Monday, August 17, 2020

Deep learning moves cancer vaccines toward reality

Cancer is history! Machine learning will defeat Cancer soon! This is only the beginning!

It appears that researchers in India are also making progress in this fight against cancer! The more researchers, the better!

"... One of the major steps in the synthesis of personalized cancer vaccines is to computationally predict whether a given peptide will bind with the patient’s Major Histocompatibility Complex (MHC) allele. ... This new deep learning model, which the authors call MHCAttnNet, uses Bi-LSTMs [3] to predict the MHC-peptide binding more accurately than existing methods. “Our model is unique in the way that it not only predicts the binding more accurately, but also highlights the subsequences of amino-acids that are likely to be important in order to make a prediction” ..."

Deep learning moves cancer vaccines toward reality | Technology Org Researchers at the International Institute of Information Technology Bangalore (IIIT Bangalore – https://www.iiitb.ac.in) have designed a method [1] using deep learning that can help researchers in immunology take a big leap toward personalized cancer vaccines by an improved understanding of the underlying biological mechanisms of interaction between cancer cells and the body’s immune system.



Here is the underlying research paper:

MHCAttnNet: predicting MHC-peptide bindings for MHC alleles classes I and II using an attention-based deep neural model

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