I bet this is dubious research to elicit alarmism and hysteria! It is a study based on association, prospective and risk analysis.
What about other factors? It seems the study has not made any efforts to rule out other factors.
Plastophobia is a serious disorder. Please see a doctor immediately! Phthalates have been used for several decades! If they were so bad, we probably would know about it for some time.
"... “There is a clear opportunity here to lessen these risks by either using safer plastic materials or by reducing the use of plastic altogether whenever possible,” ..."
"Daily exposure to chemicals used in the manufacture of plastic food containers and many cosmetics may be tied to nearly 56,600 preterm births in the U.S. in 2018, a new study shows. The resulting medical costs, the authors of the report say, were estimated to reach a minimum of $1.6 billion and as much as $8.1 billion over the lifetime of the children.
For decades, the chemicals, called phthalates, have been shown to interfere with the function of certain hormones, or signaling compounds that circulate in the blood and guide much of the body’s processes. ..."
From the abstract:
"Background
Phthalates are synthetic chemicals widely used in consumer products and have been identified to contribute to preterm birth. Existing studies have methodological limitations and potential effects of di-2-ethylhexyl phthalate (DEHP) replacements are poorly characterised. Attributable fractions and costs have not been quantified, limiting the ability to weigh trade-offs involved in ongoing use. We aimed to leverage a large, diverse US cohort to study associations of phthalate metabolites with birthweight and gestational age, and estimate attributable adverse birth outcomes and associated costs.
Methods
In this prospective analysis we used extant data in the US National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program from 1998 to 2022 to study associations of 20 phthalate metabolites with gestational age at birth, birthweight, birth length, and birthweight for gestational age z-scores. We also estimated attributable adverse birth outcomes and associated costs. Mother–child dyads were included in the study if there were one or more urinary phthalate measurements during the index pregnancy; data on child's gestational age and birthweight; and singleton delivery.
Findings
We identified 5006 mother–child dyads from 13 cohorts in the ECHO Program. Phthalic acid, diisodecyl phthalate (DiDP), di-n-octyl phthalate (DnOP), and diisononyl phthalate (DiNP) were most strongly associated with gestational age, birth length, and birthweight, especially compared with DEHP or other metabolite groupings. Although DEHP was associated with preterm birth (odds ratio 1·45 [95% CI 1·05–2·01]), the risks per log10 increase were higher for phthalic acid (2·71 [1·91–3·83]), DiNP (2·25 [1·67–3·00]), DiDP (1·69 [1·25–2·28]), and DnOP (2·90 [1·96–4·23]). We estimated 56 595 (sensitivity analyses 24 003–120 116) phthalate-attributable preterm birth cases in 2018 with associated costs of US$3·84 billion (sensitivity analysis 1·63– 8·14 billion).
Interpretation
In a large, diverse sample of US births, exposure to DEHP, DiDP, DiNP, and DnOP were associated with decreased gestational age and increased risk of preterm birth, suggesting substantial opportunities for prevention. This finding suggests the adverse consequences of substitution of DEHP with chemically similar phthalates and need to regulate chemicals with similar properties as a class. ..."
This is the only figure in this study! Strange! Shoddy?
FigureDistribution of phthalate metabolites in women during pregnancy
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