Saturday, June 27, 2020

Huntington’s disease progression involves DNA damage sensor

Good news! We may be getting closer to a cure!



"A new study ... provides new insights into the molecular events that lead to the progressive destruction of brain cells in Huntington’s. The research reveals a central role for a damage-sensing enzyme called cGAS that seems to ignite a cascade of inflammation and excessive cellular housekeeping, a process called autophagy. Their study, a ... raises the possibility that reducing cGAS activity in the brain may be a treatment strategy worth testing in further studies ..."



Huntington’s disease progression involves DNA damage sensor | Scripps Research Abnormal cellular housekeeping and inflammation point to potential target for treating fatal neurodegenerative disorder.

No comments: