Wednesday, January 22, 2025

Gene edited Insulin-producing beta cells avoid immune attack in treatment of type 1 diabetes over extended period

Good news!

"Gene-edited insulin-producing beta cells have survived for a month after being injected into a man with type 1 diabetes. These tweaked cells have a protein called CD47 on their surface, which tells the immune system not to destroy them. Only a small number of cells were injected into the man’s arm, but they have produced insulin and avoided his immune system’s crosshairs so far, suggesting that they could become an effective treatment for diabetes."

Nature Briefing: Translational Research

Gene-edited cells that evade rejection show promise in type 1 diabetes "Insulin-producing cells injected into a man with type 1 diabetes have survived for a month so far without the need for immune suppression"

No comments: