Tuesday, December 21, 2021

A new journal: Transactions on Machine Learning Research

Exciting good news! The first editors and founders of this new journal will be the well known and highly cited researchers Hugo LarochelleRaia Hadsell, and Kyunghyun Cho.

I am looking forward to the first edition!

Motivation for another journal: "The field of machine learning has grown exponentially over the last decade, and we [the three editors/founders] have observed firsthand the pains that come with such growth. Some of these pains are practical, manifested in the crashing review platforms or overcrowded poster halls. But others strike deeper, revealing themselves through disenchantment with the exclusivity of our top conferences, or criticisms that conferences don’t seem to be sufficiently successful at highlighting the most impactful work, have slow turnaround from submission to decision, create high-stakes pressure and stress around a handful of fixed deadlines, and are perceived to be diminishing in the quality of the peer review process."

Aims of the new journal: "This journal is a sister journal of the existing, well-known Journal of Machine Learning Research (JMLR), along with the Proceedings of Machine Learning Research (PMLR) and JMLR Machine Learning Open Source Software (MLOSS). However it departs from JMLR in a few key ways, which we hope will complement our community’s publication needs. Notably, TMLR’s review process will be hosted by OpenReview, and therefore will be open and transparent to the community. Another differentiation from JMLR will be the use of double blind reviewing, the consequence being that the submission of previously published research, even with extension, will not be allowed. Finally, we intend to work hard on establishing a fast-turnaround review process, focusing in particular on shorter-form submissions that are common at machine learning conferences. ...
Certifications This will be a unique feature of TMLR, which is aimed at separating editorial statements on submitted work from their claim-based scientific assessment. An accepted paper will have the opportunity of being tagged with certifications, which are distinctions meant to highlight submissions with additional merit."


Journal of Machine Learning Research/TMLR

Special Prosecutor Releases Full Report on Investigation of Soros-Backed Prosecutor in Jussie Smollett Case

I guess, I missed those troubling aspects of this case before. Admittedly, I was not following this Smollett case very close anyway!

As a side note, the article below and my brief Google search for the special prosecutor's final report came up only with a PDF file that was poorly done. In both sources, the document was scanned as an image,so one can not easily copy and past text passages of interest! This is lousy!

However, this is schocking how blind justice was turned into racially motivated justice! When prosecutors follow political instructions, justice is denied!

"There was suspicion of political interference, after Tina Tchen, a former aide to First Lady Michelle Obama, reached out to the prosecution on behalf of the Smollett family. Judge Michael Toomin ordered a special prosecutor to intervene, both to take up the Smollett case and to investigate Foxx and her subordinates at the Cook County State Attorney’s Office.
Last year, a 12-page summary of the summary was released, in which Webb revealed that while there were abuses of discretion and possible ethical breaches by Foxx and her office, especially in misleading the public about key facts like Smollett’s past criminal record, there had been no criminal violations and Tchen’s intervention had not been decisive.

The full 60-page summary provides the evidentiary basis for the shorter 12-page version. It includes details of interviews with Foxx and Tchen, as well as others involved, and refers to text messages and other bases for the report’s conclusions. ...
Some of the additional details include confirmation of earlier reports that Foxx’s office declined to notify Chicago Police Department Superintendent Eddie Johnson that it was dropping charges against Smollett. Johnson had been vocal in public about his disgust with Smollett’s evident attempt to fake a hate crime, wasting resources and diminishing real racism.

The full report also provides further detail about Foxx’s false statements that Smollett had no prior criminal record — when, as the 12-page report said, “a prior misdemeanor conviction out of California from September 22, 2007 for DUI, driving without a license, and giving false information to the police, for which he was placed on 24 months of probation.” The full 60-page report adds that false statements about Smollett’s record were “particularly troubling” because his prior conviction “related, in part, to making a false statement to police,” and was therefore similar to the present case in Chicago. ..."

Special Prosecutor Releases Full Report on Investigation of Soros-Backed Prosecutor in Jussie Smollett Case The office of Special Prosecutor Dan Webb released its full 60-page “summary report” Monday afternoon of its investigation into the office of Cook County State’s Attorney Kim Foxx over her improper handling of the Jussie Smollett case in 2019.

Renewing the relationship: Putin’s visit to India

Recommendable!

"The end of 2021 may prove to be an important milestone in the evolution of strategic relations between Russia and India. On 6 December, Russian President Vladimir Putin flew into New Delhi on a one-day state visit. The one-on-one meeting with Indian Prime Minister Narendra Modi, which lasted three and a half hours, was aimed at restoring confidence between the two powers as time-proven and trusted strategic partners.

For Putin, the trip to India was only his second overseas visit since the outbreak of the Covid-19 pandemic (the other was the first meeting with his US counterpart Joe Biden in Geneva). That fact alone signifies the importance of India to the Kremlin and the desire to keep relations close. But Putin’s brief visit to New Delhi was just part of broader high-level bilateral talks, which included an impressive entourage representing both countries. ...
They also signed another 10-year agreement on joint military–technical cooperation until 2031 and agreed to expand and deepen bilateral defence cooperation. Adding to that, Russia has reaffirmed its position as one of the principal providers of advanced military technology to the Indian military. Since 1991, India has acquired a comprehensive suite of weapons and platforms for all its fighting services worth some US$70 billion. The current value of India’s defence contracts with Russia is approximately US$15 billion.

The target of US$30 billion in annual trade by 2025, which was set in 2019, was confirmed. ..."

Renewing the relationship: Putin’s visit to India | The Strategist

The 1970s Cooling Scare or Another Ice Age Was Real

Recommendable! In the 1970s, the global cooling hoax was the propaganda and demagoguery of the day. I remember it well.

Inside the South African Lab With the First Omicron Findings

Don't buy into the new hysteria and panic about the latest variant!
Yes, it is more infectious and perhaps more transmissible, but it is also relative harmless like the variants that came before!

Why SARS-CoV-2/Covid-19 is a relatively harmless disease and why the cure was worse than the disease.


It is long high time to return to normal life like before the Covid-19 pandemic!



Dirty Harry IV - Too much sugar is bad for you

Does anyone believe you can still make such movies in our time! You are fooling yourself!

Monday, December 20, 2021

The murder of ancient Alexandria's great scholar Hypatia

Very recommendable! She was murdered in the streets of this famous city by religious fanatics!

Texas unveils first stretch of border wall funded by the state

Bravo Texas! Other border states ought to follow this example!

Charlamagne Tha God asks Kamala Harris ‘who the real president’ is

Incredible! VP Harris appears more demented than the 46th President. And she has or worse she needs a minder, who interrupted the interview to give Ms. Harris time to prepare an answer!
This is better than any episode of Saturday Night Life or any other comedy show!
The world is laughing!

Donald Trump's attorney on his lawsuit against New York AG Letitia James

Bravo President Trump! Go after this phony, fraudulent, and partisan prosecutor!
Her JD from Harvard University should be rescinded!
She should be debarred by the American Bar Association ASAP!

Christie’s Sells $7.1 Billion in Art, the Highest in Five Years

Hedging against inflation by driving up prices of art pieces!

"All three of the world’s chief auction houses have recently reported strong sales, citing, among other factors, millennial collectors who showed up during the pandemic eager to splurge."

Christie’s Sells $7.1 Billion in Art, the Highest in Five Years - WSJ (behind paywall) Meanwhile, Phillips reports $1.2 billion in sales as major auction houses credit influx of millennials and first-time buyers with propelling art sales

Leftist populist Gabriel Boric Wins Chile’s Presidential Election at Age 35

Will one of the most successful countries in terms of its economy go down the drain? Chile developed probably the best private free market economy of any of the large Latin American countries, but democracy is no guarantee to maintain such progress! The Miracle of Chile no more?

Too bad, Chile might follow down the wrong path of Venezuela, Brazil, Argentina!

Will the next wave of refugees from Chile not be fleeing a military junta, but a leftist tyranny causing poverty.

"He received 56% of the votes, handily defeating conservative rival José Antonio Kast, an immigration hardliner and ally of Brazilian President Jair Bolsonaro. Boric, a former student-protest leader, pledges to raise taxes to expand social services and dismantle a private pension system in Latin America’s richest nation"

Gabriel Boric Wins Chile’s Presidential Election at Age 35 - WSJ The leftist and former student protest leader pledges to raise taxes and dismantle a private pension system in Latin America’s richest nation

Flies Navigate Using Complex Mental Math

Amazing stuff!

"... Both teams showed that two types of brain cells (called PFNd and PFNv cells) track a fly’s heading (which way it’s facing) and its velocity (speed) as it walks. Since a fly has a nearly 360-degree field of vision ... to watch flies navigate in a 360-degree virtual reality environment. She improved on existing spherical treadmills for flies by adding an immersive virtual reality environment and placing the entire contraption in a clear plastic bubble, so that a camera underneath could record fly movement. By tracking neural activity as the fly navigated, the Wilson team found that both cell types are involved in making geometric calculations.

The neurons keep track of sideways and backward movements and register the compass direction in which the fly is moving. An animal could be facing north and walking forward, or facing west and walking to the right, Wilson says, and the brain would know that in both cases, the animal is actually moving in the same direction: northward.

That ability to adjust one’s orientation relative to both the body and the outside world is crucial for dead reckoning ...
discovered that the fly’s brain uses PFNd and PFNv cells to do this vector arithmetic. As the scientists report, a neural circuit in the fly brain can rotate, scale, and add the four vectors represented by different PFNd and PFNv populations to track the fly’s direction of travel relative to its body orientation.

To visualize this computation during flight, the researchers tethered flies to a platform in the center of a miniature arena and imaged their brains. Starlike dots displayed on the arena’s walls made the flies feel like they were traveling in various directions.

Inside the fly brain, activity patterns from PFNd and PFNv cell groups formed a sine wave, a type of regular, repeating wave that shows up often in physics and mathematics. The height and position of the waves vary depending on which way the fly was traveling, the team discovered. By adding the PFNd and PFNv waves, the fly was able to mathematically calculate if it was moving northward, eastward, etc. ..."

From the abstract of the 2nd paper:
"Many behavioural tasks require the manipulation of mathematical vectors, but, outside of computational models it is not known how brains perform vector operations. Here we show how the Drosophila central complex, a region implicated in goal-directed navigation, performs vector arithmetic. First, we describe a neural signal in the fan-shaped body that explicitly tracks the allocentric travelling angle of a fly, that is, the travelling angle in reference to external cues. Past work has identified neurons in Drosophila and mammals that track the heading angle of an animal referenced to external cues (for example, head direction cells), but this new signal illuminates how the sense of space is properly updated when travelling and heading angles differ (for example, when walking sideways). We then characterize a neuronal circuit that performs an egocentric-to-allocentric (that is, body-centred to world-centred) coordinate transformation and vector addition to compute the allocentric travelling direction. This circuit operates by mapping two-dimensional vectors onto sinusoidal patterns of activity across distinct neuronal populations, with the amplitude of the sinusoid representing the length of the vector and its phase representing the angle of the vector. ..."


Flies Navigate Using Complex Mental Math | HHMI For the first time, scientists have shown exactly how a fly brain creates a mental map of the body’s movement through the world.

Woman says she was virtually 'groped' in Facebook's VR metaverse, investigation launched

Crimes are committed in the real world and hither world! Why should virtual reality be any different? Such is human nature! Very difficult to escape!

Or is this part of a get rich quick scheme? Ah, human nature again! 😄

Facebook Meta company metaverse investigation into groping - TheBlaze

Will New York Times, Washington Post Return Pulitzer for Misleading Russia Collusion Stories?

Recommendable! Nice reminder that the history of print news media is littered with consequential fake stories! Unfortunately, the author of this article mentions only one such egregious historical fake story!

"In 1931, The New York Times published 13 articles by its Moscow reporter and Communist sympathizer, Walter Duranty, praising the Soviet Union and dictator Joseph Stalin’s government. These articles relied solely on official Soviet communist sources, ignored the evidence contradicting the government’s propaganda, and covered up the genocide Stalin was committing in the Ukraine."

Will New York Times, Washington Post Return Pulitzer for Misleading Russia Collusion Stories? | The Heritage Foundation

81 year old Anthony Fauci compares COVID-19 fight to World War II

Former President Trump made a huge mistake not to fire or retire this clown and charlatan Anthony Fauci!

Now we learn that this man is also delusional or suffers from a compulsive obsessive disorder! This man is crazy on a mission! Lord, have mercy with this fanatic!

The only thing the Faucian Bargain is correct about is that the draconian and largely unjustified broad measures taken by paternalistic Western governments are similar to those taken during war times!

Why SARS-CoV-2/Covid-19 is a relatively harmless disease and why the cure was worse than the disease.


"... "There's no way I’m going to walk away from this until we get this under control," Fauci responded. "We're in a war, John. It's kind of like we're halfway through World War II, and you decide, ‘I think I’ve had enough of this. I’m walking away.’ You can’t do that. You've gotta finish it. And we're gonna finish this and get back to normal." ..."

Fauci compares COVID-19 fight to World War II | Just The News

So called $1.2 trillion infrastructure bill U.S. Congress passed last month requires drunk driving prevention technology in all vehicles by 2026

Another bad idea by Big Government! This was also included in the so called infrastructure bill? How phony is that! Who voted for this!!!

This will surely make new vehicles more expensive beginning in 2026!
This is another foolish one size fits all measure! Many millions of drivers, who never or rarely drive while intoxicated have to pay for it! 
Is this technology even fool proof or reliable!
Lousy politics!

Such a measure should be targeted at drivers caught driving while under the influence of alcohol or drugs!

What about other drugs that impair driving? Will such preventative measures be next?

The attempt to compare this preventative measure with the introduction of mandatory airbags in 1991 is ridiculous! First of all this should not have been made mandatory (another Big Government measure to protect you from yourself). Second, airbags are so useful that most people would have voluntarily paid extra to have them installed in their car. 

"... The $1.2 trillion infrastructure bill that Congress passed last month requires drunk and impaired driving prevention technology as standard technology in vehicles as early as 2026. President Biden has signed the bill into law."

"... If successful, the law predicts, it could ultimately eliminate some 9,400 of the more than 10,000 drunken-driving deaths in the U.S. each year. ..."

Virginia testing in-car drunk driving prevention tech, could serve as national model | Just The News

Harvard moves to remote learning for three weeks in January, citing COVID-19

Why not online learning for a whole year in the digital age? Who needs all these traditional, legacy universities anymore?

Online learning would be a lot cheaper! Perhaps also less indoctrination with the leftist ideologies du jour!

"Harvard has a 97% vaccination rate, but school is still starting late in the spring, and students are required to receive booster vaccines."
Harvard moves to remote learning for three weeks in January, citing COVID-19 | Just The News

Janis Joplin - One Night Stand

Enjoy! Not sure I ever heard this song of her before. This video comes also with a nice selection of photos of her! 

Was that an early expression of Me Too? Quite possible!

When I am on the road playing in a town without a name ... catch me if you can

George Benson - Turn Your Love Around

Enjoy!

Teddy Pendergrass: Love T.K.O.

Enjoy! I think, I better let it go!

Teddy Pendergrass: Close the Door

Enjoy!

Tonight Is The Night - Betty Wright (1978)

Enjoy! I have not heard this song in a long time!

Sunday, December 19, 2021

Antonio Vivaldi CBC Documentary Steven Staryk Corey Cerovsek Ida Haendel

Very recommendable! I wish this video was remastered! A little bit odd is that the famous Four Seasons were not mentioned.

When scientists infected over a 1,000 dubiously selected people hepatitis for over 30 years

Some of the darker sides of science! The history of science is often inconvenient! In the name of science many terrible experiments were conducted over millennia!

Blind faith in science is wrong! Vigilance towards science is required at all times!

The current SARS-CoV-2/Covid-19 pandemic also taught us a few things: E.g. despite the fact that the disease is relatively harmless and severely affects mainly only a minority of people, the elderly and the immune compromised, governments now imposes vaccinations on children and young adults, the least affected! The cure has been worse than the disease!

The Global Warming hoax and the Climate Change religion is too a large part based on pseudo science!

"In 1942, in the grip of the Second World War, the US military faced an existential threat from within. A hepatitis outbreak was suspected to have infected hundreds of thousands of personnel.

There were no animal or cell-culture models for studying the viral liver disease. Desperate to find the source of the outbreak and learn how to contain it, the military joined forces with biomedical researchers, including some from the University of Pennsylvania in Philadelphia and Yale University in New Haven, Connecticut, to launch human experiments that continued for decades after the war.

During the 30-year programme — meticulously chronicled in Dangerous Medicine — researchers infected more than 1,000 people, including over 150 children, with viruses that cause hepatitis. The people enrolled were prison inmates, disabled children, people with severe mental illnesses, and conscientious objectors performing community service in lieu of fighting, relates historical sociologist Sydney Halpern. ..."

When scientists gave 1,000 vulnerable people hepatitis over 30 years What sort of system nurtures a decades-long programme of deliberately infecting children and prisoners with a dangerous disease?

Genetic Variant Discovered in Amish Protects from Heart Disease

Perhaps the antiquated lifestyle of the Amish people is good for your heart? (Just kidding)

Genetic Variant Discovered in Amish Protects from Heart Disease | The Scientist Magazine® Researchers link a missense mutation in the B4GALT1 gene to lower levels of LDL cholesterol and the blood clotting factor fibrinogen.

FDA Allows Women to Get Abortion Pill by Mail

In an effort to undermine the growing success of the pro life movement and e.g. restrictive legislation like in Texas!

It is already bad enough that delivery by mail of abortion pills has picked up after the Texas bill was passed according to news reports.

However, the the demented and senile 78 years old lifetime career politician, pseudo catholic, and chronic liar for decades, the 46th President of the U.S., who is probably also seriously compromised as far as his or his family’s dealings with Russia and China are concerned, has no scruples! Reckless and irresponsible policies by a demented president!

"The Food and Drug Administration announced Thursday that it will significantly weaken longstanding safety protocols that have applied to dangerous chemical abortion pills for more than 20 years, opening the door to widespread telemedicine abortion and abortion pill-by-mail distribution. ...
The chemical abortion pill regimen is a two-part process. The first pill, mifepristone (also known as RU-486 or its brand name, Mifeprex), causes the death of the unborn child by cutting off the hormone progesterone, which is required to sustain a pregnancy.

The second pill, misoprostol (brand name Cytotec), causes contractions to empty the uterus. The regimen is approved to be used for up to 70 days (10 weeks) into pregnancy.

The rate of chemical abortion has increased by 120% in the past decade, with roughly half of abortions today being chemical rather than surgical. ...
Since the Food and Drug Administration approved mifepristone in 2000, the drug has been associated with 26 deaths, thousands of serious adverse events, and more than 500 life-threatening complications (that we know of, due to lackluster state and federal reporting requirements)."

" ... The Food and Drug Administration decision to allow patients to get the drug mifepristone, sold under the brand name Mifeprex and sometimes known as RU-486, without a visit to a hospital or doctor will help pave the way for the drug to be available for ordering online and delivery by mail, according to groups that support abortion access. ..."

FDA Allows Women to Get Abortion Pill by Mail - WSJ (Behind paywall) The decision lifted a restriction requiring women to go to a medical office or hospital to pick up the mifepristone pills

Some Mammals have infrared antenna-like structures to detect predators

Amazing stuff!

"... The new research, published last week (December 8) ... builds on a body of unpublished evidence collected not by a biologist, but by a physicist, Ian Baker, who develops infrared sensors for a British defense company.
Baker has long brought his work home with him ... using infrared cameras containing his sensors to scan the fields and woods near his house in Southampton, England, for animals. A series of anecdotal observations—such as the fact that cats seem to “stack” their bodies behind their cold nose when hunting, along with a similar twisting behavior in swooping owls—led Baker to hypothesize that perhaps these predators “have to conceal their infrared to be able to catch a mouse,” in effect “hiding their heat.” ..."

From the abstract:
"Many small animals, including shrews, most rodents and some marsupials, have fur composed of at least four types of hair, all with distinctive and complex anatomy. A ubiquitous and unexplained feature is periodic, internal banding with spacing in the 6–12 µm range that hints at an underlying infrared function. One bristle-like form, called guard hair, has the correct shape and internal periodic patterns to function as an infrared antenna. Optical analysis of guard hair from a wide range of species shows precise tuning to the optimum wavelength for thermal imaging. For heavily predated, nocturnal animals the ability to sense local infrared sources has a clear survival advantage. The tuned antennae, spectral filters and waveguides present in guard hair, all operating at a scale similar to the infrared wavelength, could be a rich source of bio-inspiration in the field of photonics. The tools developed in this work may enable us to understand the other hair types and their evolution. ..."

Some Mammals May Use Specialized Hairs to Detect Predators' Heat | The Scientist Magazine® When observed under a microscope, guard hairs from mice resemble optical sensors used in thermal cameras to detect heat, according to a new study.

Tausende protestieren gegen Corona-Regeln in Deutschland

Update 21.12.2021:
Corona-Proteste reißen nicht ab: Zehntausende demonstrieren in Nürnberg, Saarbrücken und Thüringen Nachdem bereits über 10.000 Menschen in Hamburg demonstrierten, standen am Sonntag ebenso viele in Nürnberg auf den Straßen. Die Proteste erreichen immer mehr Menschen auch aus der Mitte der Gesellschaft. Von Jonas Aston


Wenn die Zahlen der Protestierer nicht so gering wären, würde ich fast sagen es tut sich ja mal was Positives in der Bananenrepublik!

Why SARS-CoV-2/Covid-19 is a relatively harmless disease and why the cure was worse than the disease.


Tausende protestieren gegen Corona-Regeln Im ganzen Land gehen Demonstranten auf die Straße, die sich an den Corona-Maßnahmen stören. Vielerorts formiert sich Gegenprotest.

Die Niederlande kehren zur Kernenergie zurück

Wird die Bananenrepublik etwas lernen von dem Nachbarland? Oder steckt die Bananenrepublik zu tief im Klimawahn, in der Kernenergie Psychose, und im Coronawahn?

Die Niederlande kehren zur Kernenergie zurück Die niederländische Regierung plant, zwei neue Atomkraftwerke zu bauen und das einzige bestehende länger in Betrieb zu halten. Als Grund gibt die neue Koalition unter Ministerpräsident Rutte den Klimawandel und die Versorgungssicherheit an.

Saturday, December 18, 2021

Facebook Admits ‘Fact Checks’ Are Actually ‘Opinion’

It only confirms what we knew all along from the beginning! So called fact checkers have been a propaganda tool, charade and phony!

"We now know that Facebook’s so-called “independent fact-checkers” are nothing of the sort. And we know this because Facebook admitted so in a response to Stossel’s defamation lawsuit.

According to Facebook, Stossel cannot sue the company for defamation because, “The labels themselves are neither false nor defamatory; to the contrary, they constitute protected opinion.” ..."

Facebook Admits ‘Fact Checks’ Are Actually ‘Opinion’ – RedState Outspoken libertarian journalist John Stossel, former ABC News correspondent, has become quite the thorn in the side of Facebook.

Hydrogen Fueled Life’s Origins

Amazing stuff!

"... But the metabolism of the planet’s first organisms may not have required an external source of energy. Under the conditions present in a hydrothermal vent, a core set of metabolic reactions unfolds spontaneously in line with the laws of thermodynamics ...
Hydrothermal vents, hot springs near fault lines on the ocean floor, were discovered 40 years ago, and soon after became recognized as environments conducive to the origin of life, as they are warm, rich with minerals, and contain physical and chemical gradients that facilitate reactions. In 2020, Martin and his group showed experimentally that, if kept in water in the presence of the nickel iron alloy awaruite overnight at 100°C, hydrogen gas (which is abundant in hydrothermal vents) will combine with carbon dioxide to form formate, acetate and pyruvate—the latter of which is one of the most central compounds of metabolism. Awaruite catalyzes the formation of pyruvate from hydrogen and carbon dioxide by acting as a reducing agent, allowing it to stand in for the suite of enzymes that usually construct the molecule stepwise in organisms. ...
Martin and his team had previously identified a core set of more than 400 metabolic reactions which would likely have been present in the Last Universal Common Ancestor (LUCA), the organism that gave rise to all extant life on Earth, and are needed to generate amino acids, nucleotides, and other essential cellular molecules. They next asked whether these reactions would have required an external energy source to proceed. 
To find out, the team calculated the Gibbs free energy for each reaction—a thermodynamic measure of the energy needed for or released from a chemical reaction, assuming the surrounding temperature and pressure are kept stable and there are no external inputs. It turns out that under the conditions present in hydrothermal vents, “almost all of the reactions in the metabolism of the last universal common ancestor are downhill,” says Martin—97 percent, to be exact. “That means there’s a natural tendency of metabolism to unfold all by itself, under the right conditions from the elements,” ... “You don’t have to add any energy. ..."

From the abstract:
"Though all theories for the origin of life require a source of energy to promote primordial chemical reactions, the nature of energy that drove the emergence of metabolism at origins is still debated. We reasoned that evidence for the nature of energy at origins should be preserved in the biochemical reactions of life itself, whereby changes in free energy, ΔG ... By calculating values of ΔG across the conserved and universal core of 402 individual reactions that synthesize amino acids, nucleotides and cofactors from H2, CO2, NH3, H2S and phosphate in modern cells, we find that 95–97% of these reactions are exergonic (ΔG ≤ 0 kJ⋅mol−1) at pH 7-10 and 80-100°C under nonequilibrium conditions with H2 replacing biochemical reductants. While 23% of the core’s reactions involve ATP hydrolysis, 77% are ATP-independent, thermodynamically driven by ΔG of reactions involving carbon bonds. We identified 174 reactions that are exergonic by –20 to –300 kJ⋅mol−1 at pH 9 and 80°C and that fall into ten reaction types: six pterin dependent alkyl or acyl transfers, ten S-adenosylmethionine dependent alkyl transfers, four acyl phosphate hydrolyses, 14 thioester hydrolyses, 30 decarboxylations, 35 ring closure reactions, 31 aromatic ring formations, and 44 carbon reductions by reduced nicotinamide, flavins, ferredoxin, or formate. The 402 reactions of the biosynthetic core trace to the last universal common ancestor (LUCA), and reveal that synthesis of LUCA’s chemical constituents required no external energy inputs such as electric discharge, UV-light or phosphide minerals. The biosynthetic reactions of LUCA uncover a natural thermodynamic tendency of metabolism to unfold from energy released by reactions of H2, CO2, NH3, H2S, and phosphate."

Hydrogen Fueled Life’s Origins: Study | The Scientist Magazine® A thermodynamic analysis of more than 400 chemical reactions that likely took place in the ancestor of all life finds most would spontaneously occur at hydrothermal vents, thanks to the hydrogen these geological formations emit.

Ex-FDA officials, medical experts flog feds for politicizing COVID, misrepresenting evidence

Recommendable! A long list of recent federal government failures regarding Covid-19!

No wonder with a clown and charlatan like Anthony Fauci and others at the helm! See also my blog about this creme de la creme of the U.S. medical establishment!

Why SARS-CoV-2/Covid-19 is a relatively harmless disease and why the cure was worse than the disease.


Ex-FDA officials, medical experts flog feds for politicizing COVID, misrepresenting evidence | Just The News

Research finds potential mechanism linking autism, intestinal inflammation

Good news! A long and comprehensive article! This research is all based on mouse models.


"Though many people with autism spectrum disorders also experience unusual gastrointestinal inflammation, scientists have not established how those conditions might be linked. Now MIT and Harvard Medical School researchers, working with mouse models, may have found the connection: When a mother experiences an infection during pregnancy and her immune system produces elevated levels of the molecule Interleukin-17a (IL-17a), this can not only alter brain development in her fetus, but also alter her microbiome such that after birth the newborn’s immune system can become primed for future inflammatory attacks. ..."

From the abstract:
"Children with autism spectrum disorders often display dysregulated immune responses and related gastrointestinal symptoms. However, the underlying mechanisms leading to the development of both phenotypes have not been elucidated. Here, we show that mouse offspring exhibiting autism-like phenotypes due to prenatal exposure to maternal inflammation were more susceptible to developing intestinal inflammation following challenges later in life. In contrast to its prenatal role in neurodevelopmental phenotypes, interleukin-17A (IL-17A) generated immune-primed phenotypes in offspring through changes in the maternal gut microbiota that led to postnatal alterations in the chromatin landscape of naive CD4+ T cells. The transfer of stool samples from pregnant mice with enhanced IL-17A responses into germ-free dams produced immune-primed phenotypes in offspring. Our study provides mechanistic insights into why children exposed to heightened inflammation in the womb might have an increased risk of developing inflammatory diseases in addition to neurodevelopmental disorders."

Research finds potential mechanism linking autism, intestinal inflammation | MIT News | Massachusetts Institute of Technology Infection during pregnancy with elevated levels of the cytokine IL-17a may yield microbiome alterations that prime offspring for aberrant immune responses, mouse study suggests.

Friday, December 17, 2021

NASA's Parker Solar Probe Touches The Sun For The First Time

We still now so little about the sun! This is one major reason why Global Warming is a hoax and Climate Change a religion!

World’s first autonomous rig drills first well in Permian Basin

Good news!

Could robots replace roughnecks? World’s first autonomous rig drills first well in Permian Basin (behind paywall)



Ein europäischer Mindestlohn?

Was für ein Irrsinn! Typisch Ursula von der Leyen! Die Wirtschaften der EU  Mitgliedsländer sind viel zu verschieden!

Staatliche Preiskontrollen sind abzuschaffen!

Schlimm genug, dass die Deutschen einen Mindestlohn unter der SED Kanzlerin Merkel eingeführt haben!

"Schon bei der Debatte um den nationalen Mindestlohn driften die Meinungen gehörig auseinander. Auf EU-Ebene wird seit mehr als einem Jahr allerdings ein viel größerer Schritt diskutiert: die Einführung eines europäischen Mindestlohns. Als Richtlinienentwurf vorgelegt wurde die Idee bereits Ende 2020, umgesetzt ist sie bis heute jedoch nicht"

Ein europäischer Mindestlohn? - iwd.de

Generosity in Canada is declining

To measure generosity only by tax records is probably to narrow and misses other donations!

"Nationally, the percentage of Canadian tax filers donating to charity has fallen over the last decade from 23.1% in 2009 to 19.0% in 2019.
The percentage of aggregate income donated to charity by Canadian tax filers has also decreased from 0.58% in 2009 to 0.53% in 2019.
This decline in generosity in Canada undoubtedly limits the ability of Canadian charities to improve the quality of life in their communities and beyond."

"... The study also finds that the total amount donated by Canadians during the 2019 tax year—just 0.53 per cent of income—is the second lowest amount since at least 2000. During that period, Canadians’ generosity peaked at 0.72 per cent in 2006, before declining in subsequent years. ..."

Generosity in Canada: The 2021 Generosity Index | Fraser Institute

Car break-ins are so rampant in San Francisco that residents are leaving their trunks wide open to ward off burglars

This is what you get when you are soft on crime and when you defund the police and when prosecutors letting criminals go on bail etc.! When criminals are seen as victims of society etc.!

Car break-ins are so rampant in San Francisco that residents are leaving their trunks wide open to ward off burglars - TheBlaze

Bundeskanzler Olaf Scholz verspricht nichts Gutes in Regierungserklärung

Ob Scholz ein besserer Kanzler sein wird als die unsägliche SED Kanzlerin Merkel ist zweifelhaft! Seine Regierungserklärung lässt schlimmes befürchten! Hatte leider keine Zeit seine ganze Regierungserklärung zu lesen!

Klimawahn und Coronawahn umnebeln auch diesen mittelmäßigen lebenslangen Berufspolitiker!

Sozialistischer Machbarkeitswahn! Niemand weiß was in der Zukunft passiert! Was für eine Anmaßung von Wissen!
„Vor uns liegen große Aufgaben“, sagte Scholz, der von der „größten Transformation unserer Industrie und Ökonomie seit mindestens hundert Jahren ...
Weichenstellungen, die wir jetzt vornehmen, weil wir jetzt den richtigen Kurs (???) in die Zukunft einschlagen müssen. ...“ 

Scholz's Mein Kampf! Von einem Kampf gegen eine Krankheit zu sprechen ist schlimm, völlig daneben! Wir müssen wahrscheinlich noch viele Jahre mit der relativ harmlosen Corona leben so wie mit Erkältung und Grippe! Sieg gegen Corona is daher völlig vermessen! Corona ist keine Krise!
"Ja, wir werden den Kampf gegen diese Pandemie mit der größten Entschlossenheit führen. Und ja, wir werden diesen Kampf gewinnen. Wir werden die Krise überwinden. ...
Jeder kann und sollte sich regelmäßig testen. Wir alle sollten unsere Kontakte weiter behutsam einschränken. Aber am allerwichtigsten ist: Jeder kann und sollte sich impfen lassen. Darum geht es mir. ...
Ich möchte, dass wir alle zusammen in Deutschland 30 Millionen Impfdosen bis
Jahresende in die Oberarme kriegen, als erste Impfung, als zweite Impfung und als Boosterimpfung. ...
Es ist mir wichtig, dass wir es weiter gemeinsam angehen, dass wir uns weiter unterhaken und so Corona besiegen
Deshalb habe ich einen Krisenstab aufgebaut, der aus dem Kanzleramt heraus jeden Tag neu die Lage bewertet und auch handelt. Er wird von einem erfahrenen General geleitet ...
Wir werden alles tun, was notwendig ist. Es gibt da für die Bundesregierung keine roten Linien. (Wie bitte!!!) ..."

Weiss der Depp Scholz nicht, dass auch Deutschland Herdenimmunität (über 67% geimpfte und genesene Erwachsene) etwa im Juli 2021 erreicht hat! Z.B. die ältere und höchst anfällige Bevölkerung ist über 80% oder so geimpft! Wovon schwätzt dieser Berufspolitiker!!! Warum muss jeder geimpft sein???? Die Ungeimpften werden beschuldigt und wie Aussätzige behandelt!
"... Zur Wahrheit dieser Pandemie gehört aber auch: Heute, im Dezember 2021, könnte jede und jeder Erwachsene in Deutschland längst zweifach geimpft sein. Mindestens alle besonders gefährdeten Bürgerinnen und Bürger könnten geboostert sein. Dann hätten wir die Pandemie jetzt im Griff. Dann würden wir alle jetzt mit unseren alten Freiheiten und unseren Familien und Freunden eine besinnliche Vorweihnachtszeit erleben. Die Kraft des wissenschaftlichen Fortschritts hätte uns genau das ermöglicht. ..."

Deutscher Bundestag - Bundeskanzler Olaf Scholz verspricht „Aufbruch und Fortschritt“

Europe’s Top Central Banks Take Divergent Tracks as They Confront Inflation

Finally and several years too late Western central banks are reversing the reckless and irresponsible extremely loose monetary policy and extremely low interest rates since 2009! Public and private debt accumulation became too cheap since 2009.

Cheap money can lead to binge buying!

The advantages of Brexit!

"Europe’s foremost central banks took diverging policy paths a day after the Federal Reserve set the stage for rate rises in 2022, differing approaches that underscore the challenges for policy makers as they balance surging inflation and renewed risks to growth from the fast-spreading Omicron variant of the coronavirus.

The Bank of England became the first of the world’s major central banks to raise its benchmark interest rate since the pandemic began, while the European Central Bank said it would phase out an emergency bond-buying program while ramping up other stimulus measures to keep the 19-nation eurozone’s recovery on track. ..."

Europe’s Top Central Banks Take Divergent Tracks as They Confront Inflation - WSJ After Fed signal of future rate rises, Bank of England raises benchmark rate and ECB says increase in 2022 is very unlikely

New UK free trade agreement with Australia covers 75 per cent of Australian exports

Good news! Brexit keeps on giving!

Thomas Sowell: Where Current Black Culture Really Comes From

Very recommendable! Food for though!

Thursday, December 16, 2021

Russia: An International Hub for Private Armies

Very recommendable! Putin the Terrible used mercenaries to invade and annex Crimea in 2014.

The ancient 'computer' from about 100 BC that simply shouldn't exist

Very recommendable! I remember having learnt about this device (Antikythera mechanism) many years ago.
Too bad, apparently we have not yet discovered another device like it.

Obedience to Authority: A Controversial Experiment from 1963

These type of psychological or behavioral experiments are probably not possible anymore today because of ethics concerns etc. However, are the results of this research in serious doubt?

The researcher, Stanley Milgram, also tried to link the research result to Nazis committing the Holocaust!

"The Milgram experiment(s) on obedience to authority figures was a series of social psychology experiments conducted by Yale University psychologist Stanley Milgram. They measured the willingness of study participants, men 20–50 years old from a diverse range of occupations with varying levels of education, to obey an authority figure who instructed them to perform acts conflicting with their personal conscience. Participants were led to believe that they were assisting an unrelated experiment, in which they had to administer electric shocks to a "learner". These fake electric shocks gradually increased to levels that would have been fatal had they been real.

The experiment found, unexpectedly, that a very high proportion [65%] of subjects would fully obey the instructions, albeit reluctantly. Milgram first described his research in a 1963 article in the Journal of Abnormal and Social Psychology and later discussed his findings in greater depth in his 1974 book, Obedience to Authority: An Experimental View. ...
On June 10, 1964, the American Psychologist published a brief but influential article by Diana Baumrind titled "Some Thoughts on Ethics of Research: After Reading Milgram's' Behavioral Study of Obedience.'" Baumrind's criticisms of the treatment of human participants in Milgram's studies stimulated a thorough revision of the ethical standards of psychological research. She argued that even though Milgram had obtained informed consent, he was still ethically responsible to ensure their well-being. When participants displayed signs of distress such as sweating and trembling, the experimenter should have stepped in and halted the experiment. ..."

Milgram experiment

Credits: The Experiment That Shook the World

UAE told US it will suspend talks on F-35 jets and other advanced weapons deal worth $23 billion

This could have serious ramifications for future sales of advanced U.S. weapons!

"The United Arab Emirates has informed the United States that it will suspend discussions to acquire F-35 fighter jets, a UAE official said on Tuesday, part of a $23 billion deal with the ally that also includes drones and other advanced munitions.
The sale of 50 F-35 warplanes made by Lockheed Martin to the UAE had slowed amid concerns in Washington over Abu Dhabi's relationship with China, including the use of Huawei 5G technology in the country. "Technical requirements, sovereign operational restrictions, and cost/benefit analysis led to the re-assessment," the UAE official said in a statement to Reuters that confirmed a report in The Wall Street Journal. ..."

UAE told US it will suspend talks on F-35 jets - Emirati official - The Jerusalem Post The sale of 50 F-35 warplanes made by Lockheed Martin to the UAE had slowed amid concerns in Washington over Abu Dhabi's relationship with China.

Anonymous Whistleblower letter dated 11/10/2020 alleges thousands of fraudulent votes in Pima County, Arizona

The November 2020 U.S. election is not over yet! If this is corroborated, then this is more evidence that the frequently tight election results were tampered with! 

Remember, the 46th President won by less than 12,000 votes in Arizona!

However, 35,000 fraudulent votes (or even multiples) in one county with about 1.1 million total population is extremely high to believe it.

"... The letter, dated Nov. 10, 2020, and addressed to the Criminal Division of the Justice Department, describes a plan orchestrated by the Pima County Recorder and Democratic Party to add approximately 35,000 fraudulent votes to the vote total of each Democratic candidate on the ballot in Pima ..."

Whistleblower letter alleges thousands of fraudulent votes in Pima County, Arizona | Just The News The letter addressed to DOJ was read into the record at a recent [Pima county] election integrity hearing

Microschooling thrives in Arizona

Good news! Why federalism and decentralization of government is so important! It is high time to privatize the education of our children!

"Microschools, small schools that educate five to 15 students, have been among the most interesting recent developments in the K–12 reform world. Neither homeschooling nor traditional schooling, they exist in a hard-to-classify space between formal and informal learning environments. They rose in popularity during the pandemic as families sought alternative educational options that could meet social-distancing recommendations. But what they offer in terms of personalization, community building, schedules, calendars, and the delivery of instruction will have appeal long after Covid recedes.

One of the most prominent microschooling networks, Prenda, was founded in 2018 in Mesa, Arizona’s third largest city. It has experienced dramatic growth largely because of the way it attracts parents like those interviewed for this paper. It is no coincidence that Prenda’s emergence and expansion took place in Arizona, which has been a national leader in education innovation for a generation. Arizona’s cultural and policy environment foster and promote experimentation, diversification, and parental choice. The state’s thriving charter-school sector—no state has a higher percentage of students in charters—has developed an expansive, varied set of choice-based public schools. For decades, Arizona’s traditional public schools have been part of the state’s open-enrollment system, making more than a thousand district-run schools part of a choice system. And Arizona has been a national leader on private-school choice, passing the nation’s first “education savings account” program and today, via an array of state programs, enabling more than 100,000 students to access nonpublic schools. ..."

How Years of Policy Choices Enabled Microschooling to Thrive in Arizona | Manhattan Institute

Alice Weidel ZERLEGT die Ampel!

Empfehlenswert! Bravo Frau Weidel! Die AfD ist die einzig wählbare Partei in der Bananenrepublik Deutschland!

President Reagan and Friends: Pope John Paul II

Recommendable!
These are rare moments in history when great minds meet and think alike! But with President Reagan, Pope John Paul II, Prime Minister Thatcher, and Lech Walesa such a moment was witnessed and human progress was advanced!

Wednesday, December 15, 2021

John Stossel: Abolish the FDA?

Recommendable! For decades, the FDA has been way too slow to approve new drugs! The standard of efficacy should be dropped! The right to try should be emphasized!

Florida Governor DeSantis unveils SWEEPING anti-WOKE legislation, protects workers, students

Recommendable! Bravo DeSantis! 

Horror images from inside North Korea taken in 2020

This Magnum photographer, who spent 60 days in North Korea, is a moron!

Vagina microbiome: The Most Secret Garden

Amazing stuff!

"... Just like the gut microbiome, the vaginal microbiome varies across populations and, thanks to shifting hormone levels, across life stages and even within the menstrual cycle. Although inventories conducted of vaginal flora have identified numerous bacterial taxa, “there’s been a lack of attempt to understand the vaginal microbiome as an ecosystem,” ... “Women can have very different vaginal microbiome types. If you took a vaginal swab from any number of people at Radcliffe, you would find differently structured vaginal microbiomes.”
This variation in flora complicates general statements about what makes a healthy or asymptomatic vagina—and it also complicates the efficacy of treatments for disorders such as bacterial vaginosis (BV), estimated to affect a quarter of women worldwide, usually during their reproductive years. Aside from causing pain and discomfort, BV makes women more susceptible to sexually transmitted diseases and has been linked to preterm birth and low birth weight. ..."

The Most Secret Garden | Radcliffe Institute for Advanced Study at Harvard University Of all the body’s microbiomes, the vagina’s is perhaps the least understood. In hopes of informing better therapies for vaginal health, the microbial ecologist Libusha Kelly is conducting research that could change that.

January 6 committee admits to altering text message between Mark Meadows and Jim Jordan

U.S. Representative Adam Schiff should have been censured a long time ago if not indicted! He is a criminal and a habitual liar! His ugly and long crusade against former President Trump based on the Russian hoax was almost like Stalinist purges and nobody stopped this guy! He is one of the faces of the Trump Derangement Syndrome! He would say anything!

The January 6th committee is more like a kangaroo court!

"... A spokesman said Wednesday that the graphics Rep. Adam Schiff showed during a Monday-night hearing about the newly obtained communications between top Trump officials had been reformatted to support the view that Meadows wanted Pence to overturn the election results. ..."

Jan. 6 committee admits to altering text message between Mark Meadows and Jim Jordan | Washington Examiner



4 strategies for sustainable business | MIT Sloan

Major business school tries to force private businesses to have outside political and ideological activists or international organisations to run your company!

What kind of a business school is this? Bizarre!

"
1. Listen, internally and externally (includes BLM)
2. Deploy overlapping timelines (to eliminate plastic)
3. Develop a mix of metrics (is your supply chain partner a member of the U.N. Global Compact)
4. Connect sustainability with diversity, equity, inclusion, and justice

"Climate change is necessarily a justice issue": Jason Jay Co-director, MIT Sloan Sustainability Initiative
"
4 strategies for sustainable business | MIT Sloan Companies are under pressure from multiple stakeholders to adopt sustainable business practices. Here are four foundational tenets to guide your strategy.

Stretchy electronics go wireless

Recommendable! Seems to be a winning combination! Stretch me not! :-)

Could Mongolia have been the next Dubai?

Recommendable! The curse of a natural resources rich country?

Should We End the Fed?

Very recommendable! Since the dawn of digital currency is upon us this is some important food for thought!

The real story behind Archimedes’ Eureka!

Very recommendable! Learn about the ancient Titanic and the law of buoyancy!

White House cut video feed of transgender Taiwanese minister at Biden Summit for Democracy

So incredible! What a phony Summit this was, but Western media were gushing and glowing about it!

What more will the citizens of the world have to suffer through by the the demented and senile 78 years old lifetime career politician and chronic liar for decades, the 46th President of the U.S., who is probably also seriously compromised as far as his or his family’s dealings with Russia and China are concerned.

"The White House abruptly shut off the video feed of a Taiwanese minister during last week’s Summit for Democracy when she displayed a map indicating Taiwan was independent of China, according to a report on Monday. 

The image of the presentation by Taiwanese Digital Minister Audrey Tang was pulled and replaced with audio on orders from the White House, Reuters reported.

The report, citing sources, said the White House became concerned that Tang’s map appeared to be at odds with Washington’s “one China” policy, which acknowledges but does not take a position on China’s claim that Taiwan is part of its territory. ..."

WH cut video feed of Taiwanese minister at Biden summit: report

Here is the more detailed story by Reuters:



Tuesday, December 14, 2021

Former President Trump Hints at 2024 Run, Says He Likes Florida Governor DeSantis ‘A Lot’

Former President Trump would make a very smart move not to run again in 2024, but to help groom the next successful contender in the 2024 U.S. presidential election.

"Former President Donald Trump again hinted at a 2024 presidential run during his “History Tour” with Bill O’Reilly in Orlando on Sunday.

“We won the first time, and the second time we won by even more. And it looks like we might have to think about very strongly a third time,” Trump told O’Reilly before a crowd in the Amway Center. ..."

Trump Hints at 2024 Run, Says He Likes DeSantis ‘A Lot’

Larry Nassar sexual abuse victims reach $380 million settlement with USA Gymnastics, US Olympic Committee and insurers

How is this even possible that this gymnastics physician got away from 1986 to 2016 with sexually abusing hundreds of female teenagers and young women? Earliest complaints date back to the 1990s.

Did e.g. the parents, or colleagues or others not notice anything over the decades? Who were the enablers of this horrific crime? Why did the athletes not refuse to be treated any longer by this predator?

Did this enormous long lasting breakdown occur because of the competitive environment and the quest for fame etc. was more important?

Larry Nassar victims reach $380 million settlement with USA Gymnastics, US Olympic Committee and insurers - CNN

Naftali Bennett becomes first Israeli prime minister to visit the United Arab Emirates

Good news! Blessed are the peacemakers! President Trump's Abraham Accords keep on giving!

Finally, peace and prosperity in the Middle East!

"Israeli Prime Minister Naftali Bennett met with Mohammed bin Zayed al-Nahyan, the Crown Prince and leader of the United Arab Emirates Monday, marking the first time an Israeli prime minister has visited the country.
The trip was announced by Bennett’s office just a few hours before he flew to the Gulf country Sunday. ..."

Naftali Bennett becomes first Israeli prime minister to visit the United Arab Emirates - Jewish Telegraphic Agency



Keine Testpflicht? Freiheit für die, die sie verdienen

Was für ein Depp dieser Redakteur der FAZ! Die massiven Einschränkungen der individuellen Freiheit sind viel zu weit gegangen, waren ungerechtfertigt, und verfassungswidrig! 

Nur 76 Jahre oder etwa zwei Generationen nach Hitler haben die deutschen Politiker schon den Nazi Terror und seine Lehren völlig vergessen! Sehr bedenklich!

Hier ist mein blog zur unmenschlichen Sprache unserer Covid-19 Zeit!

Why SARS-CoV-2/Covid-19 is a relatively harmless disease and why the cure was worse than the disease.


Keine Testpflicht? Freiheit für die, die sie verdienen Wer im Kampf gegen Corona Totalitarismus am Werk sieht, hat ein grundsätzliches Problem mit unserer freiheitlichen Ordnung. Dabei braucht die jede Stimme.

Woman Charged in Alleged Theft of over $300K in Items from California Stores

Another facet of gender equality! Me too! Equal pay for equal crime? When will we learn about a female gangster boss like Al Capone? (Caution: Irony)

Woman Charged in Alleged Theft of over $300K in Items from CA Stores A woman has been charged with several felonies for taking items worth over $328,000 from Nordstrom Rack and TJ Maxx shops in Orange County, California.

Jill Biden Says Old Joe Biden is Sharp as a Tack. She Wouldn't Lie, Would She?

I blogged here on November 9th, 2021 that I believe Ms. Biden is complicit in the cover up if not more of perhaps the worst political scandal since Watergate!

That interview with the First Lady is somewhat pathetic! She comes across as lethargic and conflicted!

The lame and tame journalist did not follow up at all!

"... In a portion released Thursday of a CBS Sunday Morning interview that will run this weekend, CBS’s Rita Braver noted that “quite a few Americans have some questions about the president’s current mental fitness.” The winsome Dr. Jill snapped back, “I think that’s ridiculous.” ..."

Jill Biden Says Old Joe Biden is Sharp as a Tack. She Wouldn't Lie, Would She? | Frontpagemag