US imports of Brazilian coffee face 50% tariff

What President Trump forgot to exempt Brazilian coffee from his tariff hikes? What a blunder! This omission can cost him dearly!

Brands Cash in As India's Coffee Market Brews With Excitement with Palki Sharma

No wonder that coffee has become so expensive! Just kidding!

Younger generations of Indians seem to like coffee.
I did not know that India is the sixth largest producer of coffee.

Utah couple finally opens their own Holy Grounds Gourmet Coffee truck

Sunday 3/26/2023: Holy cow! I have a dumm feeling this coffee truck is closed on Sundays! According to the picture below the coffee is served indoors.

Then there is: "Part of the challenge is the perception ... that Utah is a tough market to sell coffee. Some of that is based on the prohibition against coffee for members of The Church of Jesus Christ of Latter-day Saints.

“Hot drinks … are not for the body or belly,” according to The Word of Wisdom, the set of rules set forth in 1833 for what food and drink are forbidden or allowed under doctrines of the Latter-day Saint faith. In recent years, the rules against coffee have been clarified to include drinks with names that include café, caffé, mocha, latte, espresso or anything ending with -ccino."

Searching for great coffee, Utah couple finally opens their own coffee truck

Study probes caffeine’s role in gut health, IBD mentions also chocolate

I have not  yet finished my morning coffee, when I discovered this article in my email! What's in a gut! Caution: This article maybe overpromising!

As a chocolate addict I guess I have to visit Trader Joe's again to get my next half kilogram Belgium chocolate bar for about $6. Pardon my shameless plug, blame my addiction!

"A new study by investigators from Brigham and Women’s Hospital explores exactly what leads to the generation of Th17 cells — an important subtype of cells in the intestine — and uncovers some of the underappreciated molecular players and events that lead to cell differentiation in the gut. One of those players is the purine metabolite xanthine, which is found at high levels in caffeinated foods such as coffee, tea and chocolate. ...
“While illuminating the steps leading to Th17 cell differentiation, the researchers unexpectedly discovered a role for xanthine in the gut.
... “It’s too soon to speculate on whether the amount of xanthine in a cup of coffee leads to helpful or harmful effects in a person’s gut ..."

From the highlights and abstract (I am not exactly sure how coffee relates to xanthine):

"Highlights

• ER stress in intestinal epithelial cells (IEC) drives gut Th17 differentiation

• Th17 cells induced by IEC-ER stress require H2O2 generated by DUOX2/DUOXA2

• IEC-ROS induce Th17 differentiation through purine metabolites, including xanthine

• IEC-ER stress drives microbial Th17 induction even under germ-free conditions

Summary

Intestinal IL-17-producing T helper (Th17) cells are dependent on adherent microbes in the gut for their development. However, how microbial adherence to intestinal epithelial cells (IECs) promotes Th17 cell differentiation remains enigmatic. Here, we found that Th17 cell-inducing gut bacteria generated an unfolded protein response (UPR) in IECs. Furthermore, subtilase cytotoxin expression or genetic removal of X-box binding protein 1 (Xbp1) in IECs caused a UPR and increased Th17 cells, even in antibiotic-treated or germ-free conditions. Mechanistically, UPR activation in IECs enhanced their production of both reactive oxygen species (ROS) and purine metabolites. Treating mice with N-acetyl-cysteine or allopurinol to reduce ROS production and xanthine, respectively, decreased Th17 cells that were associated with an elevated UPR. Th17-related genes also correlated with ER stress and the UPR in humans with inflammatory bowel disease. Overall, we identify a mechanism of intestinal Th17 cell differentiation that emerges from an IEC-associated UPR."

Study probes caffeine’s role in gut health, IBD – Harvard Gazette Researchers find new clues on causes of inflammatory bowel disease

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut (no public access)

Graphical abstract

Vietnam's coffee culture survives 10 years of Starbucks

An south-east Asian country with a coffee culture?

Could it be that the coffee culture in Vietnam is influenced by the former colonizer France?

Disclaimer: I am not an expert on the coffee culture in Vietnam.

The French like e.g. café au lait something Starbucks does not offer at least not in the U.S..

"Coffee is steeped in the local identity in Vietnam, which boasts more cafes than almost any place on earth. So when Starbucks entered the market in 2013, it faced a different set of expectations than other U.S. brands like McDonald's and Subway, which also debuted in the 2010s.

People wondered how the world's biggest coffee chain would fare in a country that is the world's largest exporter of robusta beans.

The Seattle-based chain itself has been quiet about its progress. The company told Nikkei Asia it will mark 10 years in Vietnam by opening its 100th location but declined to answer a question about whether it is profitable in the country. ..."

Vietnam's coffee culture survives 10 years of Starbucks - Nikkei Asia Deep history, popularity of local brews make country hard for global brands to crack

Brew: A Brief History of Coffee

Very recommendable! London coffee houses became known as penny universities! The French and the American Revolution were planned in coffee houses! Where did the expression a cup of Joe come from? Drip coffee with a paper filter was invented in about 1908 by a Woman by the name of Amalie Auguste Melitta Bentz!

Coffee and the Maya in Guatemala

Recommendable! Perhaps after watching this documentary your coffee will taste even better! Germans were apparently running coffee growing in Guatemala before World War II. A Swiss man has spent 30 years of his life to help to establish viable coffee cooperatives.

Coffee linked to improved survival in metastatic colorectal cancer

I second to that and drink some more coffee!

"In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Harvard-affiliated  Dana-Farber Cancer Institute and other organizations report in a new study. ..."

Coffee linked to improved survival in metastatic colorectal cancer – Harvard Gazette Daily consumption associated with improved survival in patients with metastatic colorectal cancer