Sunday, April 30, 2023

Since 2010 over 10,000 ancient human genome sequences have been published

Amazing stuff! This is only the beginning! Lot's of potential!

"In 2010, researchers published the first genome sequence from an ancient human, using tufts of hair from a man who lived around 4,000 years ago in Greenland. In the 13 years since, scientists have generated genome data from more than 10,000 ancient people — and there’s no sign of a slowdown. ...
Before 2010, ancient-DNA studies focused on limited stretches of DNA, such as the roughly 16,500-base-pair-long mitochondrial genome or short segments of the nearly 3.1 billion base pairs in the human genome. Since then, advances in DNA sequencing have made it feasible to decode entire ancient genomes. Initially, this process was labour-intensive, and relied on finding rare samples with high levels of genuine ancient DNA. As a result, it took several years to generate genome data from a dozen individuals.
Each year since 2018, researchers have produced genome data from thousands of ancient humans, thanks to technological advances in DNA sequencing and extraction methods. ...
Nearly 80% of ancient-human genome sequences in the database come from just three institutions ... [Harvard Medical School] contributed nearly half of the total (others are based at the University of Copenhagen and two Max Planck Institutes in Germany). ..."

‘Truly gobsmacked’: Ancient-human genome count surpasses 10,000 The majority of sequences come from people who lived in Western Eurasia, but samples from other regions are on the rise.



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