Bodybuilding supplement promotes healthy aging and extends life span, at least in mice

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"“The big thing about this is that its safety profile is so good,” says University of North Dakota aging researcher Holly Brown-Borg ... The molecule grabbed attention as a possible antiaging treatment in 2014, when researchers reported AKG could extend life span by more than 50% in tiny Caenorhabditis elegans worms. That’s on par with a low-calorie diet, which has been shown to promote healthy aging, but is hard for most people to stick with. ... Some differences jumped out within a few months: “They [mice] looked much blacker, shinier, and younger” than control mice ... In addition, the AKG-fed mice scored an average of more than 40% better on tests of “frailty,” as measured by 31 physiological attributes including hair color, hearing, walking gait, and grip strength. And female mice lived a median of 8% to 20% longer after AKG treatment began than control mice, "

Bodybuilding supplement promotes healthy aging and extends life span, at least in mice | Science | AAAS