Alert: Plastophobia is a serious disorder. Please seek immediate medical help! (Caution: satire)
What about all the benefits of plastics in our lives? What are the substitutes?
"... Food packaging is a major source of micro and nanoplastic (MNPLs) contamination and inhalation and ingestion is the main route of human exposure. ..."
From the highlights and abstract:
"Highlights • Nanoplastics were obtained from three teabag brands during a standard preparation. • ATR-FTIR shows nylon, polypropylene, and cellulose as constituents. • MNPLs release was higher for propylene and lower for nylon. • Uptake in Caco-2, HT29, and HT29-MTX human intestinal cells was determined. • Cell uptake depends on both cell type and chemical constitution of released MNPLs. Abstract The potential health implications of environmental micro/nanoplastics (MNPLs) are increasingly concerning. Beyond environmental exposure, other sources such as food packaging, including herbal/teabags, may also be significant. This study investigates the release of MNPLs from three commercially available teabags. By simulating tea preparation, MNPL samples were extracted and characterized using a range of analytical techniques: scanning electron microscopy (SEM), transmission electron microscopy (TEM), attenuated total reflectance/Fourier transform infrared spectroscopy (ATR-FTIR), dynamic light scattering (DLS), laser Doppler velocimetry (LDV), and nanoparticle tracking analysis (NTA). The results confirmed that the teabags were made of nylon-6 (NY6), polypropylene (PP), and cellulose (CL) and that microfibers and nano-range particles (NPLs) were present in the leachates. NTA data revealed that the number of released NPLs was 1.20 × 109/mL (PP; 136.7 nm), 1.35 × 108/mL (CL; 244 nm), and 8.18 × 106/mL (NY6; 138.4). The leachate particles were then stained with iDye Poly-Pink and used to expose three human intestine-derived cell types (Caco-2, HT29, and HT29-MTX) to assess their biointeractions and the role of the mucosubstances in vitro. The results demonstrated that after 24 h of exposure to 100 μg/mL NPLs, there was significant uptake of PP-NPLs in HT29-MTX cells, as a model of cells segregating high amount of mucus. A similar uptake was observed for CL-NPLs in HT29 and HT29-MTX cells, while NY6-NPLs were internalized preferentially in Caco-2 cells. These findings underscore the importance of identifying new environmentally relevant MNPL exposure sources, for developing realistic MNPLs samples, and further investigating their potential human health effects."
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