Recommendable! Brief overview about some of the latest research on senescent cells!
"... that signals from dysfunctional mitochondria to the nucleus result in bits of chromatin — a complex of proteins, DNA and RNA in the nucleus — fragmenting into pieces and pushing into the cell’s cytoplasm. ... that detection by the cell of random the chromatin fragment triggers the inflammatory senescence-associated secretory phenotype. ...
... that obesity increases senescence and diminishes the function of fat-tissue derived mesenchymal stem cells in comparison to the same type of cells from non-obese controls. ...
... senescent cells contribute to chemotherapy-induced bone loss. ..."
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