Good news! Will genetically modified humans become reality soon? Please remove the sneezing gene!
"Trained on a dataset that includes all known living species – and a few extinct ones – Evo 2 can predict the form and function of proteins in the DNA of all domains of life and run experiments in a fraction of the time it would take a traditional lab. ..."
"... With Evo 2, you can enter a sequence of up to 1 million nucleotides. The million-nucleotide window in biology is important, as it allows us to explore long-distance interactions between two or more genes that may not be physically close to one another on the DNA molecule. ...
Evo 2, on the other hand, also includes the known genomes of 15,000 or so plants and animals – the eukaryotes – which includes humans. Our dataset has now expanded from about 300 billion nucleotides to almost 9 trillion with Evo 2. In terms of safety, we have left out the genomes of viruses to prevent Evo 2 from being used to create new or more dangerous diseases. It’s like a representative snapshot of all species on Earth. ...
In the real world, these mutations happen by chance. With Evo 2, we can be more direct and steer toward mutations that have useful functions. Evo 2 also includes machine learning models that will tell you if the sequence exists in nature and predict how this new sequence will function in real life. ...
The model is actually very good at distinguishing which mutations are just random, harmless variations and which cause disease. ..."
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