Modesty and common sense are good for your health!
Unfortunately, besides lung cancer risk (well known) no other health problems are mentioned except substance use disorder.
"... For the study, researchers examined a genome-wide set of genetic variants in individuals from multiple ancestry groups enrolled in the U.S. Department of Veterans Affairs’ Million Veteran Program, one of the world’s largest genetic databases, and incorporated additional information from several other genomic databases. They were able to identify dozens of genetic variants linked to cannabis use disorder and a variety of behavioral and health issues associated with cannabis use disorder. ...
Previous research has shown that roughly one-third of people who use marijuana develop cannabis use disorder, which is defined as a problematic pattern of cannabis use leading to clinically significant impairment or distress. ...
variants of genes that encode for three different types of receptors on neurons were associated with elevated risk for developing cannabis use disorder. ..."
Previous research has shown that roughly one-third of people who use marijuana develop cannabis use disorder, which is defined as a problematic pattern of cannabis use leading to clinically significant impairment or distress. ...
variants of genes that encode for three different types of receptors on neurons were associated with elevated risk for developing cannabis use disorder. ..."
From the abstract:
"As recreational use of cannabis is being decriminalized in many places and medical use widely sanctioned, there are growing concerns about increases in cannabis use disorder (CanUD), which is associated with numerous medical comorbidities. Here we performed a genome-wide association study of CanUD in the Million Veteran Program (MVP), followed by meta-analysis in 1,054,365 individuals (ncases = 64,314) from four broad ancestries designated by the reference panel used for assignment (European n = 886,025, African n = 123,208, admixed American n = 38,289 and East Asian n = 6,843). Population-specific methods were applied to calculate single nucleotide polymorphism-based heritability within each ancestry. Statistically significant single nucleotide polymorphism-based heritability for CanUD was observed in all but the smallest population (East Asian). We discovered genome-wide significant loci unique to each ancestry: 22 in European, 2 each in African and East Asian, and 1 in admixed American ancestries. A genetically informed causal relationship analysis indicated a possible effect of genetic liability for CanUD on lung cancer risk, suggesting potential unanticipated future medical and psychiatric public health consequences that require further study to disentangle from other known risk factors such as cigarette smoking."
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