Monday, March 07, 2022

Reprogrammed bacterium turns carbon dioxide into important basic chemicals on industrial scale

Good news! It is long overdue to end all this manufactured paranoia about Global Warming Hoax and Climate Change religion!

It is only a matter of time that human ingenuity comes up with a solution e.g. to convert atmospheric CO2 into something else at any scale!

"Industrial scale carbon-negative production of two commodity chemicals has been achieved for the first time using a genetically modified bacterium that can turn waste carbon dioxide into acetone and isopropanol. ...
To do this, the team mined C. autoethanogenum’s genome for enzymes that enable production of acetone or isopropanol from acetyl-CoA, a common intermediate that’s formed during metabolism. The genes that encode these enzymes were then introduced and tested in different strains of the bacterium to optimise production of acetone and isopropanol. ...
The team eventually created a process that operated at high rates for weeks at a time. This was then piloted at an industrial scale in a 120 litre loop reactor connected to a carbon dioxide waste stream from a steel plant. Analyses revealed that the process locks in 1.79kg and 1.17kg of CO2 into acetone and isopropanol, respectively per kilogram of end product after offsetting carbon emissions during the process."

From the abstract:
"... Here we describe the development of a carbon-negative fermentation route to producing the industrially important chemicals acetone and isopropanol from abundant, low-cost waste gas feedstocks, such as industrial emissions and syngas. Using a combinatorial pathway library approach, we first mined a historical industrial strain collection for superior enzymes that we used to engineer the autotrophic acetogen Clostridium autoethanogenum. Next, we used omics analysis, kinetic modeling and cell-free prototyping to optimize flux. Finally, we scaled-up our optimized strains for continuous production at rates of up to ~3 g/L/h and ~90% selectivity. ... Unlike traditional production processes, which result in release of greenhouse gases, our process fixes carbon. These results show that engineered acetogens enable sustainable, high-efficiency, high-selectivity chemicals production. We expect that our approach can be readily adapted to a wide range of commodity chemicals."

Reprogrammed bacterium turns carbon dioxide into chemicals on industrial scale | Research | Chemistry World





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