Sunday, April 30, 2023

Expanding our understanding how specific species of bacteria in the gut feelings influence emotional wellbeing

Amazing stuff! Notice, again women are treated in a derogatory way by e.g. using the word "people" despite the fact that this was a study on women only! And the authors of two articles did not fail to mention "mostly white women". Again skin color racism!!!

"Specific species of bacteria were present with higher abundances in women who reported being happier, more hopeful and having better emotion management skills
A new study ... has linked bacteria in our gut to positive emotions like happiness and hopefulness and healthier emotion management skills. ..."

"... The new study included women from a mind-body sub-study of the Nurses’ Health Study II. These middle-aged ... women filled out a survey that asked about their feelings in the last 30 days, asking them to report positive (feeling happy or hopeful about the future) or negative (sad, afraid, worried, restless, hopeless, depressed, or lonely) emotions. The survey also assessed how they handled their emotions. The two options were reframing the situation to see it in a more positive light or suppressing negative emotions.
Three months after answering the survey, the women provided stool samples, which were analyzed using metagenomic sequencing. The team compared the results from the microbial analysis to the survey responses about emotions, looking for connections. ...
The analysis found that [women] who suppressed their emotions had a less diverse gut microbiome. The investigators also found that [women] who reported happier feelings had lower levels of Firmicutes bacterium CAG 94 and Ruminococcaceae bacterium D16. On the other hand, people who had more negative emotions had more of these bacteria. ..."

From the abstract:
"Background
Accumulating evidence suggests that positive and negative emotions, as well as emotion regulation, play key roles in human health and disease. Recent work has shown the gut microbiome is important in modulating mental and physical health through the gut–brain axis. Yet, its association with emotions and emotion regulation are understudied. Here we examined whether positive and negative emotions, as well as two emotion regulation strategies (i.e. cognitive reappraisal and suppression), were associated with the gut microbiome composition and functional pathways in healthy women.
Methods
Participants were from the Mind-Body Study (N = 206, mean age = 61), a sub-study of the Nurses' Health Study II cohort. In 2013, participants completed measures of emotion-related factors. Two pairs of stool samples were collected, 6 months apart, 3 months after emotion-related factors measures were completed. Analyses examined associations of emotion-related factors with gut microbial diversity, overall microbiome structure, and specific species/pathways and adjusted for relevant covariates.
Results
Alpha diversity was negatively associated with suppression. In multivariate analysis, positive emotions were inversely associated with the relative abundance of Firmicutes bacterium CAG 94 and Ruminococcaceae bacterium D16, while negative emotions were directly correlated with the relative abundance of these same species. At the metabolic pathway level, negative emotions were inversely related to the biosynthesis of pantothenate, coenzyme A, and adenosine.
Conclusions
These findings offer human evidence supporting linkages of emotions and related regulatory processes with the gut microbiome and highlight the importance of incorporating the gut microbiome in our understanding of emotion-related factors and their associations with physical health."

Expanding our understanding of gut feelings – Harvard Gazette  Women who suppressed emotions had less diverse microbiomes in study that also found specific bacterial link to happiness

Emotional Wellbeing May be Directly Linked to Women's Gut Health Specific species of bacteria were present with higher abundances in women who reported being happier, more hopeful and having better emotion management skills




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