Amazing stuff!
"For the first time, an artificial molecular motor has been created that can ‘talk’ to living cells – by gently pulling their surface with enough physical force to elicit a biochemical response. The approach could help scientists decode the language that cells use to communicate with each other in tissues. ...
‘Ultimately, we want to be able to provide signals to cells and guide their function when they are not able to do that by themselves in disease cases.’ ...
‘Ultimately, we want to be able to provide signals to cells and guide their function when they are not able to do that by themselves in disease cases.’ ...
with alkene-based molecular motors that use energy from ultraviolet (UV) light to delicately pull on cell membranes with tiny amounts of force and trigger a biochemical response.
The motors comprise a stator and a rotor part, out of which protrude four polyethylene glycol arms. ...""... Inspired by cellular mechanisms for force application (i.e. motor proteins pulling on cytoskeletal fibers), we present a unique molecular machine that can apply forces at cell-matrix and cell-cell junctions using light as an energy source. The key actuator is a light-driven rotatory molecular motor linked to polymer chains, which is intercalated between a membrane receptor and an engineered biointerface. ..."
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