Good news!
"Key insights in Alzheimer’s research are being fueled by a “massive” new trove of globally shared data—with breakthroughs showing the power and potential of multinational collaboration, per a new series published in Nature.
Background: The Global Neurodegeneration Proteomics Consortium (GNPC), launched in 2023, is now the largest neurodegenerative disease data-sharing effort, including 40,000+ clinical samples and 250 million protein measurements that allow for “unprecedented” research—potentially speeding up the development of diagnostics and therapies by decades.
Discoveries include:
- New insights about APOE4, a gene variant that most strongly increases risk for developing Alzheimer’s, and new proteins associated with the gene.
- New evidence linking different neurodegenerative diseases with aging in other organs, including the liver, intestines, and muscles.
- Identification of protein pathways shared across several neurodegenerative diseases.
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Other breakthroughs: Meanwhile, new research shows that Alzheimer’s-related biomarkers can be detected in the blood of adults as young as 41, per a Finnish study published in The Lancet’s Healthy Longevity—suggesting the disease could be identified decades before symptoms appear ..."
GNPC
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