Synthetic biology breakthrough fixes CO2 from the air better than nature by two orders of magnitude by using modified bacteria

Human ingenuity can easily handle the recycling of CO2 from the atmosphere at any volume if needed! Thus, this is one more reason why Global Warming is a hoax and Climate Change is a religion! Don't believe the propaganda and demagoguery!

"Scientists at the Max Planck Institute have developed a synthetic pathway that can capture CO2 from the air more efficiently than in nature, and shown how to implement it into living bacteria. The technique could help make biofuels and other products in a sustainable way. ..."

"Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers ... have developed a synthetic biochemical cycle that directly converts CO2 into the central building block Acetyl-CoA. The researchers were able to implement each of the three cycle modules in the bacterium E.coli, which represents a major step towards realizing synthetic CO2 fixing pathways within the context of living cells."

From the abstract:

"Synthetic biology offers the opportunity to build solutions for improved capture and conversion of carbon dioxide (CO2) that outcompete those evolved by nature. Here we demonstrate the design and construction of a new-to-nature CO2-fixation pathway, the reductive tricarboxylic acid branch/4-hydroxybutyryl-CoA/ethylmalonyl-CoA/acetyl-CoA (THETA) cycle. The THETA cycle encompasses 17 enzymes from 9 organisms and revolves around two of the most efficient CO2-fixing enzymes described in nature, crotonyl-CoA carboxylase/reductase and phosphoenolpyruvate carboxylase. Here using rational and machine learning-guided optimization approaches, we improved the yield of the cycle by two orders of magnitude and demonstrated the formation of different biochemical building blocks directly from CO2. Furthermore, we separated the THETA cycle into three modules that we successfully implemented in vivo by exploiting the natural plasticity of Escherichia coli metabolism. Growth-based selection and/or 13C-labelling confirmed the activity of three different modules, demonstrating the first step towards realizing highly orthogonal and complex CO2-fixation pathways in the background of living cells."

Synthetic biology breakthrough fixes CO2 from the air better than nature

First step towards synthetic CO2 fixation in living cells Three modules forming a new-to-nature CO2 fixation cycle successfully implemented in E.coli

Construction and modular implementation of the THETA cycle for synthetic CO2 fixation (open access)

Fig. 1: The THETA cycle and its realization