Wednesday, October 16, 2019

Voltage gated calcium channels 'read' electric patterns in embryos to create cartilage and bone

Amazing stuff!


Voltage gated calcium channels 'read' electric patterns in embryos to create cartilage and bone: Scientists at Allen Discovery Center at Tufts University and Harvard Medical School have revealed how, in the case of limb formation, the electrical patterns formed within an embryo initiate a cascade of molecular changes that culminate in the development of cartilage and bone. The study, published today in Proceedings of the National Academy of Sciences (PNAS), helps answer a central question in developmental biology: "How do immature cells in the developing embryo differentiate and organize into a body?"

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