A woman’s genetic mutation may hold the key to stopping Alzheimer’s

Good news! Very recommendable! Fascinating research!

Thanks to a family in Medellin, Colombia we know now much more about Alzheimer's. "The Colombian family, 5,000 members strong, includes an estimated 1,000 or so people who carry the Paisa mutation in the presenilin 1 gene. "

"Perhaps this unusually resilient woman in Colombia shows a way to halt the disease, or at least slow it down."

"This pileup [of amyloid] is already visible in brain scans of people in their 20s who carry the mutation. By their mid-40s, many of these people have trouble remembering; they typically develop full-blown dementia by age 50.

Inheriting just one copy of the mutation is enough to lead to excess amyloid, and ultimately dementia."

A woman’s genetic mutation may hold the key to stopping Alzheimer’s | Science News: A single mutation in a woman who evaded Alzheimer’s may point to new ways to treat the disease.