Tuesday, March 08, 2022

Scaremongers: SARS-CoV-2 - The Brain Changer

Although the global Covid-19 pandemic is largely over, the Johns Hopkins Bloomberg School of Public Health will not stop scaremongering the public!
This elite school wants you to live in fear!

Today, their opening article of their daily Global Health NOW newsletter wants us to believe that Covid-19 causes brain damage! No mentioning whether our dynamic and flexible brain can repair any of those reported damages or whether these changes are transient or permanent.

Whether Covid-19 was the cause of these brain changes is also questionable. Two years of isolation due to government mandated lockdowns etc. can also mess up a human brain! It is also unclear from the abstract of the paper whether age differences were properly taken care of.

Further down in the article we read "Older participants had more changes than those who are younger." And indeed Covid-19 has primarily affected only older people (> older than 70).

"SARS-CoV-2 alters the brain’s structure in “significant, deleterious” ways—even in those who experienced mild disease, according to a first-of-its-kind brain imaging study in the UK published in Nature yesterday. 
Oxford researchers and colleagues imaged nearly 800 participants, including 401 people who tested positive for the coronavirus between 2 scans. 
MRI scans revealed specific physical changes to the brains of COVID-19 participants, including a greater reduction in gray matter.
Those who had been infected also had a larger cognitive decline than the uninfected. ..."

From the abstract:
"There is strong evidence for brain-related abnormalities in COVID-19. It remains unknown however whether the impact of SARS-CoV-2 infection can be detected in milder cases, and whether this can reveal possible mechanisms contributing to brain pathology. Here, we investigated brain changes in 785 UK Biobank participants (aged 51–81) imaged twice, including 401 cases who tested positive for infection with SARS-CoV-2 between their two scans, with 141 days on average separating their diagnosis and second scan, and 384 controls. The availability of pre-infection imaging data reduces the likelihood of pre-existing risk factors being misinterpreted as disease effects. We identified significant longitudinal effects when comparing the two groups, including: (i) greater reduction in grey matter thickness and tissue-contrast in the orbitofrontal cortex and parahippocampal gyrus, (ii) greater changes in markers of tissue damage in regions functionally-connected to the primary olfactory cortex, and (iii) greater reduction in global brain size. The infected participants also showed on average larger cognitive decline between the two timepoints. Importantly, these imaging and cognitive longitudinal effects were still seen after excluding the 15 cases who had been hospitalised. These mainly limbic brain imaging results may be the in vivo hallmarks of a degenerative spread of the disease via olfactory pathways, of neuroinflammatory events, or of the loss of sensory input due to anosmia. Whether this deleterious impact can be partially reversed, or whether these effects will persist in the long term, remains to be investigated with additional follow up."

Global Health NOW: SARS-CoV-2—The Brain Changer; Florida Flies in the Face of CDC; and Polio Setbacks in Africa


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