Rockfish, which range in longevity from 11 to over 205 years, Hold Clues to Human Longevity in their genes

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"... Some rockfish species can live to be 200 years old, making them some of the longest-living animals on Earth. Researchers ... combed through nearly two dozen rockfish (genus Sebates) genomes, finding genes associated with increased longevity. These genes, the researchers found, are also correlated with increased human longevity, and could one day help researchers better understand or even prevent age-related diseases. ...
The team also found that a number of genes involved in flavonoid metabolism evolved alongside longevity. ...
By analyzing a large human genome sequencing database, they found that genetic variation in flavonoid metabolism genes was also linked to longer lifespans and survival in people. ..."

From the abstract:

"Longevity is a defining, heritable trait that varies dramatically between species. To resolve the genetic regulation of this trait, we have mined genomic variation in rockfishes, which range in longevity from 11 to over 205 years. Multiple shifts in rockfish longevity have occurred independently and in a short evolutionary time frame, thus empowering convergence analyses. Our analyses reveal a common network of genes under convergent evolution, encompassing established aging regulators such as insulin signaling, yet also identify flavonoid (aryl-hydrocarbon) metabolism as a pathway modulating longevity. The selective pressures on these pathways indicate the ancestral state of rockfishes was long lived and that the changes in short-lived lineages are adaptive. These pathways were also used to explore genome-wide association studies of human longevity, identifying the aryl-hydrocarbon metabolism pathway to be significantly associated with human survival to the 99th percentile. This evolutionary intersection defines and cross-validates a previously unappreciated genetic architecture that associates with the evolution of longevity across vertebrates."

Rockfish Genes Hold Clues to Human Longevity | The Scientist Magazine®

Convergent genomics of longevity in rockfishes highlights the genetics of human life span variation (open access)

Fig. 3. Convergent rate analysis reveals specific genes and gene sets under convergent evolution with rockfish longevity