The rift valleys in the Ganis, Dali and Devana Chasmata have wide rift flank uplifts, and their characteristic topographic features are comparable to the modelled early-stage active rifts undergoing relatively high extension rates of 3−10 cm yr−1.
This suggests that the Venus rifts in these regions are still active or were active very recently. Their morphology also indicates faster extension rates than commonly assumed for Venusian rifting, potentially associated with recent vigorous mantle plume activity."
Venus: Dead? Far from it (original news release) "Simulations conducted by researchers at ETH Zurich suggest a strong likelihood that Venus’s rift valleys are still geologically active rather than being mere relics of a bygone era, as had been previously believed. This finding reshapes our understanding of Earth’s sister planet and will influence future missions to Venus. "
There are huge rift valleys on Venus. They suggest that the planet is still geologically active.
Thursday, July 30, 2026
US Added 1,200 Millionaires a Day Last Year for a total of 441,078 new millionaires or almost half of all new millionaires worldwide
Good news! Good times!
How many of them were lottery game winners? 😊 [Few, I guess.]
"The United States added 441,078 new millionaires last year, more than 1,200 every day, according to global wealth data. There are now 23.6 million American millionaires, more than two of every five worldwide.
Global personal wealth rose 10.8% in 2025, and nearly 1 million people worldwide joined the ranks of millionaires. Every one of the 56 markets tracked ended the year with more millionaires than it started. ..."
"... Adults in North America remained the wealthiest on average, with average wealth per adult of USD 660,000, followed by Australia and New Zealand at almost USD 590,000, while Western Europe reached over USD 330,000.
Switzerland continued to top the ranking for average wealth per adult at USD 910,382, followed by the United States and Luxembourg ...
The United States accounted for almost half of newly created millionaires in 2025, adding more than 440,000 individuals, followed by mainland China, Japan, Germany, the United Kingdom, and France, each counting over 2 million millionaires in total. ..."
Global Wealth Report 2026: Global wealth rose over 10% in 2025 (original news release) "In 2025, global wealth expanded at its fastest pace since 2017, marking the third consecutive year of growth. The latest edition of the UBS Global Wealth Report shows a broad-based increase in personal wealth, driven by strong financial markets and rising non‑financial assets, with average wealth growing faster than global economic output. However, gains were uneven, with differences across regions and wealth segments."
Monday, July 27, 2026
Destruction of male chicken eggs pain free before hatching is about to spread worldwide
Good news! Don't feel so guilty anymore when eating chicken meat, soup or eggs! 😊
"In-ovo sexing is a hatchery technology that determines the sex of a chicken embryo inside an egg using optical, fluid-biomarker, or MRI methods between days 8 and 13 of incubation." (Google Search)
"Today, throughout much of the chicken egg industry, newly hatched male chicks—economically useless because they neither lay eggs nor grow efficiently for meat—are gassed or thrown into industrial grinders.
That horror may come to an end thanks to in-ovo sexing, a relatively new technique that allows hatcheries to cheaply identify and destroy male chicken embryos before they are capable of feeling pain.
According to a recent report from Innovate Animal Ag, an animal agriculture think tank, 40 percent of Europe’s commercial laying flock had been sexed in ovo as of June 2026, up from 34 percent in 2025. ..."
"Summary ...
- 40% of the EU’s commercial egg layer flock was sexed with in-ovo technology–a 6-point penetration increase from April 1, 2025.
- Since 2021, over 281 million male embryos have been removed before hatching globally.
- In Europe, in-ovo sexing technology has reached a production rate of 100 million female chicks per year, climbing from 500k chicks per month in 2021 to well over 8 million female chicks per month by the publication of this report, a CAGR of over 75%.
- In-ovo sexing is beginning its market-based rollout in the US with over 4% of the country’s commercial layer flock having publicly announced a transition to use the technology as existing flocks are retired.
- In Switzerland, where in-ovo sexing technology kicked off in 2025, in-ovo sexing penetration climbed rapidly and now sits at around 85 to 100% of the country’s layer flock. In Norway, in-ovo sexing has hit a 52% market penetration.
- The global penetration of in-ovo sexing is forecasted to continue its sharp growth in the next few years, led by expansion in the US, continued strength in Europe as a consequence of Italy’s ban on male chick culling, growth in markets where the technology has recently entered such as Australia and Brazil, and potential penetration into greenfield markets like Canada and China.
..."
Sunday, July 12, 2026
First 3D Structure of Inactivated Cone Opsins Revealed in three different studies
Amazing stuff! I limit myself here to one of the three papers.
"... In a new study, ... two researchers ... have succeeded for the first time in determining the three-dimensional structure of human cone opsins in their dark state and showing how their molecular architecture enables their rapid activation by light. This provides important new insights into human vision and its evolution and may offer new starting points for the study of eye diseases that currently lack effective treatment. ..."
From the editor's summary and abstract:
"Editor’s summary
Human daytime vision relies on a trio of visual receptors called opsins, which are found in the cone cells in and around the central region of the retina.
The three opsins are tuned to long, medium, or short wavelengths of light, roughly corresponding to red, green, and blue, and mutations or other defects in cone cell function can lead to vision deficits.
Although the cell biology and biochemistry of color vision have been well studied, up to now, the molecular explanation for cone opsin spectral tuning and signaling kinetics has been limited by a lack of experimental structures.
Three papers in this issue now resolve this deficit.
Schmidt et al. determined structures of the dark state of the green and blue human cone opsins, which revealed important details of these receptors and provide a basis for a femtosecond-resolution spectroscopy study.
Ohashi et al. performed complementary structural, spectroscopic, and computational results with dark-state red and green cone opsins from macaques, which have color vision similar to humans.
Finally, Peng et al. studied all three human cone opsins in the presumed active state bound to a G protein and all-trans retinal.
The three papers together provide a clear picture of the features of these visual receptors that lead to different spectral properties, activation and inactivation kinetics, and recycling. ...
Structured Abstract
INTRODUCTION
High-acuity daylight vision relies on cone photoreceptors, specialized class A G protein–coupled receptors (GPCRs). Like other light-sensitive GPCRs, the three human cone opsins covalently bind vitamin A derivative 11-cis-retinal through a protonated Schiff base. Despite sharing the same chromophore, they detect distinct wavelengths of light and generate swift signaling responses at high repetition rates. Although cone opsins are central to human vision, and in contrast to the well-studied rod photoreceptor rhodopsin, the detailed molecular basis of these functional specializations remains elusive.
RATIONALE
To obtain structure-function relationships that extend the kinetic and mechanistic understanding of photopic vision, we solved cryo–electron microscopy (cryo-EM) structures of the two most evolutionarily and functionally divergent human cone opsins, short-wavelength-sensitive OPN1SW and medium-wavelength-sensitive OPN1MW, in their initial 11-cis-coupled state. We combined the structural data with multiple functional assays, hybrid quantum mechanics/molecular mechanics simulations, time-resolved spectroscopy, and multitaxon opsin sequence analysis.
RESULTS
Cryo-EM structures of cone opsins revealed receptor-specific activation mechanisms and distinct strategies for stabilizing the retinal Schiff base.
OPN1SW, representing the phylogenetically older vertebrate opsins, has a more constrained polar chromophore environment, which contributes to its blue-shifted maximum absorption wavelength (λmax), yet its stabilization is weaker than that of rhodopsin. The architecture of OPN1SW shows substantial divergences in the canonical GPCR microswitch networks, including the replacement of the toggle switch with Y6.48, a disrupted PIF triad, and the absence of a highly conserved sodium- or water-coordination site.
Collectively, these alterations favor a preactive conformation, also captured by cryo-EM. OPN1SW further uses W185ECL2 as a steric switch to transmit the retinal isomerization event across several helices through an extended aromatic network.
In contrast, OPN1MW contains a chloride ion within the chromophore-binding pocket that modulates wavelength sensitivity and influences the amplitude of G protein signaling. This chloride-binding site coevolved with a structural pathway on helix 2 that couples chromophore chemistry to canonical GPCR microswitches.
Both receptors have accessible binding pockets that allow rapid ligand hydrolysis and, consequently, fast retinal turnover.
Femtosecond transient-absorption spectroscopy resolved the photoisomerization cascade, supporting a model in which deprotonation and subsequent hydrolysis limit signal duration in cone opsins.
CONCLUSION
Our structural and mechanistic insights describe how distinctive chromophore environments and GPCR microswitch adaptations tune spectral sensitivity and signaling-state lifetimes in cone opsins. Conservation of central residues across short-wavelength-sensitive and medium-to-long-wavelength-sensitive opsins suggests shared mechanistic principles that shaped the evolution of daylight vision. Similar motifs in other GPCRs, including sensory receptors, inform the strategies for modulating receptor activation kinetics and signal duration."
New insights into human vision (original news release)
Experiment performed at ELI Enables New Insights into Human Vision (original news release) "The retina of the human eye contains six to seven million cone cells. These cells contain light-sensitive proteins known as cone opsins. They enable us to perceive our surroundings in detail in daylight. In a new study, researchers ... have now, for the first time, determined the three-dimensional molecular structure of human cone opsins in their dark state, that is, before they are activated by light."
Illuminating the molecular basis of human daylight vision (no public access)
Cone opsins use distinct chromophore-stabilization strategies to tune spectral sensitivity, activation kinetics, and retinal regeneration.
Thursday, July 09, 2026
Swiss researchers invented a new type of pixel that can both control and analyze light
Amazing stuff! This could be a breakthrough!
"Swiss researchers at ETH Zurich invented a new type of pixel that can both control and analyze light, a breakthrough that could dramatically improve digital photography."
"In brief
- Pixels create images on screens or capture them in cameras. Until now, however, there have been no pixels that could do both.
- Researchers have now developed a new kind of pixel that can both create and analyse images and patterns.
- In the future, these pixels could be used to realise two-way camera–displays.
In 1927, the term „picture element“, later abbreviated to „pixel“, appeared for the first time in the American technology magazine Wireless World. ...
These pixels can both steer light and analyse it. Not only the intensity of the light, but also its oscillation phase and polarisation can be controlled and analysed. ...
Patters and images from overlapping light waves
The new results ... are based on a fundamental physical effect: the so-called interference of light waves. When light is scattered by a surface, the waves originating from different points on the surface overlap. The shape of the surface determines the oscillation phases with which the waves propagate further. If the phases are equal, the light waves reinforce each other, but if they are opposed, the waves cancel out. ...
use this effect to precisely control light with wave-shaped sculpted surfaces. They developed this processing method, which is precise to within a few nanometres, already a few years ago. For steering, the pixel—that is, the area on the chip where the material has been processed—first transforms the incoming light into a surface wave (a so-called surface plasmon polariton) propagating along the surface of the chip.
At a different position within the pixel, the surface wave is scattered back out of the material as a light wave. Through interference of the light waves, patterns and images can be created. Using mathematical Fourier analysis, the researchers can calculate what these images will look like and what kind of surface pattern is needed for a specific image. ...."
From the abstract:
"Digital cameras and displays use picture elements (pixels) that perform a single function: detecting or emitting light intensity. To exploit the full information content of electromagnetic waves, more advanced elements are required. This has driven the development of multifunctional components that, for example, simultaneously detect and emit intensity or extract intensity and spectral information.
However, no pixel exists that both senses and generates optical wavefronts with full control over amplitude, phase and polarization, limiting bidirectional control and feedback of sophisticated light fields.
Here we present a route to such pixels by demonstrating a versatile platform of miniaturized diffractive elements based on Fourier optics.
We use plasmonic surface waves, which propagate coherently and efficiently across metallic surfaces. When these plasmons are launched towards wavy microstructures designed with simple Fourier analysis, arbitrary and background-free optical wavefronts are generated. Conversely, incoming light can be sensed, and its amplitude, phase and polarization can be fully characterized.
By combining or superposing several such components, we create multifunctional ‘Fourier pixels’ that provide compact and accurate control over the optical field. Our approach, which we extend to photonic waveguide modes, establishes a scalable, universal architecture for vectorially programmable pixels with applications in adaptive optics, holographic displays, optical communication and quantum information processing."
Researchers in Switzerland invent a new type of pixel "Pixels either control light or analyze it. This one does both."
A new type of pixel (original news release) "Researchers at ETH Zurich have developed pixels that can not only create images, but also analyse them. In the future, this could lead to the development of devices that function as camera and display at the same time."
Fourier pixels for bidirectional light control (open access)
The coloured logo was created using the new ETH researchers‘ Fourier pixels. The letter “E” is roughly 1 millimetre tall on the camera.
Fig. 1: Fourier pixels for generating light with arbitrary amplitude and phase.
Wednesday, June 03, 2026
Vierbeinige Roboter „Anymal“ des Schweizer Robotic-Start-ups Anybotics
Die Roboter kommen! Auf den Hund gekommen! Sehr animalistisch!
"Er läuft Patrouille in Umspannwerken, Gasanlagen und Stahlhütten. Er kann Treppen erklimmen und sogar 3D-Modelle der Anlagen erstellen, die er inspiziert. Die Rede ist von einem neuartigen Tier, das die Natur so nicht vorgesehen hatte – dem künstlichen Hund.
Der rot-graue Vierbeiner „Anymal“ des Schweizer Robotic-Start-ups Anybotics ist keine Zukunftsvision, sondern Alltag, schreibt das Handelsblatt. Der Roboter wird bereits weltweit eingesetzt, teilweise gibt es für ihn sogar Hundenamen und Hundehütten.
„Wir haben inzwischen mehrere Hundert Roboter in Betrieb, die pro Tag zwei bis acht Stunden arbeiten“, sagt Firmenchef Peter Fankhauser. Zu den Anybotics-Kunden gehören der Industriekonzern Siemens und das brasilianische Bergbauunternehmen Vale. ..."
Welcher Robotertyp überzeugt in Unternehmen "Zweibeinige Roboter stehlen den „Robodogs“ zwar die Show. Doch vierbeinige Modelle werden Experten zufolge bisher viel häufiger eingesetzt. Branchenkenner erwarten ein enormes Marktwachstum."
Anybotics-Chef Fankhauser: Der Firmengründer mit seinen vierbeinigen Anymals.
Friday, May 29, 2026
Unprecedented view inside live stem cells reveals aging process and loss of regenerative capacity
Amazing stuff!
"Scientists have developed a powerful new technique that allows them to observe how individual cells manufacture proteins during aging, offering an unprecedented glimpse into the hidden molecular activity of stem cells in living tissue. ...
What scientists saw was the intricate choreography within stem cells and how those molecular dance steps slow and change with age. The team of Swiss scientists has concluded that the process of aging reshapes how skin stem cells manufacture proteins. ..."
From the highlights and abstract:
"Highlights
• In vivo single-cell ribosome profiling monitors tissue-wide translational landscapes
• RNase I-generated footprints reveal robust triplet periodicity in vivo
• Tissue-wide mapping of translational efficiencies across epidermal cell types
• Aging drives selective translational induction of AP-1 subunits in stem cells
Summary
Somatic stem cells are characterized by their low overall protein-synthesis rates, a feature implicated in driving their stemness. However, how aging reshapes the translational landscape of stem cells remains poorly understood.
Here, we present an in vivo single-cell ribosome profiling strategy to monitor tissue-wide translational landscapes of the epidermis during aging.
By implementing ribosomal elongation-inhibited cell isolation and switching to RNase I, we expand the applicability of single-cell ribosome profiling to in vivo systems and facilitate the evaluation of triplet periodicity, a hallmark of high-quality data.
Leveraging this strategy, we document the in vivo translational landscapes of the major epidermal cell types, outline cell-type-specific translational efficiencies, and identify a pronounced translational reprogramming of AP-1 subunits specifically in aged epidermal stem cells. Our study illustrates the power of in vivo single-cell ribosome profiling to map cell-type-specific translational programs and offers a scalable strategy for tissue-wide interrogation of translational landscapes."
In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging (open access)
Graphical abstract
In der Schweiz wird immer öfter mit Psychedelika behandelt
Gute Nachrichten!
Wirken die Psychedelika dauerhaft oder müssen die Psychedelika ständig eingenommen werden über Jahre etc.?
"... Stand der Forschung: Nach einem Hype in den 1960er Jahren wurde die Forschung an Psychedelika aufgrund des amerikanischen «War on Drugs» komplett eingestellt und erst in den 2000er Jahren wieder aufgegriffen. Heute gehört die Schweiz zu den Vorreitern in der Forschung.
- In Ausnahmefällen erlaubt: In der Schweiz können Patienten seit 2014 eine Bewilligung für die Therapie mit Psychedelika bekommen. In Deutschland ist 2025 eine ähnliche Regelung in Kraft getreten. Bedingung: Andere Therapien blieben erfolglos.
- Das zeigen Studien: Vor kurzem wurden die Ergebnisse einer der bisher grössten Studien publiziert. Die Forscher untersuchten 144 Probanden. Wer Psychedelika erhielt, war sechs Wochen später signifikant weniger depressiv als die Probanden in der Kontrollgruppe.
- Mehr als nur Depressionen: Es gibt Hinweise darauf, dass Psychedelika auch gegen Sucht, posttraumatische Belastungsstörung und Ängste am Lebensende wirken können.
..."
Thursday, May 28, 2026
Swiss national Attacker wounds three with knife in Switzerland reportedly shouts 'Allahu Akbar'
Even Switzerland appears not to be spared from such Islamist fanatic terrorists!
Wednesday, May 20, 2026
Four German speaking European countries tout pan-German space command amid European push to supplant US tech
Good news! Europe ought to form their own defense organisation like NATO!
"Germany’s defense minister used a rare four-nation gathering of German-speaking defense chiefs this week to push forward plans for a European military space command, calling on close partners including Austria, Switzerland and Luxembourg, to help shape the initiative rather than simply join it.
Boris Pistorius, Germany’s defense minister, announced at a press conference in Berlin that Germany is developing a European Space Component Command alongside a Weltraumakademie − a multilateral space training academy − and insisted that partner nations will be “embedded in the design phase” rather than presented with finished structures.
The meeting, billed as the first “DACH+L” format, expanding the traditional German-Austrian-Swiss defense dialogue to include Luxembourg, served as a platform for Pistorius to demonstrate traction on Germany’s €35 billion ($40.7 billion) military space investment pledged last fall. That program spans encrypted low-earth-orbit satellite constellations, military-grade launch capacity, and an expanded Space Command within the Bundeswehr.
Austria’s Defense Minister Claudia Tanner reaffirmed that Austria plans to put three operationally designated military satellites plus a test object into orbit next year, developed partly with Austrian startups."
Austria’s Defense Minister Claudia Tanner (Source)
Tuesday, March 24, 2026
Ein Schweizer Unternehmer findet Fälschungen seines Garns auf Temu
«In China kopiert man Rolex oder Louis Vuitton – und jetzt Lang Yarns»
Jakob Lang verkauft Handstrickgarne in sechster Generation. Kann er den chinesischen E-Commerce überleben? Quelle
Thursday, February 12, 2026
Switzerland to Vote in referendum on Capping Population at 10 Million with Palki Sharma
Palki's arguments are screwed up in more than one way! Switzerland is a small, wealth country. Thus a 10 million population limit is not a bad idea! No the population will not shrink! Switzerland is too attractive!
I think, Palki is not familiar with robots who will assist an aging population!
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