Contains some nice charts! Cancer is history (soon)!
"Engineering innate immune cells, like natural killer (NK) cells, NK T cells, γδ T cells and macrophages for use in immunotherapy could help to overcome the functional limitations – such as poor efficacy in solid tumours – and high costs of CAR T cells. Macrophages ... are highly plastic cells that are critical to maintaining homeostasis by phagocytosis and tissue repair.
Recent studies into the use of CAR macrophages for cancer treatment showed no serious side effects, but only transient disease stabilisation, in four out of eight patients."
The landscape of CAR-engineered innate immune cells for cancer immunotherapy (no public access, a review article, but article above contains link to PDF)
No comments:
Post a Comment