Monday, July 25, 2022

Restoring Hearing With Beams of Light

Good news! Amazing stuff! However, this is still in a very early stage of development. 

A new generation of cochlear implants is coming (however not before the next decade)! 

"... Some 466 million people worldwide suffer from disabling hearing loss that requires intervention ...
a new kind of cochlear implant that uses light emitters and genetically altered cells that respond to light. By using precise beams of light instead of electrical current to stimulate the cochlear nerve, we expect our optical cochlear implants to better replicate the full spectral nature of sounds and better mimic natural hearing. We aim to start clinical trials in 2026 and, if all goes well, we could get regulatory approval for our device at the beginning of the next decade. ...
Instead of getting the semiconductor emitter itself into the cochlea, the alternative approach puts the light source, such as a laser diode, farther away in a hermetically sealed titanium housing. Optical fibers then bring the light into the cochlea and to the light-sensitive neurons. ... We’re still thinking about how to get the viral vector to deliver the necessary genes to the correct neurons in the cochlea. The viral vector we’ve used in experiments thus far, an adeno-associated virus, is a harmless virus that has already been approved for use in several gene therapies, and we’re using some genetic tricks and local administration to target cochlear neurons specifically."

The article is actually written by one of the developers of this new device.
Restoring Hearing With Beams of Light - IEEE Spectrum Gene therapy and optoelectronics could radically upgrade hearing for millions of people



No comments: