Wednesday, April 27, 2022

Making blood donations a thing of the past

Good news! I think it is quite possible that humanity will not dependent anymore on blood donations in the very near future.

"... Israeli startup RedC Biotech has a radical solution: generating an unlimited supply of universal red blood cells from a single donation of human stem cells. ...
The need is great: While around 120 million blood donations are given every year worldwide, the World Health Organization (WHO) estimates that there’s a shortage of up to 100 million units, mostly in low-income countries and regions. ...
Donated blood is also expensive. The average US hospital pays about $200 per blood transfusion, and that does not include staffing and infrastructure expenses involved in transfusions. ...
WHO data reveals that up to two million people die every year as a result of blood loss from violence or injury; some 200,000 women die in childbirth from blood loss; and 300,000 babies are born every year with blood disorders requiring transfusions ...
RedC’s process would start with a stem cell donation from a single “universal donor” who has a special variant of the blood type O negative suitable for most people.
Since stem cells can multiply continuously and differentiate into any kind of cell, they can be reprogrammed to create a master cell bank.
Samples from the master cell bank are used to grow batches of universal red blood cells in a bioreactor for about a month. The harvested and cleaned mature cells would be shipped to hospitals ..."

From the company's website:
"Innovative 3D stem cell cultivation in chemically defined serum-free media
Multi-patent protected, exclusively licensed core technology ...
Red blood cell production will move from lab scale to large scale bioreactors
Uniform, undifferentiated, self-renewable, efficiently cultured human stem cells cultivated as single-cells in suspension
At an extremely high cell concentration the cells are differentiated to become Red Blood Cells
Red Blood Cells are harvested, rinsed, concentrated, packed and distributed ..."

The startup aiming to make blood donations a thing of the past - ISRAEL21c If RedC Biotech is successful, hospitals will no longer depend on blood donations but will be able to buy blood on demand as a pharmaceutical product.



No comments: