Wednesday, June 28, 2023

Beyond Ozempic: brand-new obesity drugs will be cheaper and more effective

Amended 7/6/2023: However, in many cases the best, most efficient, and cheapest treatment is more self discipline, better and less food, and more physical exercise!

Good news!

"Two new drugs for treating obesity are on course to become available in the next few years — and they offer advantages beyond those of the highly effective blockbuster drugs already on the market. The first, called orforglipron, is easier to use and to produce, and it will probably be cheaper than existing treatments. The second, retatrutide, has an unprecedented level of efficacy, and could raise the bar for pharmacological obesity treatment. ...
Orforglipron and retatrutide both mimic hormones produced by the lining of the gut in response to certain nutrients. These hormones help to slow the passage of food through the digestive tract and lower appetite by acting on receptors in the brain — both effects that reduce people’s desire to eat and help them to lose weight.  ...
retatrutide could provide an unprecedented level of weight loss. At the highest dose used in the trial, participants lost an average of 24.2% of their body weight over 11 months of treatment. Currently approved drugs tend to yield around 15–20% weight loss over a similar time period. ..."

Beyond Ozempic: brand-new obesity drugs will be cheaper and more effective Hormone mimics offer advantages even beyond those of the potent weight-loss jabs on the market now.

Your next Halloween costume? 😊 Maybe not! The lipid-storage cells called adipocytes (orange; artificially coloured) enlarge during the development of obesity


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