Good news! It has been said for a very long time that occasional fasting can be very beneficial to your health! Now, we learn if it results in significant sustained weight loss it is perhaps even more beneficial!
Unfortunately, the study appears not to indicate whether any medications were involved and what the effect of the special Chinese diet was.
"It’s estimated that over 400 million people around the world are living with diabetes, though that’s probably an underestimate, as almost half of all cases are undiagnosed. At the very least, 1 in 11 adults suffer from diabetes, and 90% of them have type 2 diabetes. ...
There are few large-scale studies on humans, but a 2019 review found that intermittent fasting may help with problems ranging from obesity and insulin resistance to hypertension and inflammation. ...
The researchers conducted a 3-month study on 36 people with diabetes. They had participants eat only 840 kilocalories for 5 days (the average recommended number is around 2,000 kcal), and then eat normally for 10 days, according to the Chinese dietary guidelines. Over the course of the intervention, more than half (17/36) of those in the intermittent fasting group reversed their diabetes and were still diabetes-free after one year. [incorrect: less than half and 16/36] In another control group, just 1 out of the 36 achieved remission. ...
However, other researchers noted that it’s a small-scale study, and more importantly, the people in the intermittent fasting group lost a lot of weight — something that has been linked to type 2 diabetes improvements. Participants in the intermittent fasting group lost almost 6 kg off weight on average, which makes it nigh impossible to say if it’s the intermittent fasting that’s helping or just the weight loss. ...
“This study reinforces the message that Type 2 diabetes is a reversible condition, and shows that remission is possible in those with diabetes of relatively long duration,” ..."
There are few large-scale studies on humans, but a 2019 review found that intermittent fasting may help with problems ranging from obesity and insulin resistance to hypertension and inflammation. ...
The researchers conducted a 3-month study on 36 people with diabetes. They had participants eat only 840 kilocalories for 5 days (the average recommended number is around 2,000 kcal), and then eat normally for 10 days, according to the Chinese dietary guidelines. Over the course of the intervention, more than half (17/36) of those in the intermittent fasting group reversed their diabetes and were still diabetes-free after one year. [incorrect: less than half and 16/36] In another control group, just 1 out of the 36 achieved remission. ...
However, other researchers noted that it’s a small-scale study, and more importantly, the people in the intermittent fasting group lost a lot of weight — something that has been linked to type 2 diabetes improvements. Participants in the intermittent fasting group lost almost 6 kg off weight on average, which makes it nigh impossible to say if it’s the intermittent fasting that’s helping or just the weight loss. ...
“This study reinforces the message that Type 2 diabetes is a reversible condition, and shows that remission is possible in those with diabetes of relatively long duration,” ..."
From the abstract:
"Context
... Although intermittent fasting diets (IF) are becoming very popular, no studies have investigated their benefit in diabetes remission.
Objective
The present study examined the effectiveness of IF in diabetes remission and potential remission durability.
Methods
Participants between ages 38 and 72 years with a duration of T2D of 1 to 11 years, a body mass index (BMI) of 19.1 to 30.4, 66.7% male, and antidiabetic agent use and/or insulin injection were randomly allocated at a ratio of 1:1 to the Chinese Medical Nutrition Therapy (CMNT) or control group. The primary outcome was diabetes remission, defined as a stable glycated hemoglobin A1c (HbA1c) level of less than 48 mmol/mol (< 6.5%) for at least 3 months after discontinuing all antidiabetic medications. The secondary outcomes included HbA1c level, fasting blood glucose level, blood pressure, weight, quality of life, and medication costs. We conducted a 12-month follow-up to assess the continuation of remission.
Results
On completing the 3-month intervention plus 3-month follow-up, 47.2% (17/36) of participants achieved diabetes remission in the CMNT group, whereas only 2.8% (1/36) of individuals achieved remission in the control group (odds ratio 31.32; 95% CI, 2.39-121.07; P < 0.0001). The mean body weight of participants in the CMNT group was reduced by 5.93 kg (SD 2.47) compared to 0.27 kg (1.43) in the control group. After the 12-month follow-up, 44.4% (16/36) of the participants achieved sustained remission, with an HbA1c level of 6.33% (SD 0.87). The medication costs of the CMNT group were 77.22% lower than those of the control group (60.4/month vs 265.1/month).
Conclusion
This study demonstrated the clinical efficacy of CMNT in achieving diabetes remission for at least 1 year."
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