Good news! Cancer is history!
"... In the years since [2010], five CAR-T cell therapies have been approved by the US Food and Drug Administration, to treat leukaemias, lymphomas and myelomas. June estimates that tens of thousands of people have received CAR-T cell treatment. ...
But the therapy is expensive, risky and technically demanding. It remains a last resort, to be used when all other treatments have failed. Despite the treatment’s success ..., not everyone experiences durable remission of their cancer. In the beginning, only about 25-35% of CAR-T cell recipients with chronic lymphocytic leukaemia experienced a complete remission of their cancer, says Porter. With refinement, that percentage has increased over the years, he says, but some of these initial successes still lead to relapse. Tracking the treatment long-term could reveal clues as to what factors are important for lasting CAR-T cell success. ...
Efforts are underway to use CAR-T cell approaches to treat solid tumours, such as prostate tumours and the devastating brain cancer glioblastoma. In January, researchers reported success in using the cells to destroy scar tissue in the heart — an approach that could one day be used to treat cardiac fibrosis. ..."
But the therapy is expensive, risky and technically demanding. It remains a last resort, to be used when all other treatments have failed. Despite the treatment’s success ..., not everyone experiences durable remission of their cancer. In the beginning, only about 25-35% of CAR-T cell recipients with chronic lymphocytic leukaemia experienced a complete remission of their cancer, says Porter. With refinement, that percentage has increased over the years, he says, but some of these initial successes still lead to relapse. Tracking the treatment long-term could reveal clues as to what factors are important for lasting CAR-T cell success. ...
Efforts are underway to use CAR-T cell approaches to treat solid tumours, such as prostate tumours and the devastating brain cancer glioblastoma. In January, researchers reported success in using the cells to destroy scar tissue in the heart — an approach that could one day be used to treat cardiac fibrosis. ..."
CAR-T cell therapy modifies T-cells
shown here attacking a brain cancer cell — to recognize specific proteins.
shown here attacking a brain cancer cell — to recognize specific proteins.
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