Friday, October 03, 2025

Diabetes drug and antihistamine could together repair multiple sclerosis damage, trial finds

Good news! It appears, the results of this study are not yet published in a journal.

"A combination of metformin, a common diabetes drug, and clemastine, an antihistamine, can help repair myelin – the protective coating around nerves, which gets damaged in multiple sclerosis (MS) causing symptoms like fatigue, pain, spasms and problems with walking. ...

Some 70 people with relapsing MS took part in the trials for six months, half of whom took the drug combination and half took a placebo. The primary outcome used to gauge the effectiveness of the drug was a ‘visual evoked potential’ test, which measures how quickly signals travel between the eyes and the brain. The speed of signals slowed down in the placebo group over the course of six months, but remained constant in the drug group. ..."

Diabetes drug and antihistamine could together repair multiple sclerosis damage, trial finds | University of Cambridge "Scientists behind the trial say they are “on the brink of a new class of treatments” and that the findings take us another step closer to stopping disease progression in MS."

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