Good news! Way to go! The device still seems to be a bit large, but it can probably be more miniaturized.
"A battery-free electronic pill that can help doctors wirelessly analyze molecules generated during vital bodily chemical reactions in the gut has been demonstrated for the first time, say the researchers behind a new study. ...
“If we are doing nutrition monitoring, we can better determine real-time intake of food, real-time uptake of glucose into the body, and so on. If we extend our solution to measure other parameters such as pH, we could do real-time quantified intervention in the form of antacids, for example.” ...
This pill could help analyze the gastrointestinal disorders that affect roughly one in five people at some point in their lives, the scientists note. ...
An outer coating on the new pill helps protect it from stomach acids, which previously were a major barrier to creating an electronic capsule to analyze intestinal metabolites. This coating dissolves in the gut once the pill is out of harm’s way. Once that layer is gone, the pill is free to monitor the intestines. ...
The battery-less design and ultralow-power circuitry used in the capsule helped conserve space and enable significant miniaturization. All in all, the prototype device measures 2.6 centimeters long and 0.9 centimeters in diameter. ..."
“If we are doing nutrition monitoring, we can better determine real-time intake of food, real-time uptake of glucose into the body, and so on. If we extend our solution to measure other parameters such as pH, we could do real-time quantified intervention in the form of antacids, for example.” ...
This pill could help analyze the gastrointestinal disorders that affect roughly one in five people at some point in their lives, the scientists note. ...
An outer coating on the new pill helps protect it from stomach acids, which previously were a major barrier to creating an electronic capsule to analyze intestinal metabolites. This coating dissolves in the gut once the pill is out of harm’s way. Once that layer is gone, the pill is free to monitor the intestines. ...
The battery-less design and ultralow-power circuitry used in the capsule helped conserve space and enable significant miniaturization. All in all, the prototype device measures 2.6 centimeters long and 0.9 centimeters in diameter. ..."
From the abstract:
"Information related to the diverse and dynamic metabolite composition of the small intestine is crucial for the diagnosis and treatment of various diseases. However, our current understanding of the physiochemical dynamics of metabolic processes within the small intestine is limited due to the lack of in situ access to the intestinal environment. Here, we report a demonstration of a battery-free ingestible biosensing system for monitoring metabolites in the small intestine. As a proof of concept, we monitor the intestinal glucose dynamics on a porcine model. Battery-free operation is achieved through a self-powered glucose biofuel cell/biosensor integrated into a circuit that performs energy harvesting, biosensing, and wireless telemetry via a power-to-frequency conversion scheme using magnetic human body communication. Such long-term biochemical analysis could potentially provide critical information regarding the complex and dynamic small intestine metabolic profiles."
A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites (open access)
Fig. 1: Design and sensing mechanism of the ingestible self-powered BFC capsule sensor.
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