Tuesday, October 20, 2020

Enzymatic DNA synthesis to store digital data in DNA

Good news! Given the exponential explosion of digital data new storage technologies need to be developed fast.

"... DNA is an ideal storage medium because it is stable over hundreds or thousands of years, has an extraordinary information density, and its information can be efficiently read (decoded) again with advanced sequencing techniques that are continuously getting less expensive. ..."

"... Now, the researchers have applied [maskless] photolithographic techniques from the computer chip industry to enzymatic DNA synthesis, and thus developed a new method to multiplex TdT’s [Terminal deoxynucleotidyl Transferase ] superior DNA writing ability. In their study published in Nature Communications, they demonstrated the parallel synthesis of 12 DNA strands with varying sequences on a 1.2 square millimeter array surface. ..."

Enzymatic DNA synthesis sees the light Controlling a DNA-synthesizing enzyme with photolithographic methods from the computer chip industry facilitates multiplexed writing and storage of digital data in DNA

Here is the link to the underlying research paper:



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