Good news! Are we finally getting away from opioids as a severe painkiller?
Again, the excessive precautionary principle prevents unnecessarily the speedy approval of new drugs! Maybe President Trump should do something about it as well!
"The first new class of pain medication to market in decades could be approved by the US Food and Drug Administration by the end of [January]. Suzetrigine, from Vertex Pharmaceuticals, stops pain by blocking certain receptors in the peripheral nervous system rather than acting in the brain. Clinical trials showed that it works, but they were too short to rule out side effects from long-term use. A success for suzetrigine could renew funding interest in the development of new, non-opioid painkillers, a notoriously challenging field that has struggled to make headway in recent years."
"The FDA is weighing the regulatory fate of Vertex’s small-molecule suzetrigine, an inhibitor of voltage-gated sodium channel 1.8 (NaV1.8), for moderate to severe acute pain. A decision is due by 30 January. If approved, the oral drug will be the first new class of pain medication to market in decades ...
Success for Vertex could also bolster interest in related pain-associated NaVs. These ion channels have a key role in pain, helping to conduct electrical signals known as action potentials in peripheral pain-sensing nerves, also known as nociceptors. ...
“This is the first medicine that is specifically designed to only affect pain,” ..."
NaV1.8 inhibitor poised to provide opioid-free pain relief "Vertex’s first-in-class suzetrigine could soon usher in a new class of analgesic."
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