Wednesday, March 16, 2022

New Mechanism for Virus-Triggered Autoimmunity Uncovered

Amazing stuff!

"... Now, a study shows that in mice, infection with a roseolovirus leads to the development of autoimmune gastritis later in life, demonstrating a causal link between roseolovirus infection and autoimmunity. ..."

From the abstract:
"Infections with herpesviruses, including human roseoloviruses, have been proposed to cause autoimmune disease ... Herein we show that neonatal MRV [Murine roseolovirus] infection induced autoimmune gastritis (AIG) in adult mice in the absence of ongoing infection. ... These findings strongly suggest that infection with a roseolovirus early in life results in disruption of central tolerance and development of autoimmune disease."

New Mechanism for Virus-Triggered Autoimmunity Uncovered | The Scientist Magazine®




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