Wednesday, August 17, 2022

Blood abnormalities found in people with Long Covid. Really!

Long Covid is the latest obsession, alarmism, and hysteria of the medical profession! 

Let's not forget for one moment that Covid-19 is big business! Plus, Covid-19 is overall a fairly harmless disease compared to plagues of the  past!

It is so easy to explain all kinds of medical conditions by pointing to a previous Covid-19 infection! Like any weather condition is now automatically blamed on Climate Change.

What they don't tell you e.g. is what was the status or health condition of the patients before they contracted Covid-19? These studies rely on so called control groups, but not on the actual history of the affected patients itself.

They also mention some anecdotal evidence, like a patient's self reported "that their once-normal gym workouts were too exhausting to resume.". This is not hard evidence!

From the abstract:
"SARS-CoV-2 infection can result in the development of a constellation of persistent sequelae following acute disease called post-acute sequelae of COVID-19 (PASC) or Long COVID1–3. Individuals diagnosed with Long COVID frequently report unremitting fatigue, post-exertional malaise, and a variety of cognitive and autonomic dysfunctions; however, the basic biological mechanisms responsible for these debilitating symptoms are unclear. Here, 215 individuals were included in an exploratory, cross-sectional study to perform multi-dimensional immune phenotyping in conjunction with machine learning methods to identify key immunological features distinguishing Long COVID. Marked differences were noted in specific circulating myeloid and lymphocyte populations relative to matched control groups, as well as evidence of elevated humoral responses directed against SARS-CoV-2 among participants with Long COVID. Further, unexpected increases were observed in antibody responses directed against non-SARS-CoV-2 viral pathogens, particularly Epstein-Barr virus. Analysis of circulating immune mediators and various hormones also revealed pronounced differences, with levels of cortisol being uniformly lower among participants with Long COVID relative to matched control groups. Integration of immune phenotyping data into unbiased machine learning models identified significant distinguishing features critical in accurate classification of Long COVID, with decreased levels of cortisol being the most significant individual predictor. These findings will help guide additional studies into the pathobiology of Long COVID and may aid in the future development of objective biomarkers for Long COVID."

Blood abnormalities found in people with Long Covid | Science | AAAS Study implicates lack of key hormone, battle-weary immune cells, and reawakened viruses

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