Good news! Sounds too good to be true? Perhaps, exaggerated, but not wrong. Cancer is history (soon)!
According to the company's website: "We target the p53 based tumor suppression mechanism that is mutated in over 60% of cancers, including glioblastoma, colon, bladder, ovarian, and small cell lung cancers."
"An Israeli startup has created a new protein-based cancer treatment that it says has no discernable side effects and the potential to replace far more costly and physically damaging forms of therapy, such as chemotherapy.
ExoProTher says its therapy solely targets the mutated cells that allow tumors to spread throughout the body, and, unlike other treatments, allows healthy cells to survive.
Now being tested in the preclinical stage, the drug uses the p53 protein, which suppresses tumors. The p53 molecules bind themselves to damaged DNA and tell irreparable DNA to go into apoptosis (cell death). This prevents cells with damaged DNA from grouping together and forming tumors.
Israeli scientists Lana Volokh and Alex Tendler co-founded the startup (whose name derives from EXOsome PROtein THERapy) in 2017, to develop a drug using protein from chicken cells. ...
P53 was first discovered in 1979 when scientists noticed the protein sticking to infected cells and signaling antibodies to fight infection. In 1989, the gene that produces the protein was determined to be a tumor suppressant.
And while there has been no successful American or European way so far to use p53 to treat cancer, Tendler tells NoCamels that ExoProTher has become the first company to successfully develop a therapy using the protein – by turning to a non-human source.
The company says nobody has previously considered using chicken cells or indeed any non-human cells.
“Chicken cells [are] proven to have similar functions to human cells but not to the point where the mutated cells can prevent them from working,” Tendler explains. ..."
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