Thursday, November 07, 2024

The Coming global Cancer Wave. Really!

What a hogwash! When ideology/ulterior motives trump facts and science! 

I bet cancer is history in about 10-20 years!

I also bet this study was driven by pecuniary motives, i.e. to gain more research etc. funding!

To keep things in perspective: Only 35 million cancer cases by 2050. Currently, the world population stands at 8.2 billion. This is equivalent to 0.00004375. This is far, far less than 1% of global population!

"The Coming Cancer Wave

Cancer deaths worldwide will nearly double by 2050, driven mostly by large increases in LMICs, according to a new JAMA Network Open article.
Annual cancer deaths are expected to increase by 90% to 18.5 million cancer deaths by 2050 from 9.7 million in 2022.

Cancer deaths in LMICs by 2050 will increase by 146%, while the increase in high-income countries will be 57%, according to the estimates.

Cancer cases and deaths in Africa are projected to increase at a rate 5X that of Europe.
What’s behind the global increase? Among the multiple factors is the fact that people are living longer (which raises cancer risk) ...
 
And the much greater surge in LMICs? Chan blames the “Westernisation [???] of populations,” including rising obesity rates and poor diets.
 
What’s needed? “Higher-quality health care and universal health insurance [???] coverage would help prevent, diagnose and treat cancer around the world,” ...

From the key points and abstract:
"Key Points
Question  What were the global disparities in cancer burden by cancer type, sex, age, Human Development Index (HDI), regions, and countries and territories in 2022, and how are these epidemiological patterns projected to change by 2050?

Findings  In this cross-sectional study of data for 36 cancer types from 185 countries and territories, cancer disparities were evident across HDI, region, age, and sex in 2022 and are projected to widen by 2050. Cancer cases and deaths are expected to rise by 77% and 90% in 2050, respectively, with a 3-fold increase in low-HDI countries compared with a modest increase in very high–HDI countries (142% vs 42% for cancer cases and 146% vs 57% for cancer deaths).

Meaning  These findings suggest that enhancing health care systems for cancer prevention, early diagnosis, management, and treatment is vital to better address existing disparities in cancer outcomes and slow projected trends.

Abstract
Importance  Cancer prevention and care efforts have been challenged by the COVID-19 pandemic and armed conflicts, resulting in a decline in the global Human Development Index (HDI), particularly in low- and middle-income countries. These challenges and subsequent shifts in health care priorities underscore the need to continuously monitor cancer outcome disparities and statistics globally to ensure delivery of equitable and optimal cancer prevention and care in uncertain times.

Objective  To measure the global burden of 36 cancers in 2022 by sex, age, and geographic location and to project future trends by 2050.

Design, Setting, and Participants  This cross-sectional study used population-based data from 2022 in 185 countries and territories were obtained from the Global Cancer Observatory database. Data extraction and analysis were carried out in April 2024.

Main Outcomes and Measures  Counts, rates, prevalence, mortality to incidence ratios (MIRs), and demography-based projections were used to characterize current and future cancer burden.

Results  This population-based study included 36 cancer types from 185 countries and territories. By 2050, 35.3 million cancer cases worldwide are expected, a 76.6% increase from the 2022 estimate of 20 million. Similarly, 18.5 million cancer deaths are projected by 2050, an 89.7% increase from the 2022 estimate of 9.7 million. Cancer cases and deaths are projected to nearly triple in low-HDI countries by 2050, compared to a moderate increase in very high–HDI countries (142.1% vs 41.7% for cancer cases and 146.1% vs 56.8% for cancer deaths). Males had a higher incidence and greater number of deaths in 2022 than females, with this disparity projected to widen by up to 16.0% in 2050. In 2022, the MIR for all cancers was 46.6%, with higher MIRs observed for pancreatic cancer (89.4%), among males (51.7%), among those aged 75 years or older (64.3%), in low-HDI countries (69.9%), and in the African region (67.2%).

Conclusions and Relevance  In this cross-sectional study based on data from 2022, cancer disparities were evident across HDI, geographic regions, age, and sex, with further widening projected by 2050. These findings suggest that strengthening access to and quality of health care, including universal health insurance coverage, is key to providing evidence-based cancer prevention, diagnostics, and care."

Global Health NOW: The Coming Cancer Wave; Ketamine’s Surge Among Gen Z; and A Moment That Calls for Cuteness



Figure 1.  Worldwide Projected Number of Cancer Cases and Deaths by Sex, 2022-2050


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