Tuesday, November 03, 2020

New Tracer Gives Clear Picture of Alzheimer's and Other Dementias

Good news!

"The tracing agent, which highlights the accumulation of toxic tau protein deposits in the brain, could distinguish between a range of conditions called tauopathies that can be difficult to tell apart at the early stages, such as frontotemporal dementia and progressive supranuclear palsy. ...
The new tracer, known as 18F-PM-PBB3, carries a radioactive fluorine isotope to the tau tangles and releases a positron particle detected by a PET scanner when it binds its target. ... their tracer also had the unexpected effect of binding to a greater variety of tau deposits seen across different tauopathies. This means that the same tracer could be used as a diagnostic test for multiple neurodegenerative conditions."

New Tracer Gives Clear Picture of Alzheimer's and Other Dementias | The Scientist Magazine® An imaging agent reveals aggregated tau protein in the brain during PET scans and could improve the diagnosis of neurodegenerative diseases, particularly tauopathies.

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