A glimpse of the next generation of AlphaFold

Good news! A very remarkable success story continues! Bravo! Delving into the secrets of life!

"... It unlocks new understanding and significantly improves accuracy in multiple key biomolecule classes, including ligands (small molecules), proteins, nucleic acids (DNA and RNA), and those containing post-translational modifications (PTMs). ...

In 2022, AlphaFold’s structure predictions for nearly all cataloged proteins known to science were made freely available via the AlphaFold Protein Structure Database, in partnership with EMBL's European Bioinformatics Institute (EMBL-EBI).

To date, 1.4 million users in over 190 countries have accessed the AlphaFold database, and scientists around the world have used AlphaFold’s predictions to help advance research on everything from accelerating new malaria vaccines and advancing cancer drug discovery to developing plastic-eating enzymes for tackling pollution. ..."

A glimpse of the next generation of AlphaFold - Google DeepMind Progress update: Our latest AlphaFold model shows significantly improved accuracy and expands coverage beyond proteins to other biological molecules, including ligands.

Predicted structure of CasLambda (Cas12l) bound to crRNA and DNA, part of the CRISPR subsystem.