Friday, April 18, 2025

We’re on the verge of a new universal Spring allergy treatment using the monoclonal antibody Omalizumab

Good news! A recommendable survey article!

"... Omalizumab, sold as Xolair, is an asthma medication that was approved more than 20 years ago, but it has proven successful in treating seasonal allergies in recent preliminary trials. So successful, in fact, that now some doctors in the US are prescribing it for certain patients during hay fever season. It is an injection, rather than a pill or a spray, that’s given a couple of weeks before pollen and grass levels start to rise.

One obvious benefit is you get a single shot and enjoy your spring. But even better, omalizumab can forestall allergic reactions at the source. That means an injection could stop all allergic reactions — not only seasonal allergies but food allergies (such as peanuts) and insect allergies for a prolonged period of time. This class of treatment — monoclonal antibodies, special artificial proteins that carry instructions to the body’s immune system — have the potential to be a genuine all-in-one allergy wonder drug. ...

Large clinical trials are underway in China and Japan, which could lead to omalizumab’s approval in those countries for seasonal allergies. The next generation of monoclonal antibody allergy treatments is already in the works. ...

Monoclonal antibodies stop that process before it begins. They deliver artificial proteins that carry instructions to your immune system to block the receptors that create allergic reactions and prevent the overresponse that releases histamine in the first place. ..."

Credits: Global Health NOW: Pandemic Agreement Reached; A Brain Bank Hangs in the Balance; and Spore-Driven Threats

We’re on the verge of a universal allergy cure "The one allergy treatment to rule them all, explained."

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