The third study is a first stab at working H. longi into human evolution. The authors created a new phylogenetic tree for the Homo lineage using 95 fossils and more than 600 measurements and morphological traits and modeled the presumed biogeographic migrations of different groups during the Pleistocene. The resulting tree confirmed that the Harbin cranium, along with other fossils from the Harbin group, constitute a monophyletic sister lineage with H. sapiens, pushing the time when modern humans and Neanderthals last shared a common ancestor back 400,000 more years and displacing them as our most recent ancestor. ..."
In honor of Thomas Paine and other Founders & Immigrants. In memory of my daddy Horst Bingel and my mom Irma Bingel
Tuesday, July 06, 2021
"Dragon Man" May Replace Neanderthal as Our Closest Relative
The third study is a first stab at working H. longi into human evolution. The authors created a new phylogenetic tree for the Homo lineage using 95 fossils and more than 600 measurements and morphological traits and modeled the presumed biogeographic migrations of different groups during the Pleistocene. The resulting tree confirmed that the Harbin cranium, along with other fossils from the Harbin group, constitute a monophyletic sister lineage with H. sapiens, pushing the time when modern humans and Neanderthals last shared a common ancestor back 400,000 more years and displacing them as our most recent ancestor. ..."
Research advances one step closer to stem cell therapy for type 1 diabetes
Why the Fourth of July Belongs to Thomas Jefferson by Lawrence Reed
Sieben Großstädte in Deutschland wollen großflächig Tempo 30 testen
Monday, July 05, 2021
Ukraine Inks Infrastructure Deal with China After Biden Snubs Zelensky for Putin
The Zelensky administration’s abrupt shift in attitude towards Chinese investment follows the president’s condemnation of American counterpart Joe Biden last month for failing to impose sanctions on Russia’s Nordstream 2 fuel pipeline. ...
Biden rejected an urgent request from Zelensky to meet in person prior to his summit with Russian leader Vladimir Putin on June 16. Shortly after meeting Putin, Washington, DC, publications began to report that Biden had chosen to freeze lethal aid to Ukraine, pivotal in the eastern Donbass war against Russian allied militias. ..."
Chinese scientists deleted key data that could help identify origins of COVID-19
But when [the researcher] went to the SRA [NIH's Sequence Read Archive] to examine the Chinese sequences, he found the data had been deleted. He explained in his paper that the SRA "is designed as a permanent archive of deep sequencing data." The only circumstances under which data can be removed is if the original researchers make an email request to have it deleted, provide reasons for doing so, and have that request approved by SRA staff. ...
Polish-Lithuanian Commonwealth’s Legacy of Liberty by Lawrence Reed
- Election was the only route to the throne, and no children of the elected monarch could inherit the position.
- The King could not raise taxes or tariffs, declare war or impose a military draft, without the approval of Parliament, known then as it is today as the Sejm. He couldn’t even get married unless the Sejm signed on (in those days, royal marriages were a foreign policy matter).
- ... the King could not rule without endorsement of the Sejm, which he was required to convene at least once every two years for a minimum of six weeks.
- The King was compelled to enforce the religious freedom guarantees that made the Commonwealth one of the most tolerant enclaves on the European continent ...
- The nobles jealously guarded not only their own positions, but the freedoms of the people more broadly. ... each king had to take an oath that embodied these words: “If anything has been done by us against laws, liberties, privileges or customs, we declare all the inhabitants of the Kingdom are freed from obedience to us.”
Israel Aerospace is selling dozens of its Drone Guard system to a South Asian country
With hundreds of units already operational across the world, the multi sensor, multi-layer Drone-Guard system provides an efficient solution for drone attack threat. ..."
Chinese Scientists Produce Genetically Modified Pigs for Human Transplant
In 2017, eGenesis announced that it had produced the world’s first genetically modified pigs that do not carry endogenous retroviruses, eliminating the risk of virus transmission from pigs to humans; and in 2018, eGenesis produced the first immunoplex-engineered pig, reducing the immune rejection of pig allogeneic organ transplants. ..."
In this study, we improved the scale of porcine germline editing from targeting a single repetitive locus with CRISPR to engineering 13 different genes using multiple genome engineering methods. ..."
Keystone XL Pipeline Developer Seeks $15 Billion in Damages From US
Hyperschall-Waffen - Wundermittel oder überschätzte Technologie?
Hubert Aiwanger: Es darf keinen Druck auf Ungeimpfte geben
How COVID-19 vaccines were made so quickly without cutting corners
It began with deciphering the exact genetic makeup of SARS-CoV-2, the virus that causes COVID-19. By early January 2020, that genetic blueprint was in hand and the first vaccines to test were ready just a few weeks later. ...
Researchers knew to zero in on those [spike] proteins thanks to decades of work studying coronaviruses, including two that have caused other outbreaks of human diseases — SARS and MERS. That work also identified the best form of the protein to use: a stable form just before the virus fuses with a cell it’s about to infect. ...
Scientists had already built these rapid, genetically based templates largely because of the ongoing battle against HIV ...
“plug-and-play” vaccine manufacturing. Decades of trying to attack HIV has created a library of safe [templates] to use quickly against any new would-be viral marauders. ...
The Secret Of The Mona Lisa: Da Vinci's Most Famous Smile
Sunday, July 04, 2021
Pseudoscience: People who have had COVID-19 may require only single dose of two-dose vaccines
Software development in the age of artificial intelligence
The dust has not yet settled. Research in this area is still nascent. However, it is already apparent that software development and engineering will undergo a revolution and dramatic changes!
Sooner than later, machine learning will write software programs to solve all kinds of tasks better than any human developer or developer team.
Here is just one example of a very recent research paper in this in this very active research area:
Leveraging Language to Learn Program Abstractions and Search Heuristics (one of the authors, Joshua B. Tenenbaum, is a highly cited professor at MIT)
Biden kneels before Orthodox adviser to Israel's president after learning she has 12 children
Frederick Douglass’ Other Fourth of July Speech Is Particularly Timely in 2021
Scientists reveal how internal biological clock may suppress tumor growth
Now, new research ... demonstrates a clear link between the circadian clock and the body’s tumor suppression system, with the potential to accelerate cancer cell growth. ...
the new research shows how mutant forms of the circadian clock gene CRY2 found in human tumors are able to dampen the activity of a key tumor suppressor gene, P53. ...
“This is the first study to investigate point mutations in a core clock gene that have been reported in human cancers,” ... “The impact of these genetic changes on P53 activity is truly remarkable and indicates a striking regulation of tumor suppression by the circadian clock.” ..."
Disruption of circadian rhythms increases the risk of several types of cancer. Mammalian cryptochromes (CRY1 and CRY2) are circadian transcriptional repressors that are related to DNA-repair enzymes. While CRYs lack DNA-repair activity, they modulate the transcriptional response to DNA damage, and CRY2 can promote SKP1 cullin 1–F-box (SCF)FBXL3-mediated ubiquitination of c-MYC and other targets. Here, we characterize five mutations in CRY2 observed in human cancers in The Cancer Genome Atlas. We demonstrate that two orthologous mutations of mouse CRY2 (D325H and S510L) accelerate the growth of primary mouse fibroblasts expressing high levels of c-MYC."
India looks westwards towards Pakistan to counter China
In recent weeks, there have been reports of secret back-channel talks between Indian and Pakistani security officials—facilitated by the United Arab Emirates—aimed at easing bilateral tensions. A February 2021 ceasefire along the Line of Control separating Indian and Pakistani forces in the disputed Kashmir region has so far held, permitting an atmosphere of near-normality in the area. ..."
How plants quickly adapt to shifting environmental conditions
“This paper shows, in high resolution, how plants respond to subtle environmental changes on the cellular level,” ...
Stichtag 3. Juli: Das Einwegplastik-Verbot tritt in Kraft
Ohio to Send 185 National Guard Members to Southern Border
India's Beautiful Musical Traditions
AfD: Ein Drittel aller Sozialleistungen gehen an Nicht-Deutsche!
Saturday, July 03, 2021
A Virtual Tour of the Mütter Museum in Philadelphia
'Evidence Strongly Favors The Lab Origin': GOP-Called Medical Witness Richard Muller
History's judgement on the global Covid-19 pandemic will not be kind!
This global Covid-19 pandemic has, for all people to notice, exposed and revealed how foolish most of our elected politicians and how inept most of our influential elites are! A total failure of common sense, reason, and rationality! Like lemmings, these politicians and elites were running over the cliff with Covid-19!
The emperor's new clothes (has no clothes) as far as the government responses to Covid-19 are concerned!
So many grave errors were made for over 1.5 years and they were not corrected!
Politicians and the elite allowed a hysteria to go on and fester for over 1.5 years! Sound advice like we have nothing to fear, but fear itself was totally forgotten!
Latest by June 2020, it was clear that Covid-19 is very infectious, but relatively harmless! E.g. young and healthy people were rarely affected and so on.
The lab leak hypothesis was entirely dismissed until late Spring 2021. China was not pressured for more cooperation and so on!
The death toll attributed to Covid-19 was totally inflated and never corrected! I bet, it is at least 50% inflated!
Instead of focusing our efforts on the vulnerable people, the entire populations and all businesses were subjected to Draconian, one size fits all measures like lockdown, which were upheld for 12 months and longer, and so forth!
Retraction of paper on vaccine deaths spurs call for more scrutiny of COVID-19 death reports
“Bad fat” suppresses killer T cells from attacking cancer
suggests new pathways for safeguarding the immune system’s ability to fight cancer by reducing the oxidative lipid damage in killer T cells. ...
established that tumors contain elevated amounts of several classes of lipid, and oxidized lipids in particular, which are generally found in oxidized low-density lipoproteins (LDLs), commonly considered “bad” fat. They then observed how killer T cells respond to the oxidized LDLs in tumors and found that killer T cells adapted to the tumor microenvironment by increasing CD36 on their surface and ingesting an abundance of oxidized lipids. ... they found this process served as a catalyst to drive even greater amounts of lipid oxidation internally in the killer T cells and ultimately repressed their defenses. ..."
Dinoflagellate Genome Structure Unlike Any Other Known
Dinoflagellates are best known for their relationship to corals. In exchange for a safe home, the single-cell microalgae provide the coral with photosynthetic nutrients. When corals bleach, it’s because they’re expelling their symbionts in response to stress. ...
Biden's Bureau of Land Management nominee is an unabashed eco-terrorist
This is the same Tracy Stone-Manning who wrote a graduate student thesis for the University of Montana, titled “Into the heart of the beast. A case for environmental advertising,” in 1992.
“We must consume less, and more importantly, we must breed fewer consuming humans.”..."
Maybe she is a Kamala Harris clone!
Pakistan – journey through a land of contrasts
Friday, July 02, 2021
Klimahysteriker kochen vor Wut: CO2 nicht schuld an "Klimaerhitzung"!
Japan's Bet on Energy Independence
National Geographic: When vaccination was ‘a badge of honor’
Accelerating deployment of offshore wind energy alter wind climate and reduce future power generation potentials
The large-size of wind farms and their proximity affect not only the performance of its downwind turbines but also that of neighboring downwind farms, reducing the capacity factor by 20% or more, which increases energy production costs and economic losses. ..."
Chinas Atomwaffen: Satellitenbilder deuten auf massive Aufrüstung
China's Xi pledges 'reunification' with Taiwan on communist party's birthday
The Medici: Portraits and Politics, 1512–1570
Thursday, July 01, 2021
Why Tesla's New Cars Come Without Radar Sensors
Trump'd up charges or the double standards Trump vs. Biden with Rob Schmitt
Molecular machines talk to living cells for the first time
‘Ultimately, we want to be able to provide signals to cells and guide their function when they are not able to do that by themselves in disease cases.’ ...
Identifying the Neural Link Between Gut Bacteria and Social Behavior in Mice
It had already been shown that, on a chemical level, germ-free mice have significantly higher levels of the hormone corticosterone (the analog of the so-called stress hormone, cortisol, in humans) than mice with healthy microbiomes. The team of researchers, led by former Mazmanian lab postdoctoral scholar Wei-Li Wu, aimed to identify the neurons that were both affected by corticosterone and played a role in social behaviors. ...
"There are a lot of neurons in the body that respond to corticosterone—called glucocorticoid receptor-positive neurons—and we wanted to know which cell populations and brain regions were then responsible for the altered social behaviors in germ-free mice?" ...
To address this, the team conducted fecal transplants from wild-type mice with normal gut microbiota into germ-free mice. These mice then showed decreased corticosterone levels and more normal social behavior. The team then systematically identified a species of bacteria that mediated this improvement, namely Enterococcus faecalis. Germ-free mice that were colonized with E. faecalis showed improved social behaviors and lowered corticosterone levels. The mechanisms through which E. faecalis is able to mediate this improvement will be the subject of future research. ...
This work strengthens the emerging appreciation of the profound effects of the gut-brain connection ..."
Biden’s White House Payroll Is Most Expensive In American History
-There are 190 more employees on White House staff under Biden than under Trump (377) and 80 more than under Obama (487) at this point in their respective presidencies. ..."
Nature journal: It’s official: China has eliminated malaria
“China’s ability to think outside the box served the country well in its own response to malaria,” Pedro Alonso, director of WHO's Global Malaria Programme, said in a statement."
Who Was the Biggest Mass Murderer in History? The Communist Party of China is celebrating 100 years
Joe Biden’s limited Iraq and Syria strikes won’t stop Iran by Michael Rubin
Biden chose an option that, in his mind, posed the least chance of escalation or Iraqi diplomatic opprobrium. In effect, Biden chose to prioritize symbolism over effectiveness. ...
Quite the contrary; the groups have grown powerful enough that even Prime Minister Mustafa al-Kadhimi not even fears taking substantive action against them, but even attends their parades. ...
Part of the problem for the ineffectiveness of the military option is Biden and Sullivan’s embrace of proportionality. For the Pentagon to calibrate rather than escalate a response leads Iranian strategists to calculate the price of continued drone and rocket strikes is worth it. ...
Zum Ende des Afghanistan-Einsatzes findet niemand aus der Polit-"Elite" Zeit, die Soldaten zu begrüßen
Beyond coronavirus: the virus discoveries transforming biology
There are just 9,110 named species listed by the International Committee on Taxonomy of Viruses (ICTV), but that’s obviously a pitiful fraction of the total. In part, that’s because officially classifying a virus used to require scientists to culture a virus in its host or host cells — a time-consuming if not impossible process. ...
In 2020 alone, the ICTV added 1,044 species to its official list, and thousands more await description and naming. This proliferation of genomes prompted virologists to rethink the way they classify viruses and helped to clarify their evolution. There is strong evidence that viruses emerged multiple times, rather than sprouting from a single origin. ..."
Israel’s High-Powered Laser Weapons System a ‘Breakthrough'
The cost of firing a laser beam for an interception will cost around $2000. Meanwhile, the price of launching an Iron Dome interception missile is between $40,000 and $60,000. ..."





