Thursday, January 26, 2023

Doomsday Clock closest to global catastrophe - Bulletin of the Atomic Scientists

News sources remind us these days that "The Clock now stands at 90 seconds to midnight—the closest to global catastrophe it has ever been."

Some scarecrows never die!


As if the medieval ages never went away! This is almost comical!

For how many decades has this or similar doomsday clocks been around? How many times has this scare been used? Apparently, since 1947 (see screen shot below)!

Don't pee in your pants yet!

Doomsday Clock - Bulletin of the Atomic Scientists






Poet Eliza Snow, the plural wife of prophets who fought for polygamy, women

I like that headline!

Is it not curious that the LGBTQ community does not embrace polygamy/polyandry? It is actually very curious omission!

"Eliza R. Snow — poet, preacher, president and plural wife of prophets Joseph Smith and Brigham Young — was a staunch defender of polygamy.
“She spoke about the curse of Eve and overcoming the fall through plural marriage,” historian Jennifer Reeder said ..."

"Eliza Roxcy Snow (January 21, 1804 – December 5, 1887) was one of the most celebrated Latter Day Saint women of the nineteenth century. A renowned poet, she chronicled history, celebrated nature and relationships, and expounded scripture and doctrine. ..."

"... “Do you know of any place on the face of the earth,” she asked in 1870, “where woman has more liberty, and where she enjoys such high and glorious privileges as she does here, as a Latter-day Saint?” [Maybe there is a kernel of truth in this statement]  ...
Her obituary in the New York Times described her as “one of the central figures of the Mormon galaxy.” ..."

‘Mormon Land’: Historians discuss poet Eliza Snow, the plural wife of prophets who fought for polygamy, women

Eliza R. Snow (Source: The Church of Jesus Christ of Latter Day Saints)

Wednesday, January 25, 2023

Who Is Volodymyr Zelenskiy Really?

Very recommendable!

Tucker Carlson: This is scary! Many questions about Jeffrey Epstein's death or murder

Very recommendable! Who killed Jeffrey Eppstein? Was it a fellow prisoner? It appears fellow prisoners in the same tract had access to Eppstein's cell.

Microsoft and OpenAI extend partnership through a multiyear, multibillion dollar investment

This is a huge announcement with great potential! Two top companies in the AI & machine learning arena get closer together!

"Today [1/23/2023], we are announcing the third phase of our long-term partnership with OpenAI through a multiyear, multibillion dollar investment to accelerate AI breakthroughs to ensure these benefits are broadly shared with the world."

Microsoft and OpenAI extend partnership - The Official Microsoft Blog

On Transformer models: an introduction and catalog

Recommendable! Nice overview with time lines, family trees, explanations etc.

Transformer models: an introduction and catalog — 2023 Edition - AI, software, tech, and people, not in that order… by X

China steps up approvals for foreign financial companies including a majority of U.S. companies

This could be big news and a game changer! A communist country is opening up to foreign financial companies!

"China has issued a flurry of approvals for foreign financial companies looking to expand into the country as Beijing seeks to boost investor confidence after abruptly ending years of pandemic restrictions.
 
Most of the approvals have been in the asset management sector, a $4 trillion market in China. ..."

China steps up approvals for foreign financial companies - Nikkei Asia U.S. players account for majority of authorizations since last autumn

Google Travel Annoyances

Today, I tried to look up some flight information and here is what I got from Google Travel!

You see the second last column showing CO2 emissions for each flight! Google does not even allow you to turn off this distracting nonsense!

So I am being inundated with the Global Warming hoax and Climate Change religion by Google!



Nigeria opens new China-funded seaport in bid to drive economic growth

Good news!

Manila welcomes first batch of Chinese travellers in nearly 3 years

Good news! Chinese tourism abroad is picking up again! Other destination countries of Chinese tourism are benefiting too!

Gregorian chant

Recommendable!

Fernando Santos: Poland appoints ex-Portugal coach to become their national football coach

I would say this is highly unusual! Possibly, a great move by Poland, although Poland was in the past already a top football playing nation.

Fernando Santos: Poland appoint ex-Portugal boss as head coach - BBC Sport



Tuesday, January 24, 2023

Engineers grow “perfect” atom-thin 2D materials on industrial silicon wafers

Good news!

"... Enter 2D materials — delicate, two-dimensional sheets of perfect crystals that are as thin as a single atom. At the scale of nanometers, 2D materials can conduct electrons far more efficiently than silicon. The search for next-generation transistor materials therefore has focused on 2D materials as potential successors to silicon. ...
The team has developed a method that could enable chip manufacturers to fabricate ever-smaller transistors from 2D materials by growing them on existing wafers of silicon and other materials. The new method is a form of “nonepitaxial, single-crystalline growth,” which the team used for the first time to grow pure, defect-free 2D materials onto industrial silicon wafers. ...
With their method, the team fabricated a simple functional transistor from a type of 2D materials called transition-metal dichalcogenides, or TMDs, which are known to conduct electricity better than silicon at nanometer scales. ...
the researchers use conventional vapor deposition methods to pump atoms across a silicon wafer. The atoms eventually settle on the wafer and nucleate, growing into two-dimensional crystal orientations. If left alone, each “nucleus,” or seed of a crystal, would grow in random orientations across the silicon wafer. ... found a way to align each growing crystal to create single-crystalline regions across the entire wafer. ...
To do so, they first covered a silicon wafer in a “mask” — a coating of silicon dioxide that they patterned into tiny pockets, each designed to trap a crystal seed. Across the masked wafer, they then flowed a gas of atoms that settled into each pocket to form a 2D material — in this case, a TMD. The mask’s pockets corralled the atoms and encouraged them to assemble on the silicon wafer in the same, single-crystalline orientation. ... “You have single-crystalline growth everywhere, even if there is no epitaxial relation between the 2D material and silicon wafer.”
With their masking method, the team fabricated a simple TMD transistor and showed that its electrical performance was just as good as a pure flake of the same material.
They also applied the method to engineer a multilayered device. After covering a silicon wafer with a patterned mask, they grew one type of 2D material to fill half of each square, then grew a second type of 2D material over the first layer to fill the rest of the squares. The result was an ultrathin, single-crystalline bilayer structure within each square. ..."

MIT engineers grow “perfect” atom-thin materials on industrial silicon wafers | MIT News | Massachusetts Institute of Technology Their technique could allow chip manufacturers to produce next-generation transistors based on materials other than silicon.


By depositing atoms on a wafer coated in a “mask” (top left), ... can corral the atoms in the mask’s individual pockets (center middle), and encourage the atoms to grow into perfect, 2D, single-crystalline layers (bottom right).


Neuromorphic Memristors Run AI Tasks at 1/800th Power

Good news! Very impressive results! Brains made of silicon!

"... Now two new studies may help solve key problems these components face not just with yields and reliability, but with finding applications beyond neural nets. ...
Such brain-inspired neuromorphic hardware may also prove ideal for implementing neural networks—AI systems increasingly finding use in applications such as analyzing medical scans and empowering autonomous vehicles. ...
researchers in Israel and China fabricated memristive devices using a standard CMOS production line. The resulting silicon synapses the team built boasted a 100 percent yield with 170- to 350-fold greater energy efficiency than a high-performance Nvidia Tesla V100 graphics processing unit when it came to multiply-accumulate operations, the most basic operation in neural networks. ...
The scientists developed the new devices using the floating-gate transistor technology used in commercial flash memory. Whereas conventional floating-gate transistors have three terminals, the new components have only two. ...
The new devices displayed high endurance, operating past more than 100,000 cycles of programming and erasing by using voltage pulses. In addition, they showed only moderate device-to-device variation and are projected to possess long data retention times of more than 10 years. ...
In another study, a team of French researchers investigated using memristors for the statistical computing technique known as Bayesian reasoning, in which prior knowledge helps compute the chances that an uncertain choice might be correct. Its results are fully explainable—unlike many nearly inscrutable AI computations—and it can perform well when there is little available data, as it can incorporate prior expert knowledge. ...
The scientists rewrote Bayesian equations so a memristor array could perform statistical analyses that harnesses randomness—a.k.a. “stochastic computing.” Using this approach, the array generated streams of semi-random bits at each tick of the clock. These bits were often zeroes but were sometimes ones. The proportion of zeroes to ones encoded the probabilities needed for the statistical calculations the array performed. This digital strategy uses relatively simple circuitry compared to nonstochastic methods, all of which reduces the system’s size and energy demands.
The researchers fabricated a prototype circuit incorporating 2,048 hafnium oxide memristors on top of 30,080 CMOS transistors on the same chip. In experiments, they had the new circuit recognize a person’s handwritten signature from signals beamed from a device worn on the wrist. ..."

From the abstract (1):
"Memristors, and other emerging memory technologies, can be used to create energy-efficient implementations of neural networks. However, for certain edge applications (in which there is access to limited amounts of data and where explainable decisions are required), neural networks may not provide an acceptable form of intelligence. Bayesian reasoning could resolve these concerns, but it is computationally expensive and—unlike neural networks—does not naturally translate to memristor-based architectures. Here we report a memristor-based Bayesian machine. The architecture of the machine is obtained by writing Bayes’ law in a way that makes its implementation natural by the principles of distributed memory and stochastic computing, allowing the circuit to function solely using local memory and minimal data movement. We fabricate a prototype circuit that incorporates 2,048 memristors and 30,080 transistors using a hybrid complementary metal–oxide–semiconductor/memristor process. We show that a scaled-up design of the machine is more energy efficient in a practical gesture recognition task than a standard implementation of Bayesian inference on a microcontroller unit. Our Bayesian machine also offers instant on/off operation and is resilient to single-event upsets."

From the abstract (2):
"Memristor-based neuromorphic computing could overcome the limitations of traditional von Neumann computing architectures—in which data are shuffled between separate memory and processing units—and improve the performance of deep neural networks. However, this will require accurate synaptic-like device performance, and memristors typically suffer from poor yield and a limited number of reliable conductance states. Here we report floating-gate memristive synaptic devices that are fabricated in a commercial complementary metal–oxide–semiconductor process. These silicon synapses offer analogue tunability, high endurance, long retention time, predictable cycling degradation, moderate device-to-device variation and high yield. They also provide two orders of magnitude higher energy efficiency for multiply–accumulate operations than graphics processing units. We use two 12 × 8 arrays of memristive devices for the in situ training of a 19 × 8 memristive restricted Boltzmann machine for pattern recognition via a gradient descent algorithm based on contrastive divergence. We then create a memristive deep belief neural network consisting of three memristive restricted Boltzmann machines. We test this system using the modified National Institute of Standards and Technology dataset, demonstrating a recognition accuracy of up to 97.05%."

Memristors Run AI Tasks at 1/800th Power - IEEE Spectrum These brain-mimicking devices boast tiny energy budgets and hardened circuits

(1) A memristor-based Bayesian machine (no public access, but article above contains a link to the PDF file)







How a mother’s microbiome helps shape her baby’s development during late pregnancy and the first year of life

Recommendable! Amazing stuff! Miracles of life!

"Appearing in Cell, the study is the first to uncover large-scale “horizontal gene transfer” events between different species of maternal and infant gut bacteria. The research also revealed a wide range of chemicals produced by the bacteria, or metabolites, that are unique to the baby. Together, the findings add to a growing appreciation for the complex physiological connection between mother and infant during early life. ...
[the] lab first began studying the microbiome ... eight years ago. Since then, they have investigated how gut bacteria fluctuate during early life, how early microbiome colonization influences risk for immune-related diseases like type 1 diabetes, allergy, asthama ansd inflammatory bowel disease, and how the microbiome varies in different places around the globe.
In this new study, [the] team aimed to more deeply explore the development of the microbiome during the first year of life. They sequenced bacterial DNA from stool samples from 70 mother-child pairs collected during late pregnancy through various stages of infancy.
In the infant gut bacterial genomes, the researchers pinpointed hundreds of genes that had originated in maternal bacteria. This indicates that the bacterial horizontal gene transfer from mother to baby isn’t a one-time event at childbirth, but an ongoing process throughout the baby’s first year of life.
Among the shared genes the team identified are many that encode proteins related to the infant diet, such as enzymes that break down complex sugars in breast milk. ...
The team also revealed microbiome and metabolome profiles in the infants that were distinct from and less diverse than those in their mothers, including hundreds of unique metabolites not seen in the mothers, such as neurotransmitters and immune modulators.
In the metabolomic profiles of young, breastfed infants, the scientists found substances known to boost inflammation in disease, suggesting that in very early life, the metabolites promote healthy maturation of the immune system. ..."

From the highlights and abstract:
"Highlights
• Mobile genetic elements from maternal bacteria shape offspring gut microbiomes
• Microbiome and metabolome shifts in pregnancy may impact maternal metabolic health
• The infant gut harbors unique metabolites and species-metabolite relationships
• Diet modulates metabolomic profiles and immune system maturation in infants
Summary
The perinatal period represents a critical window for cognitive and immune system development, promoted by maternal and infant gut microbiomes and their metabolites. Here, we tracked the co-development of microbiomes and metabolomes from late pregnancy to 1 year of age using longitudinal multi-omics data from a cohort of 70 mother-infant dyads. We discovered large-scale mother-to-infant interspecies transfer of mobile genetic elements, frequently involving genes associated with diet-related adaptations. Infant gut metabolomes were less diverse than maternal but featured hundreds of unique metabolites and microbe-metabolite associations not detected in mothers. Metabolomes and serum cytokine signatures of infants who received regular—but not extensively hydrolyzed—formula were distinct from those of exclusively breastfed infants. Taken together, our integrative analysis expands the concept of vertical transmission of the gut microbiome and provides original insights into the development of maternal and infant microbiomes and metabolomes during late pregnancy and early life."

How a mother’s microbiome helps shape her baby’s development | Broad Institute


Graphical abstract


Former VP Pence informs Congress he's discovered documents in Indiana home marked classified

Are there too many classified documents being produced by the federal government?

Or are our politicians too eager to take classified documents with them?

May the next politician please come forward?

Former VP Pence informs Congress he's discovered documents in Indiana home marked classified | Just The News The Justice Department will make the final decision whether the records are classified, Pence's team said.

Bundesverfassungsgericht - Anhebung der „absoluten Obergrenze“ für die staatliche Parteienfinanzierung ist verfassungswidrig

Eine Watsche für die politischen Parteien, die sich seit einem Gesetz von 1994 frech an Steuergeldern für ihre Finanzierung bedienen!

Bundesverfassungsgericht - Presse - Anhebung der „absoluten Obergrenze“ für die staatliche Parteienfinanzierung ist verfassungswidrig

Bundesverfassungsgericht kassiert Anhebung der staatlichen Parteienfinanzierung Das höchste deutsche Gericht bremst die Parteien bei der Selbstbedienung – die letzte Erhöhung der staatlichen Parteienfinanzierung war verfassungswidrig und der Gang des Gesetzgebungsverfahrens fragwürdig. Die Parteien müssten sich auch fragen, wo sie sparen können.

Making dumplings for Chinese Spring Festival in Africa

The Chinese cuisine & culture is catching on! The way to a man's heart goes through his stomach (Old German proverb!) 😀

Utah Governor Spencer Cox Announces Lawsuit Against Social Media Companies to protect children

Wow! The Mormon-Beehive state is going against social media platforms!

Vicepresident Kamala Harris Omits “Life” from “...Liberty, and Pursuit of Happiness”...

Mistress Kamala is so bizarre! One reason, why I call her political party the Dimocratic Party! 😊 Like e.g. the 82 year old Nancy Pelosi, who has been nutty and erratic for some years!

China’s Two-Year Tech Crackdown Winds Up: What’s Changed?

Recommendable!

Egyptian President Abdel Fattah El-Sisi to be the chief guest at India's 74th Republic day parade

When two great ancient civilizations meet ...

Calvin Coolidge - One Common Country

Very recommendable!

Picture of the day

What! I almost choked when I saw this picture of Calvin Coolidge! Silent Cal! Perhaps, one of the most underrated U.S. Presidents!



Monday, January 23, 2023

Kleine modulare Kernreaktoren SMR - eine Zukunft der Energieversorgung?

Empfehlenswert! Warum ist D. eine Bananenrepublik? U.a. wegen der dümmlichen Verteufelung der Kernenergie!

Palm-sized satellites, 3D-printed rockets herald new era in space

Recommendable! Amazing stuff! Next step garbage collection in space!

"It is expected that more than 20,000 satellites for observation and communication will be launched into space within the next 10 years. A total of about 30,000 satellites, including those currently in operation, will fly above the Earth, and this is expected to revolutionize life on the ground through the use of satellite data. ...
Since successfully putting its first satellite into orbit in 2018, Rocket Lab  has successfully launched 29 times as of December 2022 and sent more than 150 satellites into space. ...There were many rockets in the process of being manufactured in the factory in Auckland, northern New Zealand. They were the company's Electron model, a small rocket for launching small satellites. The company finishes about one rocket per month. ...
With an overall length of about 18 meters and a diameter of about 1.2 meters, it is about a quarter the size of the current model of the Falcon 9 rocket (70 meters in length) of Elon Musk's SpaceX.
The cost of launching a small satellite, previously about $50 million, has been reduced to about $7.5 million. This is a major boost to space development by the private sector. Launched into Low Earth orbit (LEO) at an altitude of 2,000 kilometers or less, the Electron can carry satellites weighing up to 300 kilograms. When fully fueled before takeoff, the total weight of the rocket is about 13 tons.
Nine engines are built into the first stage of the rocket. Rocket Lab develops and manufactures its Rutherford engines, which are key components, in-house at its U.S. base.
In a world first, the company utilizes 3D printing for all major parts of the engines installed in the Electron, including the combustion chamber and pumps. In this way, it has achieved a complex and lightweight structure that was difficult to attain with conventional manufacturing technology."

Palm-sized satellites, 3D-printed rockets herald new era in space - Nikkei Asia Number of satellites to triple to 30,000 -- and change life on the ground

From the Electron rocket:


Turn the beat around: Sony brings 3D sound to livestreams

Sounds interesting! Will there soon also be a 3D hearing aid? 😊👂

"Popstar Hikaru Utada performs Jan. 19 at an online event that Sony bills as the world's first livestreaming to use full object-based spatial sound technology in real time. ..."

Turn the beat around: Sony brings 3D sound to livestreams - Nikkei Asia J-pop star's concert showcases new tech for smartphones and cars

MIT: How OpenAI used low-paid Kenyan workers to make ChatGPT less toxic. Really!

The Massachusetts Institute of Technology wags a moral finger again! 

I freely speculate here, but quite possibly this kind of work could not be done anymore in many Western countries, because of high labor costs & legislation, and ideological obsessions!

Were these workers really low paid compared to similar jobs offered in Kenya? Were these workers even better paid than other Kenyan workers in other jobs?

Otherwise, ChatGPT would not have been available yet!

"... OpenAI used a Kenyan company called Sama to train its popular AI system, ChatGPT, to generate safer content. Low-paid workers sifted through endless amounts of graphic and violent content on topics such as child sexual abuse, bestiality, murder, suicide, torture, self-harm, and incest. This story is a good reminder of all the deeply unpleasant work humans have to do behind the scenes to make AI systems safe [for Western and other consumers]. ..."

The economy is down, but AI is hot. Where do we go from here?

New research uncovers method to prevent mitochondrial DNA breakdown in the brain during aging - study

Here is another study on the subject of aging! One more piece of the puzzle! 😊

"... uncovered what seems to be a key preventive measure of the breakdown of DNA, which many believe causes aging and neurodegenerative diseases. ...
Focused on a protein called SIRT6, she has discovered that it seems to have remarkable properties. Its absence seems to downgrade DNA repair significantly. ... found that SIRT6 is a key regulator of mitochondrial function in the brain ...
Using transcriptomics (the study of the transcriptome, the complete set of RNA in a given cell population), metabolomics (the large-scale study of small molecules known as metabolites within cells, biofluids, tissues or organisms) and molecular assays (detecting the nucleic acid of the targeted pathogen), she and her team observed that in the absence of SIRT6 in the brain, nuclear-expressed mitochondrial genes are down-regulated (suppressing a response to a stimulus). 
In addition, the number of mitochondria per cell decays; there is an increase in the production of derivatives of molecular oxygen (reactive oxygen species or ROS) and the mitochondrial membrane potential is impaired, causing major metabolic changes. 
This effect is partially the result of SIRT6 regulating the expression of the mitochondrial Sirtuins 3 and 4. Reintroducing SIRT3 and 4 can rescue the membrane potential capacity. ..."

From the abstract:
"The SIRT6 deacetylase has been implicated in DNA repair, telomere maintenance, glucose and lipid metabolism and, importantly, it has critical roles in the brain ranging from its development to neurodegeneration. Here, we combined transcriptomics and metabolomics approaches to characterize the functions of SIRT6 in mouse brains. Our analysis reveals that SIRT6 is a central regulator of mitochondrial activity in the brain. SIRT6 deficiency in the brain leads to mitochondrial deficiency with a global downregulation of mitochondria-related genes and pronounced changes in metabolite content. We suggest that SIRT6 affects mitochondrial functions through its interaction with the transcription factor YY1 that, together, regulate mitochondrial gene expression. Moreover, SIRT6 target genes include SIRT3 and SIRT4, which are significantly downregulated in SIRT6-deficient brains. Our results demonstrate that the lack of SIRT6 leads to decreased mitochondrial gene expression and metabolomic changes of TCA cycle byproducts, including increased ROS production, reduced mitochondrial number, and impaired membrane potential that can be partially rescued by restoring SIRT3 and SIRT4 levels. Importantly, the changes we observed in SIRT6-deficient brains are also occurring in aging human brains and particularly in patients with Alzheimer’s, Parkinson’s, Huntington’s, and Amyotrophic lateral sclerosis disease. Overall, our results suggest that the reduced levels of SIRT6 in the aging brain and neurodegeneration initiate mitochondrial dysfunction by altering gene expression, ROS production, and mitochondrial decay."

New research uncovers method to prevent DNA breakdown, aging - study - The Jerusalem Post


Fig. 1: SIRT6 regulates gene expression levels


Latest Estimates of Ukrainian and Russian Casualties

Some numbers are harder to come by than others! Both sides in this war have not been very forthcoming.

"... The latest estimate comes from Norway's Chief of Defense Eirik Kristoffersen, who on Sunday said: “Russian losses are beginning to approach around 180,000 dead or wounded soldiers.
"Ukrainian losses are probably over 100,000 dead or wounded.
“In addition, Ukraine has about 30,000 civilians who have died in this terrible war." ..."

EXPLAINED: Latest Estimates of Ukrainian and Russian Casualties | Article | KyivPost Norway's Chief of Defense claims Russian losses are approximately double that of Ukraine

Calvin Coolidge - Less is More

The Roaring Twenties with President Coolidge! He lowered taxes! During his presidency, there were federal budget surpluses and the federal debt shrunk!
He did not run for a second term! He killed fifty laws!

Calvin Coolidge – A Life Leading by Example

Recommendable!

“... After all, the chief business of the American people is business. They are profoundly concerned with producing, buying, selling, investing and prospering in the world. I am strongly of opinion that the great majority of people will always find these are moving impulses of our life. ...”

The Press Under a Free Government (1925)

Address before the American Society of Newspaper Editors in Washington (17 January 1925)


Sunday, January 22, 2023

RARE: Kool & The Gang - Who's Gonna Take The Weight (1972)

Enjoy! This is the old style Kool & The Gang before the Disco age! Not much singing, mostly instrumental and jazz like!

South Dakota Governor Kristi Noem: 'Our Constitutional Freedoms Are Under Assault From Washingon'

She is one heck of a governor! Tax surplus to be refunded to tax payers and so on ...

Dauerfrostböden sind wohl doch keine Methan-Zeitbombe - Klimaschau

Wie meistens, wieder mal sehr empfehlenswert!

Scientists use WiFi routers to detect multiple human bodies and their movements through and behind walls

Amazing stuff! Privacy?

"... The team used DensePose, a system for mapping all of the pixels on the surface of a human body in a photo, developed by researchers at Facebook’s AI lab and a London-based team. What makes DensePose really powerful is its ability to identify over two dozen key points and areas in the human body, such as joints and body parts like the arms, head, and torso, allowing the AI to describe a person’s pose. Combining this with a deep neural network, they were able to map WiFi signals’ phase and amplitude sent and received by routers to coordinates on human bodies. ...
For their demonstration, the researchers used three $30 WiFi routers and three aligned receivers which bounce WiFI signals around the walls of a room. The system cancels out static objects and focuses on the signals reflected off moving objects, reconstructing the pose of a person in a radar-like image even if there’s a wall between the routers and the subjects. This approach could enable standard WiFi routers to see through a variety of opaque obstacles, including drywall, wooden fences, and even concrete walls. ...
This is not the first time researchers have attempted to “see” people through walls. In 2013, a team at MIT found a way to use cell phone signals for this purpose, and in 2018, another MIT team used WiFi to detect people in another room and translate their movements to stick figures. However, the new study from the Carnegie Mellon team delivers much higher spatial resolution. You can actually see what people who are moving are doing by looking at their poses. ..."

From the abstract:
"Advances in computer vision and machine learning techniques have led to significant development in 2D and 3D human pose estimation from RGB cameras, LiDAR, and radars. However, human pose estimation from images is adversely affected by occlusion and lighting, which are common in many scenarios of interest. Radar and LiDAR technologies, on the other hand, need specialized hardware that is expensive and power-intensive. Furthermore, placing these sensors in non-public areas raises significant privacy concerns. To address these limitations, recent research has explored the use of WiFi antennas (1D sensors) for body segmentation and key-point body detection. This paper further expands on the use of the WiFi signal in combination with deep learning architectures, commonly used in computer vision, to estimate dense human pose correspondence. We developed a deep neural network that maps the phase and amplitude of WiFi signals to UV coordinates within 24 human regions. The results of the study reveal that our model can estimate the dense pose of multiple subjects, with comparable performance to image-based approaches, by utilizing WiFi signals as the only input. This paves the way for low-cost, broadly accessible, and privacy-preserving algorithms for human sensing."

Scientists turn WiFi routers into 'cameras' that can see people through walls With the help of AI, the researchers were able to detect the movement of human bodies in a room using Wi-Fi routers -- even through walls.

DensePose From WiFi (open access)



Newly discovered Specialized Sperm Ribosomes Are Key to Male Fertility in Mice

Amazing stuff! It confirms that specialized ribosomes exist and that they are essential. There is some potential for future male contraceptives or to explain some forms of male infertility.

"A newly discovered type of ribosome, which synthesizes and then neatly and securely folds the proteins in sperm to prepare them for their arduous journey, seems to play a key role in male reproductive health ...
the ribosome packages proteins in a special way that enables them to last long enough to achieve fertilization. ...
that RibosomeST possesses a structurally distinct exit tunnel through which newly formed polypeptide chains pass and begin to fold into their final shape. ...
Further experiments on mouse cell lines showed that RibosomeST is the only ribosome capable of properly folding proteins essential to spermatogenesis ...
It provides a serious piece of heft to the hypothesis that specialized ribosomes not only exist but have important functional consequences in cellular processes. ..."

From the abstract:
"Ribosomes are highly sophisticated translation machines that have been demonstrated to be heterogeneous in the regulation of protein synthesis. Male germ cell development involves complex translational regulation during sperm formation. However, it remains unclear whether translation during sperm formation is performed by a specific ribosome. Here we report a ribosome with a specialized nascent polypeptide exit tunnel, RibosomeST, that is assembled with the male germ-cell-specific protein RPL39L, the paralogue of core ribosome (RibosomeCore) protein RPL39. Deletion of RibosomeST in mice causes defective sperm formation, resulting in substantially reduced fertility. Our comparison of single-particle cryo-electron microscopy structures of ribosomes from mouse kidneys and testes indicates that RibosomeST features a ribosomal polypeptide exit tunnel of distinct size and charge states compared with RibosomeCore. RibosomeST predominantly cotranslationally regulates the folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm. Moreover, we found that specialized functions of RibosomeST were not replaceable by RibosomeCore. Taken together, identification of this sperm-specific ribosome should greatly expand our understanding of ribosome function and tissue-specific regulation of protein expression pattern in mammals."

Specialized Sperm Ribosomes Are Key to Male Fertility in Mice | The Scientist Magazine® A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.

A male germ-cell-specific ribosome controls male fertility (no public access, but the article above contains a link to the PDF file)



How Do Rocky Planets like super earths Really Form in our Milky Way galaxy

Recommendable!

"A new theory for how rocky planets form could explain the origin of so-called "super-Earths"—a class of exoplanets a few times more massive than the Earth that are the most abundant type of planet in the galaxy.
Further, it could explain why super-Earths within a single planetary system often wind up looking strangely similar in size, as though each system were only capable of producing a single kind of planet. ...
In our solar system, there are two distinct types of planets: the smaller rocky inner planets closest to the sun and the outer larger water- and hydrogen-rich gas giants that are farther from the sun. In an earlier study ... this dichotomy led ... to suggest that planet formation in our solar system occurred in two distinct rings in the protoplanetary disk: an inner one where the small rocky planets formed and an outer one for the more massive icy planets (two of which—Jupiter and Saturn—later grew into gas giants). ..."

From the abstract:
"The formation of super-Earths, the most abundant planets in the Galaxy, remains elusive. These planets have masses that typically exceed that of the Earth by a factor of a few, appear to be predominantly rocky, although often surrounded by H/He atmospheres, and frequently occur in multiples. Moreover, planets that encircle the same star tend to have similar masses and radii, whereas those belonging to different systems exhibit remarkable overall diversity. Here we advance a theoretical picture for rocky planet formation that satisfies the aforementioned constraints: building upon recent work, which has demonstrated that planetesimals can form rapidly at discrete locations in the disk, we propose that super-Earths originate inside rings of silicate-rich planetesimals at approximately ~1 au. Within the context of this picture, we show that planets grow primarily through pairwise collisions among rocky planetesimals until they achieve terminal masses that are regulated by isolation and orbital migration. We quantify our model with numerical simulations and demonstrate that our synthetic planetary systems bear a close resemblance to compact, multi-resonant progenitors of the observed population of short-period extrasolar planets."

How Do Rocky Planets Really Form? | www.caltech.edu Scientists unveil a unified theory for rocky planet formation




Discovery of Silent Synapses May explain and Provide brain Plasticity in Adulthood

Amazing stuff! This could be a huge discovery!

"... Silent synapses are otherwise complete neuronal connections that lack a key signaling protein—AMPA receptors—that renders them inactive. They were thought to be unique to early development, as previous work found that the silent connections vanish by the time a mouse has reached adulthood. But researchers may have been looking in the wrong place. In young animals, silent synapses are formed from larger protrusions called dendritic spines. But in adults, they can be found on the ends of threadlike structures called filopodia, according to the new study. ..."

From the abstract:
"Newly generated excitatory synapses in the mammalian cortex lack sufficient AMPA-type glutamate receptors to mediate neurotransmission, resulting in functionally silent synapses that require activity-dependent plasticity to mature. Silent synapses are abundant in early development, during which they mediate circuit formation and refinement, but they are thought to be scarce in adulthood. However, adults retain a capacity for neural plasticity and flexible learning that suggests that the formation of new connections is still prevalent. Here we used super-resolution protein imaging to visualize synaptic proteins at 2,234 synapses from layer 5 pyramidal neurons in the primary visual cortex of adult mice. Unexpectedly, about 25% of these synapses lack AMPA receptors. These putative silent synapses were located at the tips of thin dendritic protrusions, known as filopodia, which were more abundant by an order of magnitude than previously believed (comprising about 30% of all dendritic protrusions). Physiological experiments revealed that filopodia do indeed lack AMPA-receptor-mediated transmission, but they exhibit NMDA-receptor-mediated synaptic transmission. We further showed that functionally silent synapses on filopodia can be unsilenced through Hebbian plasticity, recruiting new active connections into a neuron’s input matrix. These results challenge the model that functional connectivity is largely fixed in the adult cortex and demonstrate a new mechanism for flexible control of synaptic wiring that expands the learning capabilities of the mature brain."

Silent Synapses May Provide Plasticity in Adulthood | The Scientist Magazine® Inactive synapses—found on tiny neuronal projections called filopodia—are abundant in the adult brain, a mouse study suggests.

Filopodia are a structural substrate for silent synapses in adult neocortex (no public access, but article above contains link to PDF file)



How Ukraine is using drones to document Russian 'war crimes'

Let the international war crimes tribunal against Putin the Terrible and his accomplices begin immediately, preferably in Nuremberg, Germany! (in absentia or not).

How an smartphone app is helping low vision people navigate life better

Amazing stuff!

The Castrati: A dark corner in music history

Very recommendable! One of those strange episodes in the history of music! At the end listen to the recording of one of the last famous castrati.

Saturday, January 21, 2023

Are India & China heading towards a water war?

Satellite images show China is building a dam near Arunachal border. In response, India has also expedited hydro-power projects in the state. 


U.S. General Ben Hodges: “We need to decide that we want Ukraine to win”

Recommendable!

Mexico: Most dangerous country for journalists & 2022 has been deadliest with 113 killed journalists

Horrible!

Support building for Republican resolution in the U.S. Congress to authorize military force against Mexican drug cartels, eviscerate those behind the fentanyl crisis

They say desperate times call for desperate measures! However, this is a well known very slippery slope to use the military against criminals!

The "War on drugs" is one of those tragic, regrettable, well known human fallacies!

What if a soldier e.g. inadvertently shoots an innocent, bystanding child?

With a phony, compromised, pathological liar, phony, compromised, pathological liar, head of the Biden clan, senile and demented 46th President who refuses to secure the border from an invasion of immigrants, this is very questionable.

Do you trust the current Secretary of Defense or the Joint Chiefs of Staff to carry out this mission? You got to be kidding!

More straight forward would be to impeach the responsible members of the administration and the president himself! This would also put Dimocratic Party members of the U.S. Congress on notice!

I also totally do not understand why the governors of the two most affected border states Arizona and Texas have not taken bolder and stronger measures to secure the border themselves if the federal government so obviously has failed for two years!

"Republican congressmen introduced a resolution earlier this month to authorize American military action against the terroristic drug cartels that have overwhelmed Mexican government forces and trafficked the number one killer of adults 18-45 into the United States. That resolution is fast gaining support in the House. ..."

Support building for Republican resolution to authorize military force against Mexican drug cartels, eviscerate those behind the fentanyl crisis - TheBlaze

Unearned authorship pervades science so do other questionable research practices

Science is a human endeavor! Like all human endeavors it is flawed! 

Anybody, who claims science is beyond doubt is a fool and/or a charlatan! The history of science is littered with once great, widely accepted, but in hindsight grotesque theories that became obsolete!

"... The International Research Integrity Survey (IRIS) received responses from around 47,000 academics in Europe and the United States about their experience of eight QRPs, including inadequate peer review; deliberate failure to report contradictory findings; lack of supervision of junior colleagues; and conducting research without ethics approval. Inappropriate authorship — listing authors who did not adequately contribute to a manuscript — was the most common QRP encountered by the respondents. ...
The responses were collected from academics across a broad range of fields, including the natural sciences, social sciences and humanities. ..."

Unearned authorship pervades science

Auto-Abos: Steigendes Interesse am Netflix-Modell für Autos in Deutschland

Scheint eine interessante Idee zu sein! Für jemanden, der ein Auto nicht ständig braucht, wäre das vielleicht eine Alternative!

Auto-Abos: Steigendes Interesse am Netflix-Modell für Autos Viele Autofahrer wollen kein eigenes Fahrzeug mehr besitzen. Neben Angeboten wie Carsharing und Leasing werden sogenannte Auto-Abonnements beliebter. In diesem Jahr könnte erstmals die Schwelle von 100 000 neuen Abo-Abschlüssen geknackt werden.

Abolish DEI Bureaucracies and Restore Colorblind Equality in Public Universities

The return of a very prominent and influential race/skin color based ideology in the first quarter of the 21st century in Western countries only a little more than half a century after World War II ended is truly shocking!

In the U.S. this return is even more disturbing as racial segregation was only ended in the 1960s! Reminder: What was Martin Luther King Jr.'s dream!

"There is a lot that state legislatures can do to reverse the illiberal takeover of higher education through Diversity, Equity, Inclusion (DEI) offices that, ironically, stifle intellectual diversity, prevent equal opportunity, and exclude anyone who dissents from a rigid orthodoxy. Here are four proposals for reforming public universities:

1. Abolish DEI bureaucracies. 
2. End mandatory diversity training. 
3. Curtail political coercion. 
4. End identity-based preferences. ..."

Abolish DEI Bureaucracies and Restore Colorblind Equality in Public Universities | Manhattan Institute

The ‘breakthrough’ obesity drugs that have stunned researchers. Really!

Update of 5/7/2023: Meanwhile, I have read more about recent new and apparently effective obesity medications. I have also out of ignorance disregarded the benefits of such medications for obese people who suffer from diabetes. Here is my latest blog post about this subject.


Good news! However, would not behavioral, lifestyle, and dietary changes suffice in many cases of obesity? Some skepticism is in order!

I am not to sure, I find the results that impressive!

How much of a disease is obesity? 

"... They described the details of an investigation of a promising anti-obesity medication in teenagers, a group that is notoriously resistant to such treatment. The results astonished researchers: a weekly injection for almost 16 months, along with some lifestyle changes, reduced body weight by at least 20% in more than one-third of the participants. [Do you think this is an impressive outcome? Rather dubious!] Previous studies had shown that the drug, semaglutide, was just as impressive in adults. ...
This energy has pervaded the field of obesity medicine for the past few years. After decades of work, researchers are finally seeing signs of success: a new generation of anti-obesity medications that drastically diminish weight without the serious side effects that have plagued previous efforts. ...
These drugs are arriving in an era in which obesity is growing exponentially. Worldwide obesity has tripled since 1975; in 2016, about 40% of adults were considered overweight and 13% had obesity, according to the World Health Organization (WHO). With extra weight often comes heightened risk of health conditions such as type 2 diabetes, heart disease and certain cancers. The WHO recommends healthier diets and physical activity to reduce obesity, but medication might help when lifestyle changes aren’t enough. The new drugs mimic hormones known as incretins, which lower blood sugar and curb appetite. Some have already been approved for treating type 2 diabetes, and they are starting to win approval for inducing weight loss.
The ability to melt weight away by tweaking biology gives credence to the idea that obesity is a disease. [????]  ...
Research questions abound, including who will respond to treatment and whether people will have to take these drugs for life — a huge barrier to access, given that they also carry a hefty price tag: the injections often cost upwards of US$1,000 each month. ...
The seeds of today’s success were sown decades ago, when Jeffrey Friedman was racing to figure out which gene mutation was making the mice in his laboratory eat until they became obese. ... discovered that the faulty gene encoded leptin, a hormone that is produced by fat tissue and induces a feeling of fullness. Giving leptin supplements to mice that lacked it reduced their hunger and body weight.
“That really revolutionized our thinking about the biological basis of obesity and appetite regulation,” ...
Those receiving weekly injections of semaglutide lost, on average, 14.9% of their body weight after 16 months of treatment; those who received a placebo lost 2.4% on average.
Historically, it hasn’t been possible to safely decrease body weight by more than 10% through pharmacological methods ..."

The ‘breakthrough’ obesity drugs that have stunned researchers A class of drugs that quash hunger have shown striking results in trials and in practice. But can they help all people with obesity — and conquer weight stigma?



Two freedom minded institutes demand to abolish diversity, equity, and inclusion (DEI) at public universities and colleges

Good news! I would not hire with any academic institution that would require me to consent to DEI in any form or shape!

I am not sure whether prohibition of these activities is the right choice, but something has to be done about it especially also when taxpayers are paying for this indoctrination!

"It’s a full-frontal assault on academic freedom: all around the country, progressive activists are using a toxic web of publicly funded, politically radical diversity, equity, and inclusion (DEI) practices to take over higher education.

Look no further than Arizona’s public university system, where a new Goldwater Institute report uncovered that up to 80% of faculty job postings require applicants to pledge fealty at the altar of “wokeness” by providing mandatory “diversity statements.” As Goldwater Senior Fellow Jonathan Butcher explains, “DEI has become institutionalized on Arizona college campuses: you must consent to the prevailing ‘woke’ orthodoxy to be hired by a state university ...
But Goldwater has a plan to dismantle the ideological domination of DEI programming over public colleges. As detailed in a Wall Street Journal op-ed, Goldwater and the Manhattan Institute this week released a package of legislative reforms that would abolish DEI offices, prohibit mandatory diversity training and diversity statements, and end racial and other identity-based preferences in admissions and hiring. ..."

Week in Review: I Pledge Allegiance to…Progressivism?

Denmark to ditch public Christian holiday to meet Nato defense spending increase

They say that Scandinavian people are generally quite pragmatic and down to earth! Here is another proof! 😊

"Denmark wants to reach its Nato financial commitments three years ahead of schedule, and has introduced a parliamentary bill to boost state coffers — by ditching a centuries-old Christian public holiday.
The Danish government's proposal, a coalition between centre-left and centre-right parties, has found a way to bring forward the two percent of their GDP to defence spending agreed for 2030.
How? By removing a public holiday from the workers' calendar, which, according to its federal ministry of finance, will result in DKK 3.2bn (€430m) a year. ..."

Denmark to ditch Christian holiday to hit Nato spending

Charlie Chaplin - Adenoid Hynkel's Palace - The Great Dictator (1940)

Enjoy! The genius of Charlie Chaplin!

Friday, January 20, 2023

46th President continues to squander his last best chance to go down in history as a great president!

The last best chance for the 46th President to become a great president is to resign immediately for health reasons and set an example for future generations.

He could now even point to the recent surprise announcement by the Prime Minister of New Zealand!

Who is to blame? One person would be definitely the First Lady Dr. Jill Biden! She should have convinced her husband years ago that it was time to play with grand children, eat more ice cream, and to play golf! But vanity won!

Of course, then we would have to deal with the first black female Vice President Mistress Kamala to become the next president. Oh well! We will survive that too for two more years!


(In part) Hydrogen-powered 19-seat plane takes off in test flight in the UK

How much water vapor in the atmosphere is harmless? The emphasis here is on "in part" hydrogen powered.

"In a record trip for low-carbon aviation, a startup has completed a test flight [on 1/19/2023] of a 19-seat aircraft powered in part by hydrogen fuel cells. It’s the largest plane that ZeroAvia, a leader in developing hydrogen-electric systems for planes, has tested in the air to date. 
The flight took off from Cotswold Airport in the UK and lasted about 10 minutes altogether. During the flight, the plane’s left engines were powered by a combination of hydrogen fuel cells and batteries, while the right side relied on the fossil fuel kerosene. 
Aviation accounts for about 3% of global greenhouse gas emissions [only 3%????], and the industry is growing quickly. ..."

Hydrogen-powered planes take off with startup's test flight | MIT Technology Review

The Federal Aviation Administration will be looking at rules that have curbed drone deliveries

Good news!

"... Federal rules governing the use of drone aircraft are holding back companies interested in making deliveries that way, panelists said at the recent CES 2023 in Las Vegas. But help might be on the way this year in the form of revised regulations, says FAA official Abigail Smith ..."

Why drone delivery hasn’t taken flight in the US | Smart Cities Dive

Some Utah lawmakers claim overgrown forests suck too much water to save lakes like Lake Powell

That is an interesting concern! It is well known that overgrown or badly managed forests can be prone to wildfires.

"... Claiming “overgrown” forests are guzzling Utah’s water resources dry, rural members are now calling for a major logging initiative as the best hope for saving the shrinking Great Salt Lake and Lake Powell, despite a lack of scientific evidence that tree removal would make a big difference. ...
Utah’s 5 million acres of forests are crowded with 100 to 200 trees per acre, about 10 times the densities in the 1800s, Randy Julander, a retired federal hydrologist, told the caucus gathering. And the trees on about a quarter of this land are standing dead because there isn’t enough water in the ground to sustain them, he added. ..."

Utah lawmakers pitch tree removal as plan to save Great Salt Lake “Yellow Cake” legislators claim logging can save Great Salt Lake, but scientists are doubtful.

Johns Hopkins University Workshop aids understanding of structural racism. Really!

When an elite university offers a workshop promoting brainwashing and indoctrination! So appalling!

"The Structural Racism Convening, hosted last week by the Johns Hopkins School of Nursing, brought together 40 top scholars from the Johns Hopkins Structural Racial Discrimination and Resilience Collaborative, or SRDRC, Johns Hopkins AI-X Foundry, and the SNF Agora Institute to explore how data science, machine learning, and concepts from complex adaptive systems can help humans understand the various ways structural racism affects people and health outcomes. ...
"We need a more refined understanding of exactly how this fabric of discriminatory practices, or racial discrimination, affects health outcomes," said Szanton [dean of the School of Nursing]. ..."

Workshop aids understanding of structural racism | Hub A workshop hosted by the Johns Hopkins School of Nursing explores how data science and machine learning can help our understanding of the effects of structural racism on health outcomes

There’s a long history of solar-powered landers and rovers on Mars running out of power

Food for though! Is that not curious? What is true on Mars may also be applicable on earth?

"... “It wouldn’t be surprising for the rover to fail to come out of hibernation because it is solar-powered, and there’s a long history of solar-powered landers and rovers on Mars running out of power,” says David Flannery, an astrobiologist at Queensland University of Technology in Brisbane, Australia. ..."

What’s happened to China’s first Mars rover? Zhurong was supposed to wake from its [winter] slumber last month, but there have been no reports on its status.

Ukraine's President Zelensky Says He is Not entirely Sure if Vladimir Putin is Still Alive

Perhaps, Zelensky has a point! Obviously, Putin the Terrible has visibly aged significantly in recent years! Perhaps, he is not really in charge anymore and has become more or less like a front man!

Zelensky Says He is Not Sure if Vladimir Putin is Still Alive | Article | KyivPost Ukraine’s President questioned whether there is anyone reliable in the Kremlin with whom he could actually negotiate.


Animal Food Of The Future: High-protein Black Soldier Flies

Sounds delicious! Good to know what a pig, cattle, or chicken was fed with before you eat it!

"Flies are the food of the future. Maybe not for humans, but certainly for animals. Flies eat absolutely anything, breed like crazy, they’re extremely high in protein, and they’re much more sustainable as a foodstuff than anything that grows in the ground. ...
FreezeM says it’s addressing a desperate need for sustainable alternatives to soy and fishmeal, the most widely-used proteins for animal feed.
The company takes its name, FreezeM, from its early involvement in freezing BSF eggs (rather than larvae). Now it is also able to pause their development, at room temperature, after they hatch into larvae. ..."

Food Of The Future: Nature's Ultimate Recycling Machine Startup breeding billions of high-protein Black Soldier Flies for livestock

Black Soldier Fly larvae, or maggots.


Thailand and Indonesia gear up for return of millions of Chinese tourists

More than 20-30 years ago it was almost unthinkable that citizens from a communist country would travel the world and non communist tourist destination countries were eager to do business with them!

It appears Chinese tourism has become a serious economic factor for some of the destination countries.

"China's reopening raises hopes for the return of Chinese visitors, who accounted for nearly a third of Thailand's 40 million foreign tourist arrivals in pre-pandemic 2019.
The government expects at least five million Chinese tourists this year, with some 300,000 in the first quarter." (Reuters)

Thailand and Indonesia gear up for return of Chinese tourists - Nikkei Asia After a three-year lull, is Southeast Asia's travel sector ready for a rush?