Thursday, August 30, 2018

The Dawn Of A Brain Cell Revolution

Posted: 8/30/2018

Trigger

Just in the past few weeks two scientific papers were published describing the discovery of two new, different neurons in the human brain:
At least one (dubbed rosehip neurons) of which is unique to human brains but they are not found in mice (rodents).

Expect Much More To Come Fast

After the famous Human Genome Project (completed in 2003), scientists are working on remaining frontiers like the brain (e.g. Human Connectome Project) or the gut (Human Microbiome Project).

Both above papers were published within less than three weeks. You can almost hold your breath as to when the next brain cell discovery will be published (just kidding, don’t try).

In the first paper, we learn that these researchers made use of a new methylation pattern analysis.

Are you ready for the ride of your life! :-)

Tuesday, August 28, 2018

Scientists Are So Blind

Posted: 8/28/2018

Trigger

Just read 3-D Cell Environment Crucial for Divvying Up Chromosomes – Find Could Help Explain Cancer Hallmark. It is very hard to believe that scientists only now realized that cell division (mitosis) does not function well in cells grown in a flat Petri dish as opposed to cells inserted into a living tissue. And this after more than 100 years of intensive research!

Similarities And Synergy

This reminds me that I recently blogged about following, similar discoveries:
  1. Cell organelles have contact sites and tether together (here)
  2. Human fascial system from head to toe (here)

It almost appears that scientists finally discover that the whole is greater than the sum of its parts or that by drilling down into ever more minute details obscures the view of the bigger picture (not seeing the forest for the trees).

Subatomic Particle Physics

Just today (8/28/2018) I read following news from Brookhaven National Laboratory: LHC Scientists Detect Most Favored Higgs Decay Scientists now know the fate of the vast majority of all Higgs bosons produced in the LHC. Quote: “Today at CERN, the Large Hadron Collider collaborations ATLAS and CMS jointly announced the discovery of the Higgs boson transforming into bottom quarks as it decays. This is predicted to be the most common way for Higgs bosons to decay, yet was a difficult signal to isolate because background processes closely mimic the subtle signal.” (emphasis added)

Yes, there was lots of excitement in 2012, when scientists at the  Large Hadron Collider (LHC) of CERN were able to detect the existence of this crucial particle. However, what are we actually dealing with here:
  1. The all so important Higgs boson has a mean lifetime of about 1.6×10−22 s.
  2. “Higgs bosons are only produced in roughly one out of a billion LHC collisions and live only a tiny fraction of a second before their energy is converted into a cascade of other particles.”
  3. “Since its discovery in 2012, scientists have been able to identify only about thirty percent of all the predicted Higgs boson decays.”

To me, it appears that particle physics is going down a dead end. I have previously written some critical comments on particle physics (see e.g. here, here)

Like the once astonishing recognition of the duality of particle and waves, scientists have yet to make sense of the ever growing and more bizarre zoo of subatomic particles. Are they too missing the forest for the trees?

Like Gravity Or Synergy

Something is important is escaping scientists in their quest to further explain the universe we live in and beyond or life therein!

Guess, we have to wait for the next Galileo, Newton, or Einstein!

Sunday, August 26, 2018

Questions & Answers: Natural Language Processing Is Reaching Human Parity

Posted: 8/26/2018

This is the reference standard for measuring questions & answers task in NLP:

As one can see, there are sometimes multiple state of the art submissions per month. With each submission the score is improved by at least 0.1-0.2 percentage points.

The human score is at 86.8%. The best NLP model is currently at 71.7% (as of 8/26/18) or only a 15.1 percentage points gap. A simple extrapolation at an improvement rate of 0.3 percentage points per months, it would take only about 4 years to reach parity on this task. However, progress in AI is made rather by leaps and bounds. Thus, if the average improvement per months is closer to 1 percentage point, it would only take another 15 months to achieve parity.

Given the rapid progress so far and the fierce competition by very capable, competing groups around the world, perhaps less than one year is possible to reach this milestone.

Saturday, August 25, 2018

Nancy Wake - The White Mouse

Posted: 8/25/2018  Update: 8/9/2019

Update Of 8/9/2019

Just watched a short biography documentary about Nancy Wake:
A 20 minutes long Biography video with Simon Whistler. Very recommendable!

Original Post

Just watched this incredible documentary about this very courageous and beautiful woman Nancy Wake: Gestapo's Most Wanted (French Resistance Documentary) | Timeline from near Wellington, New Zealand.

She was a journalist; an ambulance driver; joined British special operations; fought alongside French resistance; she was the most wanted woman by the Nazis with a prize of 5 million francs on her head. James Bond would immediately blush!

She received some of the highest honors of France, the U.S, United Kingdom, Australia, New Zealand.

A breathtaking story. She is my hero! Why the heck is so little known about this absolutely stunning woman!

Saturday, August 18, 2018

Assisted Suicide: A Very Slippery Slope

Posted: 8/17/2018  Update: 9/10/2018

Update Of 9/10/2018

Today, I read this comment (The Ugly Culture Legalizing Physician-Assisted Suicide Would Create), which made a number of excellent points I would like to add here and more.

Some salient quotes from above article (emphasis added):
  1. “... we all play a role in counseling and protecting the sick, the weak, and the elderly, whatever their background or circumstances ...”
  2. “For one, physician-assisted suicide sets up arbitrary guidelines about who receives suicide prevention and who receives suicide assistance.”
  3. “Contrary to the prevalent myth that physician-assisted suicide is mainly an option for those in excruciating pain, studies suggest that the leading cause of physician-assisted suicide is not pain, but existential distress.”
    [Often existential distress is only temporary and can be overcome.]
  4. “When physician-assisted suicide is on the table, so too are less-than-pure motives to choose—or pressure someone to choose—death over life.”
    [What about e.g. those relatives who would like to inherit your estate?]
  5. Family members may be increasingly tempted to think that suicide is what sick or elderly relatives “would have wanted” when facing down the emotional and financial toll of caring for others.”
  6. Patients might think themselves “better off dead” when accounting for the toll that additional medical care might take on their families.”
  7. Patients might withhold information from their doctors for fear they will be counseled to take their own lives.”
  8. “So-called legal “safeguards” are gravely insufficient to protect against these negative social trends. Waiting periods, written requests, sign-offs from physicians—none of these requirements remove the pressure on patients to kill themselves or protect against other forms of abuse.”
  9. Life is treated as disposable, which helps explain why many European countries that have legalized physician-assisted suicide now have expanded into non-voluntary euthanasia.”
  10. “The U.S. is hardly safe from these dangerous trends. Thus far, six states have legalized physician-assisted suicide.”

Physicians are neither angels nor saints. A doctor who feels good about assisted suicide will help anyone asking for it. Some doctor even delight at the opportunity to shorten someone’s life who they think might be a burden to society or if they have homicidal inclinations (not unheard of).


Trigger

Just read this disturbing article: ORGANIZED DEATH IN THE NETHERLANDS When “the time is right” for assisted suicide. This article goes far beyond the Netherlands. Apparently, the number of countries that allow for physician assisted suicide (active or passive) has increased from a few to a dozen or so.

Two Sides Of The Issue

As with most other major societal and civilizational issues, there are at least two issues regarding this topic in conflict with each other:
  1. The individual’s right to end one’s own live if e.g. the individual is terminally ill and greatly suffering with no reasonable hope of improvement
  2. To protect the weak or ill individuals from being eliminated

A Very Slippery Slope

I would argue that assisted suicide is generally a violation of the Hippocratic Oath taken by each doctor. This should never be taken lightly. Whether passive assistance (e.g. providing the pill, but not administering a pill) is sufficient is debatable.

As the article above points out, assisted suicides have quite likely been used to get rid of mentally ill individuals or other individuals, whose life was not appreciated.

More Safeguards Necessary

Clearly more safeguards are urgently necessary to prevent the elimination of unwanted individuals through legal courts or medical regulations etc.

Next Green Revolution Is Imminent

Posted: 8/18/2018


The International Wheat Genome Sequencing Consortium (founded in 2005; a massive collaboration of academic and industry researchers from 20 countries) finally finished sequencing the rather complex wheat genome of 107,000 genes on 21 chromosomes.

One can only imagine what benefits will come next!

Will The FISA Court Finally Stand Up

Posted: 8/18/2018  Updated: 12/18/2019, 9/6/2018

Update Of 12/18/2019


“In a rare public order Tuesday [12/17/2019], the chief judge of the Foreign Intelligence Surveillance Court [FISC] strongly criticized the FBI over its surveillance-application process, giving the bureau until Jan. 10 to come up with solutions, in the wake of findings from Justice Department Inspector General Michael E. Horowitz. The order, from the court's presiding judge Rosemary M. Collyer, came just a week after the release of Horowitz's withering report about the wiretapping of Carter Page, a former campaign adviser to President Trump.”

Here is the link to the public court order: IN RE ACCURACY CONCERNS REGARDING FBI MATTERS SUBMITTED TO THE FISC

Update Of 9/6/2018

Not only does this court not stand up when duped, today I learnt that the FISA court did not hold any  hearings when it approved or extended surveillance warrants (four total warrants) on a campaign advisor (Carter Page) of a presidential election campaign. Can you believe this rubber stamping! This is clearly dereliction of duty if not worse on part of the judges!



Trigger

Another great article by Kimberley A. Strassel in the Wall Street Journal about Watergate II: What Was Bruce Ohr Doing? Justice releases some damning documents, but much of the truth is still classified.

Ms. Strassel is fast becoming the next Bernstein & Woodward (I blogged about this here)

Will The Judges Of The FISA Court Finally Call For An Investigation

From all the information and facts published so far about the abuse of the U.S. Foreign Intelligence Surveillance Court with regards to the Trump campaign by the Obama Administration in collusion with the Clinton Campaign, it is high time that the duped judges on this court do everything in their own power to shed light on this affair!

I am not a law expert, but I am sure the judges of this court could initiate some form of review of the events or have officers of the court disciplined for their malfeasance etc.

Monday, August 06, 2018

U.S. CAFE Standards Are Utterly Unconstitutional

Posted: 8/6/2018

Introduction

I had planned for some time to write a blog post about CAFE (Corporate Average Fuel Economy), but never got around to write it.

It has been absolutely shocking that the elected representatives of the beacon of freedom and individual liberty could have ever passed such an unconstitutional monstrosity of a law in 1975 and never since then bothered to repealed it. According to the Wikipedia article about CAFE (source no. 2), this law was never even seriously challenged in courts. Further, this law set a horrible precedent for the entire world.

Trigger

Just read this Cato Institute article: Trump’s Proposed CAFE Standard. Some salient quotes from this article (emphasis added):
  1. “... when Congress created the CAFE program in 1975, it specially forbade states from adopting their own stronger rules because this would greatly increase the costs of compliance to manufacturers. Despite that, the Obama administration decided to exempt California from the one-national-standard rule. The Trump administration is going back to the actual law.”
    (What a lousy, business adverse president Obama was, this is another example)
  2. “Another important issue is that the CAFE program has suffered mission creep. When Congress created the program in 1975, the nation was suffering from politically induced energy shortages. But the standards weren’t needed to save energy; people responded to higher gas prices by buying more fuel-efficient cars without the government standards.”
    (Mission creep? What a misguided euphemism!)

Brevity Is The Soul Of Wit

CAFE is pure, grandiose socialist central planning; simply and utterly unconstitutional, and should be repealed ASAP!

Sources:

Sunday, August 05, 2018

Cell Organelles Have Contact Sites And Tether Together

Posted: 8/5/2018

Trigger


Science Does Not Know Anything

Or so it seems! Humanity gives way too much credence to science! Socrates forgive me that I have borrowed your famous phrase.

It appears, it was only discovered a few years ago or so that the many and varied organelles (e.g. mitochondria, endoplasmic Reticulum, lysosomes) in our cells have contact sites to contact each other and that they also tether with each other. That is almost incredible after more than 100 years of intense cell research!

““We found that all of the organelles that we tagged are able to physically interact with all of the others,” ... “Tethers organize the cell and assign locations to the organelles. For example, if two organelles must work closely together, they will naturally be tethered together in a certain area of the cell. Tethering also seems to be a way of efficiently transferring, from one organelle to another, certain materials and messages that could do harm in the wrong places …” (emphasis added)

Gracia Mendes Nasi: A Largely Unknown Rich & Successful Business Woman

Posted: 8/5/2018


Trigger


I recently watched this documentary video about Wir Europäer 2 Europa erfindet den Kapitalismus (in German language), where I encountered a mentioning of this lady, i.e. Gracia Mendes Nasi (1510? - 1569), probably for the first time in my life.


Oh girl/[boy], was I stunned for a moment when I learnt of this lady and her almost incredible accomplishments!


Gracia Mendes Nasi


She was also also known by her Christianized name Beatrice de Luna Mendes. Wikipedia describes her as “one of the wealthiest Jewish women of Renaissance Europe”.


Yes, you can argue it was her husband or his family, who created the wealth and she just happened to inherit it. “Francisco [her husband, who died when she was 28 years old] divided his fortune between Beatrice and his brother and business partner, Diogo; this bold decision put Beatrice on the path to becoming the successful and renowned business woman of the sixteenth century ...” Well, was this just an expression of his devotion and love for his wife or was it trust in his wife to take care of business?


According the YouTube audio biography (see source no. 2), this lady was quite a business woman who conducted business all over Europe and even from several different countries. She is apparently also known for her tremendous efforts to help large numbers of European Jews to escape persecution.


For more details about her life, please see sources below.


Conclusion


Feminism is a false ideology and a myth! Women, who dared succeeded!


Sources:

  1. The Life And Death Of Gracia Mendes Nasi (YouTube video; audio biography)
  2. Who Was Dona Gracia Nasi? Jewish Biography as History Dr. Henry Abramson (Had no time yet to watch this YouTube biography of her)