Saturday, March 26, 2016

Hot Recent Science & Technology Articles (25)

Posted: 3/26/2016

Sorry, I did not have the time to annotate as I usually do!

  1. Researchers take small step toward silicon-based life (“Researchers reported … that they have evolved a bacterial enzyme that efficiently incorporates silicon into simple hydrocarbons—a first for life.  … cytochrome c’s silicon-adding ability is so feeble that it’s probably just a byproduct of the enzyme’s function—not even close to its primary role. To try to beef it up, the team incubated the bacteria with silicon and carbon compounds and selected the organisms that produced the most hydrocarbons that incorporated silicon. After only three rounds of this artificial selection, the enzymes had evolved to churn out silicon-containing hydrocarbons 2000 times as readily as natural cytochrome c.”)
  2. Voyage into darkness (“Marine biologists venturing into the polar night—the four winter months of the year when the Arctic sees no sunlight—are finding wondrous discoveries and rewriting the biological textbooks. Arctic dogma has held that the region is mostly dead in the winter, with organisms either dormant or migrated out of the polar region. But in recent journeys scientists have discovered zooplankton in all phases of reproduction, cod actively hunting for zooplankton, and six species of birds actively foraging, ... “)
  3. Hubble unveils monster stars (“The star cluster R136 is already home to the largest known star in the universe, a giant more than 250 times the mass of the sun. Now, astronomers observing the cluster in ultraviolet light using the Hubble Space Telescope have found a total of nine stars with masses of more than 100 suns, the largest collection of very massive stars found to date. This pack of heavyweights … some 170,000 light-years from Earth—burns bright and fast, collectively outshining the sun 30 million times and ejecting every month material equivalent to the mass of Earth. But how they form is a mystery—the current theory of star formation cannot explain how such behemoths could come together from the collapse of a cloud of gas and dust. ”)
  4. Water molecules break bonds through quantum tunneling (Water is a miracle and still unknown to man! " ... And within the smallest possible 3D droplet of water, which consists of just six molecules, those molecules can rearrange themselves not just one at a time, but in sets of two, ... Two molecules can simultaneously break their hydrogen bonds with their neighbors and rotate off one another like gears. The reconfiguration takes place through a subtle effect called quantum tunneling ...")
  5. Lifting molecular brake may have kept primeval cells running (Further progress in the origin of life science! “Szostak’s team therefore enclosed a ribozyme and several other short RNA oligonucleotide strands in fatty acid vesicles. ‘Vesicles containing short RNAs and ribozyme exhibited approximately constant enzyme activity as a function of vesicle volume as the vesicle grew,’ Engelhart says. ‘Without the short RNAs, they exhibited about a 90% drop in specific activity.’”)
  6. Most eccentric planet ever known flashes astronomers with reflected light (Alien contact maybe? (just kidding) “HD 20782 has the most eccentric orbit known, measured at an eccentricity of .96. This means that the planet moves in a nearly flattened ellipse, traveling a long path far from its star and then making a fast and furious slingshot around the star at its closest approach. … to detect a signal of reflected light from the planet known as HD 20782—a "flash" of starlight bouncing off the eccentric planet's atmosphere as it made its closest orbital approach to its star”)
  7. 400,000-year-old fossils from Spain provide earliest genetic evidence of Neandertals (“The nuclear DNA sequences recovered from two specimens secured in this way show that they belong to the Neandertal evolutionary lineage and are more closely related to Neandertals than to Denisovans. This finding indicates that the population divergence between Denisovans and Neandertals had already occurred by 430,000 years ago when the Sima de los Huesos hominins lived. According to Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology "these results provide important anchor points in the timeline of human evolution. They are consistent with a rather early divergence of 550,000 to 750,000 years ago of the modern human lineage from archaic humans".”
  8. Bacterial resistance to copper in the making for thousands of years (“Under the pressure of "copper stress," bacteria have traded DNA that enabled some to outlive the threat, said Slot, who specializes in fungal evolutionary genomics. And over centuries, the genes that lead to copper resistance have bonded, forging an especially tough opponent for the heavy metal, a cluster scientists call the "copper homeostasis and silver resistance island," or CHASRI.”)
  9. Pocket DNA sequencers make real-time diagnostics a reality (“These so-called nanopore sequencers, produced so far by a single company, have suffered from poor accuracy. But this month, researchers reported that the instruments passed an important field test, conducting on-the-spot sequencing of viruses isolated from patients during last year's Ebola epidemic in West Africa. In the lab, meanwhile, other researchers are tweaking sample preparation and data analysis to boost the devices' accuracy and speed. Real-time analyses of pathogens and the rest of life are within reach, ”)
  10. Scientists Identify a Memory Suppressor that May Play a Role in Autism (“Next, Davis and his colleagues tried to uncover which genes miR-980 [microRNA] regulates, identifying 95 specific targets that might fit that bill. Intriguingly, they found that miR-980 targets and inhibits a gene known as A2bp1. This gene previously had been shown to be involved in susceptibility to autism [and epilepsy]. In addition, it works to promote memory.”)
  11. These Glass Discs Can Store Data for Billions of Years  “Five-dimensional” data discs could be the future of information storage (“The idea for this method, known as “five-dimensional storage,” has floated around for a few years since scientists at the United Kingdom’s University of Southampton first demonstrated it in a 2013 paper. Back then, they were only able to code a single 300 kilobyte text file into a glass disc. Three years later, the same scientists say that they believe they have refined the technique to the point where they can code about 360 terabytes of data onto a single disc. … using a femtosecond laser, the scientists engrave the data into the glass disc’s structure. … into a series of miniscule dots. When the disc is read later, a laser interprets the information based off of the three-dimensional position of the dot in the disc, as well as its size and orientation - hence the name five-dimensional storage.”)
  12. Five-dimensional black hole could 'break' general relativity (“The researchers, from the University of Cambridge and Queen Mary University of London, have successfully simulated a black hole shaped like a very thin ring, which gives rise to a series of 'bulges' connected by strings that become thinner over time. These strings eventually become so thin that they pinch off into a series of miniature black holes, similar to how a thin stream of water from a tap breaks up into droplets. Ring-shaped black holes were 'discovered' by theoretical physicists in 2002, but this is the first time that their dynamics have been successfully simulated using supercomputers.”)
  13. Hyperactive magnetic field may have led to one of Earth’s major extinctions (“Rapid reversals of Earth’s magnetic field 550 million years ago destroyed a large part of the ozone layer and let in a flood of ultraviolet radiation, devastating the unusual creatures of the so-called Ediacaran Period and triggering an evolutionary flight from light that led to the Cambrian explosion of animal groups.”)

When Overseas U.S. Journalists Jeopardize The Lives Of U.S. Soldiers

Posted: 3/26/2016

Trigger

As usual I listen to NPR during my morning commute. On Thursday, 3/24/16, I listened to a story by Alice Fordham reporting from the north-east corner of Syria and my jaw dropped. The story is titled “A Remote Syrian Airstrip Hints At A Growing American Military Role”

What Is Wrong Here?

I think this story by NPR is representative of highly irresponsible journalism.

  1. This story gives away way too much valuable information about ongoing U.S. military operations to our enemy (e.g. ISIS)
  2. It is not clear from the story whether NPR or the journalist ran this story by the Pentagon before it was aired and published
  3. Although NPR claims “NPR is not specifying the location out of concern that civilians could be targeted by ISIS.”. It should not be too difficult for our enemies to figure what airstrip it is about given all the hints in the story

Sunday, March 20, 2016

Who Or What Protects Humans From Zealous Animal Rights Activists?

Posted: 3/20/2016


Recent headlines reminded us that the well organized, uncompromising, and singularly  focused animal zealots of the world are getting their way again.


Germany is about to pass a law banning all wild animals from circuses. The heartwarming story of a supposedly mistreated circus bear in Germany that was then taken away from the circus was all over the media. Seaworld just announced it would not breed Orcas anymore and so on.


Here is an article that actually shows that Seaworld actually made contributions to Orca research. See e.g. here.

Zealotry of any kind should be confronted for what it is!

How many of these animal rights activists are misanthropes?

Scientific Reproducibility Or Opinion Polls?

Posted: 3/20/2016

Caveat

As usual, I don’t have the time to more thoroughly investigate this subject. Thus, I am relying here more on hunches and common sense ...

Trigger


Then, we have a recent study to show that a similar result can be obtained from replicating experimental economics studies. See e.g. About 40% of economics experiments fail replication survey. Experimental studies in economics have been suspect for quite some years due to the overuse of young college/university students as subjects.

Scientific Publication Bias

It was argued that reputable scientific journals rather choose sensational studies over less sensational studies. Sure this sells better!

It was reported that scientific journals are already working on improving the selection of articles based on the above studies.

Counter Study


Among other things, the study criticized the sampling used by the above replication study: “... an idiosyncratic, arbitrary list of sampling rules that excluded the majority of psychology’s subfields from the sample, that excluded entire classes of studies whose methods are probably among the best in science from the sample, and so on.” The 98 studies selected were taken from three, probably reputable, psychology journals. Thus, this argument should not matter so much.

They also criticized “the methods introduced statistical error into the data, which led the OSC to significantly underestimate how many of their replications should have failed by chance alone. When this error is taken into account, the number of failures in their data is no greater than one would expect if all 100 of the original findings had been true.” If we apply the “by chance alone” argument, then how many of the 98 studies have achieved their results by chance alone?

I believe, these two Harvard University​ professors got it wrong too. They confused reproduction of scientific results and replication of scientific experiments. Scientific results ought to be kind of robust to some, especially minor, changes (as the Harvard termed it infidelities) in the replication of experiments.

Reproducibility In The Natural Sciences

The above Nature article points out that there are also reproducibility projects under way in e.g. cancer biology. First results seem to indicate that reproducibility is also a challenge. At least in the natural sciences challenges or a refutation lead possible to better studies or approaches.

Quality Of Opinion Polls

I would posit that if the results of scientific studies like the ones above (especially in the social sciences) cannot be reproduced, then they are more like mere opinion polls. The results are very specific to or heavily depend on time, place, and people.

Saturday, March 12, 2016

Pastiche In Classical Music

Posted: 3/12/2016

Introduction

I am by no means an expert on classical music.

I did not grow up with classical music. I only really discovered classical music for myself a few years ago and for several months now I have been listening to all kinds of classical music from all kinds of composers from the past 400 years.

I am truly amazed about the richness and variation of classical music that has developed over the centuries.

About Pastiche

Definition: “an artistic work in a style that imitates that of another work, artist, or period” (Oxford Pocket Dictionary as quoted here, emphasis added)

Description by Encyclopaedia Britannica (EB): “Britannica does not currently have an article on this topic.  … fraudulence in the arts
  • In the composite fraud, or pastiche, the forger combines copies of various parts of another artist’s work to form a new composition and adds a few connecting elements of his own to make it a convincing presentation. This type of forgery is more difficult to detect than the copy. Such a combining of various elements from different pieces can be very deceptive, because a creative artist” (emphasis added)

I disagree with Encyclopedia Britannica that composite fraud should be associated with a pastiche. Actually, what EB is describing is also a process of invention or creativity out of which new things may emerge.

There is little doubt in my mind that classical composers imitated or, to use a modern term, plagiarized music from other composers. Imitation is the sincerest of flattery or acknowledgement! Without pastiche the world would have been a lot poorer!

Intellectual Property Rights - Specifically Copyright

As my blog amply attests, I am not a particular fan of excessive intellectual property rights or intellectual property rights are in the end not property rights at all, because ideas are rarely if ever developed or owned by a single person or company.

I don’t believe that classical music would have been so amazing had similar intellectual property rights existed and were enforced by government before classical music developed.
For the sake of argument, I will assume that copyrights were not really in effect on an international scale before the Berne Convention of 1886. Thus, until about 1886 copyrights were not widely accepted or enforced in Europe or America.

Examples Of Pastiche

This chapter is under construction and definitely not exhaustive as I do not have the time to do more research. Thus, a few stumbled upon examples have to suffice here.

“Mysliveček provided his younger friend Wolfgang Amadeus Mozart with significant compositional models in the genres of symphony, Italian serious opera, and violin concerto; both Wolfgang and his father Leopold Mozart considered him an intimate friend from the time of their first meetings in Bologna in 1770 … He was close to the Mozart family, and there are frequent references to him in the Mozart correspondence.”

“His Violin Concerto No. 1, in G minor, Op. 26 (1866) is one of the most popular Romantic violin concertos. It uses several techniques from Felix Mendelssohn's Violin Concerto in E minor. ”

“"[Joseph] Haydn later remembered Porpora thus: "There was no lack of Asino, Coglione, Birbante [ass, cullion, rascal], and pokes in the ribs, but I put up with it all, for I profited greatly from Porpora in singing, in composition, and in the Italian language."[1] He also said that he had learned from the maestro "the true fundamentals of composition".”

“Nevertheless, his compositions for the instrument mark an epoch in the history of chamber music. His influence was not confined to his own country. Johann Sebastian Bach studied the works of Corelli and based an organ fugue (BWV 579) on Corelli's Opus 3 of 1689. Handel's Opus 6 Concerti Grossi take Corelli's own older Opus 6 Concerti as models, rather than the later three-movement Venetian concerto of Antonio Vivaldi favoured by Bach.”